The value of Stanford integrated psychosocial assessment for transplantation (SIPAT) in prediction of clinical outcomes following left ventricular assist device (LVAD) implantation
(2019) In Heart and Lung 48(2). p.85-89- Abstract
Background: The Stanford integrated psychosocial assessment for transplantation (SIPAT) is a validated psychosocial evaluation tool in the transplant population. Objective: We evaluated SIPAT in predicting post-left ventricular assist device (LVAD) outcomes, including cumulative re-admissions, driveline infections, pump malfunction, pump thrombosis, gastrointestinal bleeding, major bleeding, stroke and right ventricular failure. Methods: This retrospective study included 50 LVAD patients at an academic institution in the United States who had a pre-implant SIPAT score during the years 2015-2017. Patients were split into two groups based on SIPAT score, separating a “excellent”/“good” from a “minimally acceptable”/“poor” candidate.... (More)
Background: The Stanford integrated psychosocial assessment for transplantation (SIPAT) is a validated psychosocial evaluation tool in the transplant population. Objective: We evaluated SIPAT in predicting post-left ventricular assist device (LVAD) outcomes, including cumulative re-admissions, driveline infections, pump malfunction, pump thrombosis, gastrointestinal bleeding, major bleeding, stroke and right ventricular failure. Methods: This retrospective study included 50 LVAD patients at an academic institution in the United States who had a pre-implant SIPAT score during the years 2015-2017. Patients were split into two groups based on SIPAT score, separating a “excellent”/“good” from a “minimally acceptable”/“poor” candidate. Poisson regression, using SIPAT as both a categorical and continuous variable, was used to compare the incidence rates of the primary outcome of cumulative re-admissions and secondary outcomes of LVAD complications. Results: The patient cohort was predominantly male 93.5% vs 89.4% (p = 0.629) with a median age of 67.0 vs 58.0 years (p = 0.037), planned destination therapy 48.4% vs 68.4% (p = 0.242) and median LVAD follow-up time of 241 vs 379 days (p = 0.10) in the low- and high- SIPAT groups, respectively. SIPAT was not a significant predictor for cumulative re-admissions, but there was an association between higher SIPAT scores and major bleeding. Conclusion: In this single-center retrospective study, SIPAT did not predict cumulative re-admissions. Further study is required to validate SIPAT before clinical implementation.
(Less)
- author
- Bui, Quan M. ; Braun, Oscar O. LU ; Brambatti, Michela ; Gernhofer, Yan K. ; Hernandez, Holly ; Pretorius, Victor and Adler, Eric
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Complications, LVAD, Psychosocial, Readmission, Transplant
- in
- Heart and Lung
- volume
- 48
- issue
- 2
- pages
- 85 - 89
- publisher
- Elsevier
- external identifiers
-
- scopus:85053350406
- pmid:30227993
- ISSN
- 0147-9563
- DOI
- 10.1016/j.hrtlng.2018.08.011
- language
- English
- LU publication?
- yes
- id
- 23dc3eff-03db-4b07-9911-78232ead203c
- date added to LUP
- 2018-10-26 08:03:40
- date last changed
- 2024-04-01 13:06:57
@article{23dc3eff-03db-4b07-9911-78232ead203c,
abstract = {{<p>Background: The Stanford integrated psychosocial assessment for transplantation (SIPAT) is a validated psychosocial evaluation tool in the transplant population. Objective: We evaluated SIPAT in predicting post-left ventricular assist device (LVAD) outcomes, including cumulative re-admissions, driveline infections, pump malfunction, pump thrombosis, gastrointestinal bleeding, major bleeding, stroke and right ventricular failure. Methods: This retrospective study included 50 LVAD patients at an academic institution in the United States who had a pre-implant SIPAT score during the years 2015-2017. Patients were split into two groups based on SIPAT score, separating a “excellent”/“good” from a “minimally acceptable”/“poor” candidate. Poisson regression, using SIPAT as both a categorical and continuous variable, was used to compare the incidence rates of the primary outcome of cumulative re-admissions and secondary outcomes of LVAD complications. Results: The patient cohort was predominantly male 93.5% vs 89.4% (p = 0.629) with a median age of 67.0 vs 58.0 years (p = 0.037), planned destination therapy 48.4% vs 68.4% (p = 0.242) and median LVAD follow-up time of 241 vs 379 days (p = 0.10) in the low- and high- SIPAT groups, respectively. SIPAT was not a significant predictor for cumulative re-admissions, but there was an association between higher SIPAT scores and major bleeding. Conclusion: In this single-center retrospective study, SIPAT did not predict cumulative re-admissions. Further study is required to validate SIPAT before clinical implementation.</p>}},
author = {{Bui, Quan M. and Braun, Oscar O. and Brambatti, Michela and Gernhofer, Yan K. and Hernandez, Holly and Pretorius, Victor and Adler, Eric}},
issn = {{0147-9563}},
keywords = {{Complications; LVAD; Psychosocial; Readmission; Transplant}},
language = {{eng}},
number = {{2}},
pages = {{85--89}},
publisher = {{Elsevier}},
series = {{Heart and Lung}},
title = {{The value of Stanford integrated psychosocial assessment for transplantation (SIPAT) in prediction of clinical outcomes following left ventricular assist device (LVAD) implantation}},
url = {{http://dx.doi.org/10.1016/j.hrtlng.2018.08.011}},
doi = {{10.1016/j.hrtlng.2018.08.011}},
volume = {{48}},
year = {{2019}},
}