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Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

Sacks, David B.; Arnold, Mark; Bakris, George L.; Bruns, David E.; Horvath, Andrea Rita; Kirkman, M. Sue; Lernmark, Ake LU ; Metzger, Boyd E. and Nathan, David M. (2011) In Diabetes Care 34(6). p.61-99
Abstract

BACKGROUND - Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH - An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A newsystemwas developed to grade the overall quality of the evidence and the strength of the recommendations. Draft guidelines were posted on the Internet and presented at the 2007 Arnold O. Beckman Conference. The document was modified in response to oral andwritten comments, and a revised draftwas posted in 2010 and againmodified in response to written comments. The National Academy of Clinical Biochemistry... (More)

BACKGROUND - Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH - An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A newsystemwas developed to grade the overall quality of the evidence and the strength of the recommendations. Draft guidelines were posted on the Internet and presented at the 2007 Arnold O. Beckman Conference. The document was modified in response to oral andwritten comments, and a revised draftwas posted in 2010 and againmodified in response to written comments. The National Academy of Clinical Biochemistry and the Evidence-Based Laboratory Medicine Committee of the American Association for Clinical Chemistry jointly reviewed the guidelines, which were accepted after revisions by the Professional Practice Committee and subsequently approved by the Executive Committee of the American Diabetes Association. CONTENT - In addition to long-standing criteria based on measurement of plasma glucose, diabetes can be diagnosed by demonstrating increased blood hemoglobin A 1c (HbA1c) concentrations. Monitoring of glycemic control is performed by self-monitoring of plasma or blood glucose with meters and by laboratory analysis of HbA1c. The potential roles of noninvasive glucosemonitoring, genetic testing, andmeasurement of autoantibodies, urine albumin, insulin, proinsulin, C-peptide, and other analytes are addressed. SUMMARY - The guidelines provide specific recommendations that are based on published data or derived from expert consensus. Several analytes have minimal clinical value at present, and their measurement is not recommended.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetes Care
volume
34
issue
6
pages
61 - 99
publisher
American Diabetes Association
external identifiers
  • scopus:80051981694
ISSN
0149-5992
DOI
10.2337/dc11-9998
language
English
LU publication?
yes
id
241fc583-71a2-4d82-b842-11b9e602c43d
date added to LUP
2017-09-07 12:44:35
date last changed
2017-11-19 04:43:01
@article{241fc583-71a2-4d82-b842-11b9e602c43d,
  abstract     = {<p>BACKGROUND - Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH - An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A newsystemwas developed to grade the overall quality of the evidence and the strength of the recommendations. Draft guidelines were posted on the Internet and presented at the 2007 Arnold O. Beckman Conference. The document was modified in response to oral andwritten comments, and a revised draftwas posted in 2010 and againmodified in response to written comments. The National Academy of Clinical Biochemistry and the Evidence-Based Laboratory Medicine Committee of the American Association for Clinical Chemistry jointly reviewed the guidelines, which were accepted after revisions by the Professional Practice Committee and subsequently approved by the Executive Committee of the American Diabetes Association. CONTENT - In addition to long-standing criteria based on measurement of plasma glucose, diabetes can be diagnosed by demonstrating increased blood hemoglobin A <sub>1c</sub> (HbA<sub>1c</sub>) concentrations. Monitoring of glycemic control is performed by self-monitoring of plasma or blood glucose with meters and by laboratory analysis of HbA<sub>1c</sub>. The potential roles of noninvasive glucosemonitoring, genetic testing, andmeasurement of autoantibodies, urine albumin, insulin, proinsulin, C-peptide, and other analytes are addressed. SUMMARY - The guidelines provide specific recommendations that are based on published data or derived from expert consensus. Several analytes have minimal clinical value at present, and their measurement is not recommended.</p>},
  author       = {Sacks, David B. and Arnold, Mark and Bakris, George L. and Bruns, David E. and Horvath, Andrea Rita and Kirkman, M. Sue and Lernmark, Ake and Metzger, Boyd E. and Nathan, David M.},
  issn         = {0149-5992},
  language     = {eng},
  number       = {6},
  pages        = {61--99},
  publisher    = {American Diabetes Association},
  series       = {Diabetes Care},
  title        = {Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus},
  url          = {http://dx.doi.org/10.2337/dc11-9998},
  volume       = {34},
  year         = {2011},
}