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Small Randomized Trial Among Low-Birth-Weight Children Receiving Bacillus Calmette-Guerin Vaccination First Health Center Contact

Biering-Sorensen, Sofie; Aaby, Peter; Napirna, Bitiguida Mutna; Roth, Adam LU ; Ravn, Henrik; Rodrigues, Amabelia; Whittle, Hilton and Benn, Christine Stabell (2012) In Pediatric Infectious Disease Journal 31(3). p.306-308
Abstract
A total of 105 low-birth-weight children presenting for first vaccination were randomized to receive bacillus Calmette-Guerin (BCG) immediately or later (current practice). The mortality rate ratio for BCG was 0.17 (95% CI = 0.02-1.35) within 3 days of enrollment, 0.28 (0.06-1.37) in the first month, and 0.27 (0.07-0.98) after 2 months of age. The mortality rate ratio was 0.41 (0.14-1.18) (P = 0.098) in infancy. Administration of BCG vaccine at first contact may contribute to lower mortality.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
vaccines, nonspecific effects of, neonatal mortality, infant mortality, BCG
in
Pediatric Infectious Disease Journal
volume
31
issue
3
pages
306 - 308
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000300706700021
  • pmid:22189537
  • scopus:84857526533
ISSN
1532-0987
DOI
10.1097/INF.0b013e3182458289
language
English
LU publication?
yes
id
679384bf-7240-4041-9211-91b2ddcfc7fe (old id 2510277)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22189537?dopt=Abstract
date added to LUP
2012-05-07 14:06:46
date last changed
2017-11-12 03:09:52
@article{679384bf-7240-4041-9211-91b2ddcfc7fe,
  abstract     = {A total of 105 low-birth-weight children presenting for first vaccination were randomized to receive bacillus Calmette-Guerin (BCG) immediately or later (current practice). The mortality rate ratio for BCG was 0.17 (95% CI = 0.02-1.35) within 3 days of enrollment, 0.28 (0.06-1.37) in the first month, and 0.27 (0.07-0.98) after 2 months of age. The mortality rate ratio was 0.41 (0.14-1.18) (P = 0.098) in infancy. Administration of BCG vaccine at first contact may contribute to lower mortality.},
  author       = {Biering-Sorensen, Sofie and Aaby, Peter and Napirna, Bitiguida Mutna and Roth, Adam and Ravn, Henrik and Rodrigues, Amabelia and Whittle, Hilton and Benn, Christine Stabell},
  issn         = {1532-0987},
  keyword      = {vaccines,nonspecific effects of,neonatal mortality,infant mortality,BCG},
  language     = {eng},
  number       = {3},
  pages        = {306--308},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Pediatric Infectious Disease Journal},
  title        = {Small Randomized Trial Among Low-Birth-Weight Children Receiving Bacillus Calmette-Guerin Vaccination First Health Center Contact},
  url          = {http://dx.doi.org/10.1097/INF.0b013e3182458289},
  volume       = {31},
  year         = {2012},
}