A unique 3D endoanal ultrasound feature of perianal Crohn's fistula:the "Crohn ultrasound fistula sign" (CUFS).
(2012) In Colorectal Disease 14(9). p.608-611- Abstract
- Aim: Using a high-resolution 3D endoanal ultrasound, we have observed that some perianal fistulas show a hypoechogenic fistula tract surrounded by a well-defined hyperechogenic area with a thin hypoechogenic edge outside characterized fistulas in patients with Crohn's disease ("Crohn's Ultrasound Fistula Sign" (CUFS)), unlike conventional fistula tracks.. The study aimed to determine the prevalence of CUFS in a consecutive series of patients with anal fistula. Method: 157 patients (median age 45, range 14-86 years,100 males) with perianal fistula were examined with 3D endoanal ultrasound. All 3D volumes were stored and analysed retrospectively by two independent observers blinded to the clinical information of the patients. Results: There... (More)
- Aim: Using a high-resolution 3D endoanal ultrasound, we have observed that some perianal fistulas show a hypoechogenic fistula tract surrounded by a well-defined hyperechogenic area with a thin hypoechogenic edge outside characterized fistulas in patients with Crohn's disease ("Crohn's Ultrasound Fistula Sign" (CUFS)), unlike conventional fistula tracks.. The study aimed to determine the prevalence of CUFS in a consecutive series of patients with anal fistula. Method: 157 patients (median age 45, range 14-86 years,100 males) with perianal fistula were examined with 3D endoanal ultrasound. All 3D volumes were stored and analysed retrospectively by two independent observers blinded to the clinical information of the patients. Results: There were 29 patients with Crohn's disease of whom 20 (69%) showed CUFS,. CUFS was absent in 125 (98%) of 128 patients without Crohn's disease. The positive and negative predictive value of CUFS for Crohn's disease was 87% and 93%, respectively. The kappa value of the two independent observers was 0.77, indicating a substantial interobserver agreement. Conclusion: This study provides a new 3D endoanal ultrasound criterion, CUFS, of perianal fistula in patients with Crohn's disease. The sign can be used to discriminate a Crohn's from other types of fistula, which may be useful in the management of patients with anal fistula. © 2012 The Authors Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2519375
- author
- Zawadzki, Antoni LU ; Starck-Söndergaard, Marianne LU ; Bohe, Måns LU and Thorlacius, Henrik LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- perianal fistula, Crohn's disease, 3D ultrasound
- in
- Colorectal Disease
- volume
- 14
- issue
- 9
- pages
- 608 - 611
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000307847000014
- pmid:22507755
- scopus:84865418011
- pmid:22507755
- ISSN
- 1462-8910
- DOI
- 10.1111/j.1463-1318.2012.03047.x
- language
- English
- LU publication?
- yes
- id
- e4624bf8-1706-416f-ab56-88567008384b (old id 2519375)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22507755?dopt=Abstract
- date added to LUP
- 2016-04-01 09:49:53
- date last changed
- 2022-01-25 17:07:22
@article{e4624bf8-1706-416f-ab56-88567008384b, abstract = {{Aim: Using a high-resolution 3D endoanal ultrasound, we have observed that some perianal fistulas show a hypoechogenic fistula tract surrounded by a well-defined hyperechogenic area with a thin hypoechogenic edge outside characterized fistulas in patients with Crohn's disease ("Crohn's Ultrasound Fistula Sign" (CUFS)), unlike conventional fistula tracks.. The study aimed to determine the prevalence of CUFS in a consecutive series of patients with anal fistula. Method: 157 patients (median age 45, range 14-86 years,100 males) with perianal fistula were examined with 3D endoanal ultrasound. All 3D volumes were stored and analysed retrospectively by two independent observers blinded to the clinical information of the patients. Results: There were 29 patients with Crohn's disease of whom 20 (69%) showed CUFS,. CUFS was absent in 125 (98%) of 128 patients without Crohn's disease. The positive and negative predictive value of CUFS for Crohn's disease was 87% and 93%, respectively. The kappa value of the two independent observers was 0.77, indicating a substantial interobserver agreement. Conclusion: This study provides a new 3D endoanal ultrasound criterion, CUFS, of perianal fistula in patients with Crohn's disease. The sign can be used to discriminate a Crohn's from other types of fistula, which may be useful in the management of patients with anal fistula. © 2012 The Authors Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.}}, author = {{Zawadzki, Antoni and Starck-Söndergaard, Marianne and Bohe, Måns and Thorlacius, Henrik}}, issn = {{1462-8910}}, keywords = {{perianal fistula; Crohn's disease; 3D ultrasound}}, language = {{eng}}, number = {{9}}, pages = {{608--611}}, publisher = {{Wiley-Blackwell}}, series = {{Colorectal Disease}}, title = {{A unique 3D endoanal ultrasound feature of perianal Crohn's fistula:the "Crohn ultrasound fistula sign" (CUFS).}}, url = {{http://dx.doi.org/10.1111/j.1463-1318.2012.03047.x}}, doi = {{10.1111/j.1463-1318.2012.03047.x}}, volume = {{14}}, year = {{2012}}, }