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Parkinson's disease: The non-motor issues

Chaudhuri, K. Ray; Odin, Per LU ; Antonini, Angelo and Martinez-Martin, Pablo (2011) In Parkinsonism & Related Disorders 17(10). p.717-723
Abstract
Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and under-researched when taken as a whole. Data is emerging that it is the "totaL" burden of NMS that is the major determinant of quality of life not a single NMS such as depression for instance. Only recently validated tools such as the NMSQuest which empowers patients to declare NMS and the NMS scale, the SCOPA scales, and the modified version of the MDS-UPDRS have become available and validated for bedside clinical assessment of NMS. For the first time clinical trials have been incorporating non-motor measures as outcome measures and clinical recommendations for treatment of non-motor symptoms of PD are being published. This review aims to address some of... (More)
Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and under-researched when taken as a whole. Data is emerging that it is the "totaL" burden of NMS that is the major determinant of quality of life not a single NMS such as depression for instance. Only recently validated tools such as the NMSQuest which empowers patients to declare NMS and the NMS scale, the SCOPA scales, and the modified version of the MDS-UPDRS have become available and validated for bedside clinical assessment of NMS. For the first time clinical trials have been incorporating non-motor measures as outcome measures and clinical recommendations for treatment of non-motor symptoms of PD are being published. This review aims to address some of these topical and "real life" aspects of modern day management of Parkinson's. (C) 2011 Published by Elsevier Ltd. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Non-motor symptoms, Parkinson's disease, Non-motor off period, NMSQuest
in
Parkinsonism & Related Disorders
volume
17
issue
10
pages
717 - 723
publisher
Elsevier
external identifiers
  • wos:000298201600001
  • scopus:80455176827
ISSN
1873-5126
DOI
10.1016/j.parkreldis.2011.02.018
language
English
LU publication?
yes
id
b45178fb-9be6-41ba-bf72-2c1f3f426cd4 (old id 2333324)
date added to LUP
2012-02-01 07:38:29
date last changed
2017-11-12 03:09:37
@article{b45178fb-9be6-41ba-bf72-2c1f3f426cd4,
  abstract     = {Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and under-researched when taken as a whole. Data is emerging that it is the "totaL" burden of NMS that is the major determinant of quality of life not a single NMS such as depression for instance. Only recently validated tools such as the NMSQuest which empowers patients to declare NMS and the NMS scale, the SCOPA scales, and the modified version of the MDS-UPDRS have become available and validated for bedside clinical assessment of NMS. For the first time clinical trials have been incorporating non-motor measures as outcome measures and clinical recommendations for treatment of non-motor symptoms of PD are being published. This review aims to address some of these topical and "real life" aspects of modern day management of Parkinson's. (C) 2011 Published by Elsevier Ltd.},
  author       = {Chaudhuri, K. Ray and Odin, Per and Antonini, Angelo and Martinez-Martin, Pablo},
  issn         = {1873-5126},
  keyword      = {Non-motor symptoms,Parkinson's disease,Non-motor off period,NMSQuest},
  language     = {eng},
  number       = {10},
  pages        = {717--723},
  publisher    = {Elsevier},
  series       = {Parkinsonism & Related Disorders},
  title        = {Parkinson's disease: The non-motor issues},
  url          = {http://dx.doi.org/10.1016/j.parkreldis.2011.02.018},
  volume       = {17},
  year         = {2011},
}