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Do leukotrienes increase cell viability in human intestinal epithelial cells?

Öhd, John F LU ; Wikström, Katarina LU and Sjölander, Anita LU (2002) In Advances in Experimental Medicine and Biology 507. p.8-193
Abstract

In this preliminary report we present data showing that leukotrienes increase the baseline cell viability in human intestinal epithelial cells and that LTB4 partially reverses the morphological hallmarks of non-necrotic cell death induced by the COX-2 specific inhibitor NS-398. The proposed signaling mechanisms regulating these events are summarized in fig. 3. Please view the work on LT signal transduction in these cells by Thodeti et al. in this volume.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Cell Line, Cell Survival/drug effects, Cyclooxygenase Inhibitors/pharmacology, Humans, Intestinal Mucosa/cytology, Leukotrienes/physiology, Nitrobenzenes/pharmacology, Sulfonamides/pharmacology
host publication
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5
series title
Advances in Experimental Medicine and Biology
editor
Honn, K ; Marnett, L ; Nigam, S ; Dennis, E and Serhan, C
volume
507
pages
8 - 193
publisher
Springer
external identifiers
  • pmid:12664585
ISSN
0065-2598
ISBN
978-1-4615-0193-0
DOI
10.1007/978-1-4615-0193-0_30
language
English
LU publication?
yes
id
26596cdf-4715-42c3-9a9d-d2d59bf2793b
date added to LUP
2019-07-03 11:37:23
date last changed
2021-12-02 16:43:21
@inbook{26596cdf-4715-42c3-9a9d-d2d59bf2793b,
  abstract     = {{<p>In this preliminary report we present data showing that leukotrienes increase the baseline cell viability in human intestinal epithelial cells and that LTB4 partially reverses the morphological hallmarks of non-necrotic cell death induced by the COX-2 specific inhibitor NS-398. The proposed signaling mechanisms regulating these events are summarized in fig. 3. Please view the work on LT signal transduction in these cells by Thodeti et al. in this volume.</p>}},
  author       = {{Öhd, John F and Wikström, Katarina and Sjölander, Anita}},
  booktitle    = {{Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5}},
  editor       = {{Honn, K and Marnett, L and Nigam, S and Dennis, E and Serhan, C}},
  isbn         = {{978-1-4615-0193-0}},
  issn         = {{0065-2598}},
  keywords     = {{Cell Line; Cell Survival/drug effects; Cyclooxygenase Inhibitors/pharmacology; Humans; Intestinal Mucosa/cytology; Leukotrienes/physiology; Nitrobenzenes/pharmacology; Sulfonamides/pharmacology}},
  language     = {{eng}},
  pages        = {{8--193}},
  publisher    = {{Springer}},
  series       = {{Advances in Experimental Medicine and Biology}},
  title        = {{Do leukotrienes increase cell viability in human intestinal epithelial cells?}},
  url          = {{http://dx.doi.org/10.1007/978-1-4615-0193-0_30}},
  doi          = {{10.1007/978-1-4615-0193-0_30}},
  volume       = {{507}},
  year         = {{2002}},
}