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A 4-Year Exercise Program in Children Increases Bone Mass Without Increasing Fracture Risk.

Löfgren, Bjarne LU ; Dencker, Magnus LU ; Nilsson, Jan-Åke LU and Karlsson, Magnus LU (2012) In Pediatrics 129(6). p.1468-1476
Abstract
BACKGROUND:

Most prospective pediatric exercise intervention studies cover <1 year and use bone traits as surrogate end points for fractures. This prospective controlled exercise intervention study therefore followed not only skeletal development but also fracture incidence for 4 years.



METHODS:

Fractures were prospectively registered in a cohort of children aged 7 to 9 years, 446 boys and 362 girls in the intervention group (2675 person-years) and 807 boys and 780 girls in the control group (5661 person-years). The intervention included 40 minutes per day of school physical education for 4 years whereas the controls had 60 minutes per week. In a subsample, 73 boys and 48 girls in the intervention... (More)
BACKGROUND:

Most prospective pediatric exercise intervention studies cover <1 year and use bone traits as surrogate end points for fractures. This prospective controlled exercise intervention study therefore followed not only skeletal development but also fracture incidence for 4 years.



METHODS:

Fractures were prospectively registered in a cohort of children aged 7 to 9 years, 446 boys and 362 girls in the intervention group (2675 person-years) and 807 boys and 780 girls in the control group (5661 person-years). The intervention included 40 minutes per day of school physical education for 4 years whereas the controls had 60 minutes per week. In a subsample, 73 boys and 48 girls in the intervention and 52 boys and 48 girls in the control group, bone mineral content (g) and bone width (cm) were followed by means of dual-energy radiograph absorptiometry.



RESULTS:

The rate ratio for fractures was 1.11. In the dual-energy radiograph absorptiometry-measured children, there were no group differences at baseline in age, anthropometrics, or bone traits. The mean annual gain in lumbar spine bone mineral content was 7.0% higher in girls and 3.3% higher in boys and in femoral neck width 1.7% higher in girls and 0.6% higher in boys in the intervention than in the control group.



CONCLUSIONS:

A population-based moderately intense 4-year exercise program in 7- to 9-year-old children increased bone mass and size without affecting the fracture risk. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pediatrics
volume
129
issue
6
pages
1468 - 1476
publisher
American Academy of Pediatrics
external identifiers
  • wos:000304707000013
  • pmid:22641757
  • scopus:84861917483
ISSN
1098-4275
DOI
10.1542/peds.2011-2274
language
English
LU publication?
yes
id
e645657e-b530-4c11-a798-3779901b029e (old id 2608348)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22641757?dopt=Abstract
date added to LUP
2012-06-04 20:58:28
date last changed
2017-05-21 04:38:34
@article{e645657e-b530-4c11-a798-3779901b029e,
  abstract     = {BACKGROUND:<br/><br>
Most prospective pediatric exercise intervention studies cover &lt;1 year and use bone traits as surrogate end points for fractures. This prospective controlled exercise intervention study therefore followed not only skeletal development but also fracture incidence for 4 years.<br/><br>
<br/><br>
METHODS:<br/><br>
Fractures were prospectively registered in a cohort of children aged 7 to 9 years, 446 boys and 362 girls in the intervention group (2675 person-years) and 807 boys and 780 girls in the control group (5661 person-years). The intervention included 40 minutes per day of school physical education for 4 years whereas the controls had 60 minutes per week. In a subsample, 73 boys and 48 girls in the intervention and 52 boys and 48 girls in the control group, bone mineral content (g) and bone width (cm) were followed by means of dual-energy radiograph absorptiometry.<br/><br>
<br/><br>
RESULTS:<br/><br>
The rate ratio for fractures was 1.11. In the dual-energy radiograph absorptiometry-measured children, there were no group differences at baseline in age, anthropometrics, or bone traits. The mean annual gain in lumbar spine bone mineral content was 7.0% higher in girls and 3.3% higher in boys and in femoral neck width 1.7% higher in girls and 0.6% higher in boys in the intervention than in the control group.<br/><br>
<br/><br>
CONCLUSIONS:<br/><br>
A population-based moderately intense 4-year exercise program in 7- to 9-year-old children increased bone mass and size without affecting the fracture risk.},
  author       = {Löfgren, Bjarne and Dencker, Magnus and Nilsson, Jan-Åke and Karlsson, Magnus},
  issn         = {1098-4275},
  language     = {eng},
  number       = {6},
  pages        = {1468--1476},
  publisher    = {American Academy of Pediatrics},
  series       = {Pediatrics},
  title        = {A 4-Year Exercise Program in Children Increases Bone Mass Without Increasing Fracture Risk.},
  url          = {http://dx.doi.org/10.1542/peds.2011-2274},
  volume       = {129},
  year         = {2012},
}