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Motor, mental and behavioral developments in infancy are associated with fatty acid pattern in breast milk and plasma of premature infants.

Sabel, K-G; Strandvik, B; Petzold, M and Lundqvist, Cristina LU (2012) In Prostaglandins, Leukotrienes and Essential Fatty Acids 86(4-5). p.183-188
Abstract
The objective of this study was to investigate any association between infants' early development and PUFA concentrations in early breast milk and infants' plasma phospholipids at 44 weeks gestational age. Fifty-one premature infants were included. The quality of general movement was assessed at 3 months, and motor, mental and behavioral development at 3, 6, 10 and 18 months corrected age using Bayley's Scales of Infant Development (BSID-II). Linoleic acid, the major n-6/n-3 FA ratios, Mead acid and the EFA deficiency index in early breast milk were negatively associated with development up to 18 months of age. DHA and AA, respectively, in infants' plasma phospholipids was positively, but the AA/DHA ratio negatively, associated with... (More)
The objective of this study was to investigate any association between infants' early development and PUFA concentrations in early breast milk and infants' plasma phospholipids at 44 weeks gestational age. Fifty-one premature infants were included. The quality of general movement was assessed at 3 months, and motor, mental and behavioral development at 3, 6, 10 and 18 months corrected age using Bayley's Scales of Infant Development (BSID-II). Linoleic acid, the major n-6/n-3 FA ratios, Mead acid and the EFA deficiency index in early breast milk were negatively associated with development up to 18 months of age. DHA and AA, respectively, in infants' plasma phospholipids was positively, but the AA/DHA ratio negatively, associated with development from 6 to 18 months of age. Our data suggest that the commonly found high n-6 concentration in breast milk is associated with less favorable motor, mental and behavioral development up to 18 months of age. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Prostaglandins, Leukotrienes and Essential Fatty Acids
volume
86
issue
4-5
pages
183 - 188
publisher
Elsevier
external identifiers
  • wos:000304380600007
  • scopus:84860331615
ISSN
0952-3278
DOI
10.1016/j.plefa.2012.02.008
language
English
LU publication?
yes
id
9b1fd421-01de-4cc1-8917-299b80e3db76 (old id 2431541)
date added to LUP
2012-04-13 15:39:04
date last changed
2017-04-09 03:11:43
@article{9b1fd421-01de-4cc1-8917-299b80e3db76,
  abstract     = {The objective of this study was to investigate any association between infants' early development and PUFA concentrations in early breast milk and infants' plasma phospholipids at 44 weeks gestational age. Fifty-one premature infants were included. The quality of general movement was assessed at 3 months, and motor, mental and behavioral development at 3, 6, 10 and 18 months corrected age using Bayley's Scales of Infant Development (BSID-II). Linoleic acid, the major n-6/n-3 FA ratios, Mead acid and the EFA deficiency index in early breast milk were negatively associated with development up to 18 months of age. DHA and AA, respectively, in infants' plasma phospholipids was positively, but the AA/DHA ratio negatively, associated with development from 6 to 18 months of age. Our data suggest that the commonly found high n-6 concentration in breast milk is associated with less favorable motor, mental and behavioral development up to 18 months of age.},
  author       = {Sabel, K-G and Strandvik, B and Petzold, M and Lundqvist, Cristina},
  issn         = {0952-3278},
  language     = {eng},
  number       = {4-5},
  pages        = {183--188},
  publisher    = {Elsevier},
  series       = {Prostaglandins, Leukotrienes and Essential Fatty Acids},
  title        = {Motor, mental and behavioral developments in infancy are associated with fatty acid pattern in breast milk and plasma of premature infants.},
  url          = {http://dx.doi.org/10.1016/j.plefa.2012.02.008},
  volume       = {86},
  year         = {2012},
}