Standard Guidelines for the Chromosome-Centric Human Proteome Project
(2012) In Journal of Proteome Research 11(4). p.2005-2013- Abstract
- The objective of the international Chromosome-Centric Human Proteome Project (C-HPP) is to map and annotate all proteins encoded by the genes on each human chromosome. The C-FIPP consortium was established to organize a collaborative network among the research teams responsible for protein mapping of individual chromosomes and to identify compelling biological and genetic mechanisms influencing colocated genes and their protein products. The C-HPP aims to foster the development of proteome analysis and integration of the findings from related molecular -omics technology platforms through collaborations among universities, industries, and private research groups. The C-HPP consortium leadership has elicited broad input for standard... (More)
- The objective of the international Chromosome-Centric Human Proteome Project (C-HPP) is to map and annotate all proteins encoded by the genes on each human chromosome. The C-FIPP consortium was established to organize a collaborative network among the research teams responsible for protein mapping of individual chromosomes and to identify compelling biological and genetic mechanisms influencing colocated genes and their protein products. The C-HPP aims to foster the development of proteome analysis and integration of the findings from related molecular -omics technology platforms through collaborations among universities, industries, and private research groups. The C-HPP consortium leadership has elicited broad input for standard guidelines to manage these international efforts more efficiently by mobilizing existing resources and collaborative networks. The C-HPP guidelines set out the collaborative consensus of the C-HPP teams, introduce topics associated with experimental approaches, data production, quality control, treatment, and transparency of data, governance of the consortium, and collaborative benefits. A companion approach for the Biology and Disease-Driven HPP (B/D-HPP) component of the Human Proteome Project is currently being organized, building upon the Human Proteome Organization's organ-based and biofluid-based initiatives (www.hupo.org/research). The common application of these guidelines in the participating laboratories is expected to facilitate the goal of a comprehensive analysis of the human proteome. (Less)
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https://lup.lub.lu.se/record/2587736
- author
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- antibody, Biology/Disease-Driven Human Proteome Project, Chromosome-Centric Human Proteome Project, Human Genome Project, Human, Proteome Project, Human Proteome Organization, knowledge-base, mass, spectrometry
- in
- Journal of Proteome Research
- volume
- 11
- issue
- 4
- pages
- 2005 - 2013
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000302388100001
- scopus:84859622404
- pmid:22443261
- ISSN
- 1535-3893
- DOI
- 10.1021/pr200824a
- language
- English
- LU publication?
- yes
- id
- c8bd2452-0966-4124-b995-eef3ae4c8ede (old id 2587736)
- date added to LUP
- 2016-04-01 10:28:07
- date last changed
- 2022-03-12 06:08:07
@article{c8bd2452-0966-4124-b995-eef3ae4c8ede,
abstract = {{The objective of the international Chromosome-Centric Human Proteome Project (C-HPP) is to map and annotate all proteins encoded by the genes on each human chromosome. The C-FIPP consortium was established to organize a collaborative network among the research teams responsible for protein mapping of individual chromosomes and to identify compelling biological and genetic mechanisms influencing colocated genes and their protein products. The C-HPP aims to foster the development of proteome analysis and integration of the findings from related molecular -omics technology platforms through collaborations among universities, industries, and private research groups. The C-HPP consortium leadership has elicited broad input for standard guidelines to manage these international efforts more efficiently by mobilizing existing resources and collaborative networks. The C-HPP guidelines set out the collaborative consensus of the C-HPP teams, introduce topics associated with experimental approaches, data production, quality control, treatment, and transparency of data, governance of the consortium, and collaborative benefits. A companion approach for the Biology and Disease-Driven HPP (B/D-HPP) component of the Human Proteome Project is currently being organized, building upon the Human Proteome Organization's organ-based and biofluid-based initiatives (www.hupo.org/research). The common application of these guidelines in the participating laboratories is expected to facilitate the goal of a comprehensive analysis of the human proteome.}},
author = {{Paik, Young-Ki and Omenn, Gilbert S. and Uhlen, Mathias and Hanash, Samir and Marko-Varga, György and Aebersold, Ruedi and Bairoch, Amos and Yamamoto, Tadashi and Legrain, Pierre and Lee, Hyoung-Joo and Na, Keun and Jeong, Seul-Ki and He, Fuchu and Binz, Pierre-Alain and Nishimura, Toshihide and Keown, Paul and Baker, Mark S. and Yoo, Jong Shin and Garin, Jerome and Archakov, Alexander and Bergeron, John and Salekdeh, Ghasem Hosseini and Hancock, William S.}},
issn = {{1535-3893}},
keywords = {{antibody; Biology/Disease-Driven Human Proteome Project; Chromosome-Centric Human Proteome Project; Human Genome Project; Human; Proteome Project; Human Proteome Organization; knowledge-base; mass; spectrometry}},
language = {{eng}},
number = {{4}},
pages = {{2005--2013}},
publisher = {{The American Chemical Society (ACS)}},
series = {{Journal of Proteome Research}},
title = {{Standard Guidelines for the Chromosome-Centric Human Proteome Project}},
url = {{http://dx.doi.org/10.1021/pr200824a}},
doi = {{10.1021/pr200824a}},
volume = {{11}},
year = {{2012}},
}