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Prognosis of cerebral vein thrombosis presenting as isolated headache: Early vs. late diagnosis

Gameiro, Joana; Ferro, Jose M.; Canhao, Patricia; Stam, Jan; Barinagarrementeria, Fernando and Lindgren, Arne LU (2012) In Cephalalgia 32(5). p.407-412
Abstract
Objective: To analyse the outcome of cerebral venous thrombosis (CVT) patients presenting with isolated headache, specifically to compare isolated headache patients with early vs. late CVT diagnosis. Method: In the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) database we compared the outcome of patients with isolated headache and a CVT diagnosed early (<= 7 days from onset) vs. late (> 7 days). We retrieved 100 patients with isolated headache, 52 patients with early CVT diagnosis (early isolated headache) and 48 with late CVT diagnosis (late isolated headache). Results: Neurological worsening was more frequent within early isolated headache patients (23% vs. 8%) (p = 0.045). At the last follow-up (median... (More)
Objective: To analyse the outcome of cerebral venous thrombosis (CVT) patients presenting with isolated headache, specifically to compare isolated headache patients with early vs. late CVT diagnosis. Method: In the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) database we compared the outcome of patients with isolated headache and a CVT diagnosed early (<= 7 days from onset) vs. late (> 7 days). We retrieved 100 patients with isolated headache, 52 patients with early CVT diagnosis (early isolated headache) and 48 with late CVT diagnosis (late isolated headache). Results: Neurological worsening was more frequent within early isolated headache patients (23% vs. 8%) (p = 0.045). At the last follow-up (median 411 days), 93% patients had a complete recovery, and 4% were dead or dependent, with no significant difference between early isolated headache and late isolated headache. Conclusion: The outcome of CVT patients with isolated headache diagnosed early or late was similarly favourable, but there was a higher proportion of neurological worsening in the acute phase among early isolated headache patients, who need close neurological monitoring. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Symptomatic headache, cerebral venous thrombosis, dural sinus, prognosis
in
Cephalalgia
volume
32
issue
5
pages
407 - 412
publisher
Wiley-Blackwell
external identifiers
  • wos:000303065700008
  • scopus:84860176575
ISSN
0333-1024
DOI
10.1177/0333102412439353
language
English
LU publication?
yes
id
f830629b-1b8e-490f-a698-de19f5fc9dab (old id 2570325)
date added to LUP
2012-06-01 08:50:49
date last changed
2017-08-20 03:56:09
@article{f830629b-1b8e-490f-a698-de19f5fc9dab,
  abstract     = {Objective: To analyse the outcome of cerebral venous thrombosis (CVT) patients presenting with isolated headache, specifically to compare isolated headache patients with early vs. late CVT diagnosis. Method: In the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) database we compared the outcome of patients with isolated headache and a CVT diagnosed early (&lt;= 7 days from onset) vs. late (&gt; 7 days). We retrieved 100 patients with isolated headache, 52 patients with early CVT diagnosis (early isolated headache) and 48 with late CVT diagnosis (late isolated headache). Results: Neurological worsening was more frequent within early isolated headache patients (23% vs. 8%) (p = 0.045). At the last follow-up (median 411 days), 93% patients had a complete recovery, and 4% were dead or dependent, with no significant difference between early isolated headache and late isolated headache. Conclusion: The outcome of CVT patients with isolated headache diagnosed early or late was similarly favourable, but there was a higher proportion of neurological worsening in the acute phase among early isolated headache patients, who need close neurological monitoring.},
  author       = {Gameiro, Joana and Ferro, Jose M. and Canhao, Patricia and Stam, Jan and Barinagarrementeria, Fernando and Lindgren, Arne},
  issn         = {0333-1024},
  keyword      = {Symptomatic headache,cerebral venous thrombosis,dural sinus,prognosis},
  language     = {eng},
  number       = {5},
  pages        = {407--412},
  publisher    = {Wiley-Blackwell},
  series       = {Cephalalgia},
  title        = {Prognosis of cerebral vein thrombosis presenting as isolated headache: Early vs. late diagnosis},
  url          = {http://dx.doi.org/10.1177/0333102412439353},
  volume       = {32},
  year         = {2012},
}