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The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK

Ageberg, Malin LU ; Gullberg, Urban LU and Lindmark, Anders LU (2006) In Haematologica 91(2). p.268-269
Abstract
The role of the DEK protein, involved in the leukemia-associated fusion protein DEK-CAN, is not yet known. In this study, we show a higher expression of DEK mRNA in immature cells than in mature cells. Furthermore, a correlation between DEK expression and cell proliferation was demonstrated, suggesting that DEK plays a role in the proliferation of hematopoietic cells and raising the question of whether the DEK-CAN fusion protein might perturb regulation of proliferation in leukemic cells.
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
leukemia, DEK, proliferation
in
Haematologica
volume
91
issue
2
pages
268 - 269
publisher
Ferrata Storti Foundation
external identifiers
  • pmid:16461319
  • wos:000235481300031
  • scopus:33644525948
ISSN
1592-8721
language
English
LU publication?
yes
id
23d1cfe4-0177-4202-bb01-f468ecc3102f (old id 417502)
alternative location
http://www.haematologica.org/journal/2006/910268.pdf
date added to LUP
2016-04-01 16:51:13
date last changed
2025-10-14 08:57:43
@article{23d1cfe4-0177-4202-bb01-f468ecc3102f,
  abstract     = {{The role of the DEK protein, involved in the leukemia-associated fusion protein DEK-CAN, is not yet known. In this study, we show a higher expression of DEK mRNA in immature cells than in mature cells. Furthermore, a correlation between DEK expression and cell proliferation was demonstrated, suggesting that DEK plays a role in the proliferation of hematopoietic cells and raising the question of whether the DEK-CAN fusion protein might perturb regulation of proliferation in leukemic cells.}},
  author       = {{Ageberg, Malin and Gullberg, Urban and Lindmark, Anders}},
  issn         = {{1592-8721}},
  keywords     = {{leukemia; DEK; proliferation}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{268--269}},
  publisher    = {{Ferrata Storti Foundation}},
  series       = {{Haematologica}},
  title        = {{The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK}},
  url          = {{http://www.haematologica.org/journal/2006/910268.pdf}},
  volume       = {{91}},
  year         = {{2006}},
}