Malaria and Helminthic Co-Infection during Pregnancy in Sub-Saharan Africa : A Systematic Review and Meta-Analysis
(2022) In International Journal of Environmental Research and Public Health 19(9).- Abstract
Malaria and helminthic co-infection during pregnancy causes fetomaternal haemorrhage and foetal growth retardation. This study determined the pooled burden of pregnancy malaria and helminthic co-infection in sub-Saharan Africa. CINAHL, EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were used to retrieve data from the literature, without restricting language and publication year. The Joanna Briggs Institute’s critical appraisal tool for prevalence studies was used for quality assessment. STATA Version 14.0 was used to conduct the meta-analysis. The I2 statistics and Egger’s test were used to test heterogeneity and publication bias. The random-effects model was used to estimate the pooled prevalence at a... (More)
Malaria and helminthic co-infection during pregnancy causes fetomaternal haemorrhage and foetal growth retardation. This study determined the pooled burden of pregnancy malaria and helminthic co-infection in sub-Saharan Africa. CINAHL, EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were used to retrieve data from the literature, without restricting language and publication year. The Joanna Briggs Institute’s critical appraisal tool for prevalence studies was used for quality assessment. STATA Version 14.0 was used to conduct the meta-analysis. The I2 statistics and Egger’s test were used to test heterogeneity and publication bias. The random-effects model was used to estimate the pooled prevalence at a 95% confidence interval (CI). The review protocol has been registered in PROSPERO, with the number CRD42019144812. In total, 24 studies (n = 14,087 participants) were identified in this study. The pooled analysis revealed that 20% of pregnant women were co-infected by malaria and helminths in sub-Saharan Africa. The pooled prevalence of malaria and helminths were 33% and 35%, respectively. The most prevalent helminths were Hookworm (48%), Ascaris lumbricoides (37%), and Trichuris trichiura (15%). Significantly higher malaria and helminthic co-infection during pregnancy were observed. Health systems in sub-Saharan Africa must implement home-grown innovative solutions to underpin context-specific policies for the early initiation of effective intermittent preventive therapy.
(Less)
- author
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- co-infection, comorbidity, helminthic infections, pregnancy malaria, sub-Saharan Africa
- in
- International Journal of Environmental Research and Public Health
- volume
- 19
- issue
- 9
- article number
- 5444
- publisher
- MDPI AG
- external identifiers
-
- scopus:85129114862
- pmid:35564842
- ISSN
- 1661-7827
- DOI
- 10.3390/ijerph19095444
- language
- English
- LU publication?
- yes
- id
- 2690a356-2a90-418a-bda4-34974914ccbd
- date added to LUP
- 2022-07-04 14:34:52
- date last changed
- 2024-06-09 21:18:26
@article{2690a356-2a90-418a-bda4-34974914ccbd,
abstract = {{<p>Malaria and helminthic co-infection during pregnancy causes fetomaternal haemorrhage and foetal growth retardation. This study determined the pooled burden of pregnancy malaria and helminthic co-infection in sub-Saharan Africa. CINAHL, EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were used to retrieve data from the literature, without restricting language and publication year. The Joanna Briggs Institute’s critical appraisal tool for prevalence studies was used for quality assessment. STATA Version 14.0 was used to conduct the meta-analysis. The I<sup>2</sup> statistics and Egger’s test were used to test heterogeneity and publication bias. The random-effects model was used to estimate the pooled prevalence at a 95% confidence interval (CI). The review protocol has been registered in PROSPERO, with the number CRD42019144812. In total, 24 studies (n = 14,087 participants) were identified in this study. The pooled analysis revealed that 20% of pregnant women were co-infected by malaria and helminths in sub-Saharan Africa. The pooled prevalence of malaria and helminths were 33% and 35%, respectively. The most prevalent helminths were Hookworm (48%), Ascaris lumbricoides (37%), and Trichuris trichiura (15%). Significantly higher malaria and helminthic co-infection during pregnancy were observed. Health systems in sub-Saharan Africa must implement home-grown innovative solutions to underpin context-specific policies for the early initiation of effective intermittent preventive therapy.</p>}},
author = {{Boltena, Minyahil Tadesse and El-Khatib, Ziad and Kebede, Abraham Sahilemichael and Asamoah, Benedict Oppong and Yaw, Appiah Seth Christopher and Kamara, Kassim and Assogba, Phénix Constant and Boltena, Andualem Tadesse and Adane, Hawult Taye and Hailemeskel, Elifaged and Biru, Mulatu}},
issn = {{1661-7827}},
keywords = {{co-infection; comorbidity; helminthic infections; pregnancy malaria; sub-Saharan Africa}},
language = {{eng}},
number = {{9}},
publisher = {{MDPI AG}},
series = {{International Journal of Environmental Research and Public Health}},
title = {{Malaria and Helminthic Co-Infection during Pregnancy in Sub-Saharan Africa : A Systematic Review and Meta-Analysis}},
url = {{http://dx.doi.org/10.3390/ijerph19095444}},
doi = {{10.3390/ijerph19095444}},
volume = {{19}},
year = {{2022}},
}