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Airways symptoms, immunological response and exposure in powder painting

Blomqvist, A; Düzakin, Meltem LU ; Ohlson, C G; Andersson, L; Jönsson, Bo A LU ; Nielsen, Jörn LU and Welinder, Hans LU (2005) In International Archives of Occupational and Environmental Health 78(2). p.123-131
Abstract
Objectives: Powder painting is an alternative to solvent-based spray painting. Powder paints may contain organic acid anhydrides (OAAs), which are irritants to the airways and may cause sensitisation. The aim of this study was to determine the prevalence of respiratory symptoms and immunological response among powder painters and to describe the exposure to OAAs. Methods: In all, 205 subjects in 32 enterprises participated: 93 exposed and 26 formerly exposed workers in 25 powder paint shops and 86 unexposed workers. They completed a questionnaire about working conditions and symptoms and took part in a medical examination, which included a lung function test. Urine samples, for determination of two OAAs, and blood samples, for analysis of... (More)
Objectives: Powder painting is an alternative to solvent-based spray painting. Powder paints may contain organic acid anhydrides (OAAs), which are irritants to the airways and may cause sensitisation. The aim of this study was to determine the prevalence of respiratory symptoms and immunological response among powder painters and to describe the exposure to OAAs. Methods: In all, 205 subjects in 32 enterprises participated: 93 exposed and 26 formerly exposed workers in 25 powder paint shops and 86 unexposed workers. They completed a questionnaire about working conditions and symptoms and took part in a medical examination, which included a lung function test. Urine samples, for determination of two OAAs, and blood samples, for analysis of specific antibodies against the OAAs, were taken. In addition, 33 paint samples were analysed for nine OAAs. Results: The powder painters reported more work-related respiratory symptoms than unexposed subjects did. The prevalence of three or more symptoms was 24% in subjects with low exposure, 44% in highly exposed individuals, 46% in formerly exposed subjects and 19% in unexposed workers. Asthma symptoms were frequent, 7%, 40%, 15% and 2%, respectively. Regression analyses of the lung volumes did not show any influence of exposure. IgG, but not IgE, against the OAAs and metabolites of OAAs was found in some subjects, but no associations with the exposure could be observed. OAAs were found in only small amounts in the paint samples. Conclusions: The exposure to organic acid anhydrides was estimated to be low, and yet, IgG antibodies to OAA were observed in some subjects. The prevalence of work-related symptoms from the eyes and the airways was relatively high among the powder painters, and these symptoms, but not the lung volumes, were clearly related to exposure. The symptoms were probably caused by irritative properties of the powder paint dust. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
symptoms, respiratory, asthma symptoms, powder painting, organic acid anhydrides
in
International Archives of Occupational and Environmental Health
volume
78
issue
2
pages
123 - 131
publisher
Springer
external identifiers
  • pmid:15726393
  • wos:000228971800005
  • scopus:17544377782
ISSN
1432-1246
DOI
10.1007/s00420-004-0573-7
language
English
LU publication?
yes
id
1118531f-761d-40ba-b7b5-1a36fcb09915 (old id 240530)
date added to LUP
2007-08-02 12:20:56
date last changed
2017-01-01 06:47:56
@article{1118531f-761d-40ba-b7b5-1a36fcb09915,
  abstract     = {Objectives: Powder painting is an alternative to solvent-based spray painting. Powder paints may contain organic acid anhydrides (OAAs), which are irritants to the airways and may cause sensitisation. The aim of this study was to determine the prevalence of respiratory symptoms and immunological response among powder painters and to describe the exposure to OAAs. Methods: In all, 205 subjects in 32 enterprises participated: 93 exposed and 26 formerly exposed workers in 25 powder paint shops and 86 unexposed workers. They completed a questionnaire about working conditions and symptoms and took part in a medical examination, which included a lung function test. Urine samples, for determination of two OAAs, and blood samples, for analysis of specific antibodies against the OAAs, were taken. In addition, 33 paint samples were analysed for nine OAAs. Results: The powder painters reported more work-related respiratory symptoms than unexposed subjects did. The prevalence of three or more symptoms was 24% in subjects with low exposure, 44% in highly exposed individuals, 46% in formerly exposed subjects and 19% in unexposed workers. Asthma symptoms were frequent, 7%, 40%, 15% and 2%, respectively. Regression analyses of the lung volumes did not show any influence of exposure. IgG, but not IgE, against the OAAs and metabolites of OAAs was found in some subjects, but no associations with the exposure could be observed. OAAs were found in only small amounts in the paint samples. Conclusions: The exposure to organic acid anhydrides was estimated to be low, and yet, IgG antibodies to OAA were observed in some subjects. The prevalence of work-related symptoms from the eyes and the airways was relatively high among the powder painters, and these symptoms, but not the lung volumes, were clearly related to exposure. The symptoms were probably caused by irritative properties of the powder paint dust.},
  author       = {Blomqvist, A and Düzakin, Meltem and Ohlson, C G and Andersson, L and Jönsson, Bo A and Nielsen, Jörn and Welinder, Hans},
  issn         = {1432-1246},
  keyword      = {symptoms,respiratory,asthma symptoms,powder painting,organic acid anhydrides},
  language     = {eng},
  number       = {2},
  pages        = {123--131},
  publisher    = {Springer},
  series       = {International Archives of Occupational and Environmental Health},
  title        = {Airways symptoms, immunological response and exposure in powder painting},
  url          = {http://dx.doi.org/10.1007/s00420-004-0573-7},
  volume       = {78},
  year         = {2005},
}