Occupational exposure to whole-body vibrations and pregnancy complications : A nationwide cohort study in Sweden
Skröder, Helena ; Pettersson, Hans ; Albin, Maria LU ; Gustavsson, Per ; Rylander, Lars LU
; Norlén, Filip
and Selander, Jenny
(2020)
In Occupational and environmental medicine
77(10).
p.691-698
- Abstract
Objectives Pregnancy complications are common contributors to perinatal mortality and morbidity. Still, the cause(s) of gestational hypertensive disorders and diabetes are largely unknown. Some occupational exposures have been inconsistently associated with pregnancy complications, but exposure to whole-body vibrations (WBV) has been largely overlooked even though it has been associated with adverse birth outcomes. Therefore, the aim was to assess whether occupational WBV exposure during pregnancy is associated with pregnancy complications in a nationwide, prospective cohort study. Methods The Fetal Air Pollution Exposure cohort was formed by merging multiple Swedish, national registers containing information on occupation during... (More)
Objectives Pregnancy complications are common contributors to perinatal mortality and morbidity. Still, the cause(s) of gestational hypertensive disorders and diabetes are largely unknown. Some occupational exposures have been inconsistently associated with pregnancy complications, but exposure to whole-body vibrations (WBV) has been largely overlooked even though it has been associated with adverse birth outcomes. Therefore, the aim was to assess whether occupational WBV exposure during pregnancy is associated with pregnancy complications in a nationwide, prospective cohort study. Methods The Fetal Air Pollution Exposure cohort was formed by merging multiple Swedish, national registers containing information on occupation during pregnancy and diagnosis codes, and includes all working women who gave birth between 1994 and 2014 (n=1 091 044). WBV exposure was derived from a job-exposure matrix and was divided into categories (0, 0.1-0.2, 0.3-0.4 and ≥0.5 m/s 2). ORs with 95% CIs were calculated using logistic regression adjusted for potential confounders. Results Among women working full time (n=646 490), we found increased risks of all pregnancy complications in the highest exposure group (≥0.5 m/s 2), compared with the lowest. The adjusted ORs were 1.76 (95% CI 1.41 to 2.20), 1.55 (95% CI 1.26 to 1.91) and 1.62 (95% CI 1.07 to 2.46) for preeclampsia, gestational hypertension and gestational diabetes, respectively, and were similar in all sensitivity analyses. There were no clear associations for part-time workers. Conclusions The results suggest that women should not be exposed to WBV at/above the action limit value of 0.5 m/s 2 (European directive) continuously through pregnancy. However, these results need further confirmation.
(Less)
- author
- Skröder, Helena
; Pettersson, Hans
; Albin, Maria
LU
; Gustavsson, Per
; Rylander, Lars
LU
; Norlén, Filip
and Selander, Jenny
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- epidemiology, female reproductive effects and adverse pregnancy outcomes, hygiene / occupational hygiene, vibration
- in
- Occupational and environmental medicine
- volume
- 77
- issue
- 10
- pages
- 8 pages
- publisher
- BMJ Publishing Group
- external identifiers
-
- scopus:85089945166
- pmid:32493701
- ISSN
- 1351-0711
- DOI
- 10.1136/oemed-2020-106519
- language
- English
- LU publication?
- yes
- id
- 25456589-ea3d-4cf2-afb2-871ec1d66c61
- date added to LUP
- 2021-01-08 12:02:21
- date last changed
- 2024-05-30 03:05:34
@article{25456589-ea3d-4cf2-afb2-871ec1d66c61,
abstract = {{<p>Objectives Pregnancy complications are common contributors to perinatal mortality and morbidity. Still, the cause(s) of gestational hypertensive disorders and diabetes are largely unknown. Some occupational exposures have been inconsistently associated with pregnancy complications, but exposure to whole-body vibrations (WBV) has been largely overlooked even though it has been associated with adverse birth outcomes. Therefore, the aim was to assess whether occupational WBV exposure during pregnancy is associated with pregnancy complications in a nationwide, prospective cohort study. Methods The Fetal Air Pollution Exposure cohort was formed by merging multiple Swedish, national registers containing information on occupation during pregnancy and diagnosis codes, and includes all working women who gave birth between 1994 and 2014 (n=1 091 044). WBV exposure was derived from a job-exposure matrix and was divided into categories (0, 0.1-0.2, 0.3-0.4 and ≥0.5 m/s 2). ORs with 95% CIs were calculated using logistic regression adjusted for potential confounders. Results Among women working full time (n=646 490), we found increased risks of all pregnancy complications in the highest exposure group (≥0.5 m/s 2), compared with the lowest. The adjusted ORs were 1.76 (95% CI 1.41 to 2.20), 1.55 (95% CI 1.26 to 1.91) and 1.62 (95% CI 1.07 to 2.46) for preeclampsia, gestational hypertension and gestational diabetes, respectively, and were similar in all sensitivity analyses. There were no clear associations for part-time workers. Conclusions The results suggest that women should not be exposed to WBV at/above the action limit value of 0.5 m/s 2 (European directive) continuously through pregnancy. However, these results need further confirmation. </p>}},
author = {{Skröder, Helena and Pettersson, Hans and Albin, Maria and Gustavsson, Per and Rylander, Lars and Norlén, Filip and Selander, Jenny}},
issn = {{1351-0711}},
keywords = {{epidemiology; female reproductive effects and adverse pregnancy outcomes; hygiene / occupational hygiene; vibration}},
language = {{eng}},
number = {{10}},
pages = {{691--698}},
publisher = {{BMJ Publishing Group}},
series = {{Occupational and environmental medicine}},
title = {{Occupational exposure to whole-body vibrations and pregnancy complications : A nationwide cohort study in Sweden}},
url = {{http://dx.doi.org/10.1136/oemed-2020-106519}},
doi = {{10.1136/oemed-2020-106519}},
volume = {{77}},
year = {{2020}},
}