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Age- and time-dependent changes in cancer incidence among immigrants to Sweden: colorectal, lung, breast and prostate cancers

Mousavi, Seyed Mohsen; Fallah, Mahdi; Sundquist, Kristina LU and Hemminki, Kari LU (2012) In International Journal of Cancer 131(2). p.122-128
Abstract
To examine the role of gender, age at immigration and length of stay on incidence trends of common cancers, we studied risk of colorectal, lung, breast and prostate cancers in immigrants to Sweden from 1958 to 2008. The nationwide Swedish Family-Cancer Database was used to calculate standardized incidence ratios for common cancers among immigrants compared to Swedes. Immigrants were classified into high-risk countries when their risk was increased, into low-risk when their risk was decreased and into other when their risk was nonsignificant. Among those who immigrated at younger age (<30 years), we found an increasing trend for colorectal cancer risk in low-risk men and high-risk women. Among those who immigrated at older age (=30... (More)
To examine the role of gender, age at immigration and length of stay on incidence trends of common cancers, we studied risk of colorectal, lung, breast and prostate cancers in immigrants to Sweden from 1958 to 2008. The nationwide Swedish Family-Cancer Database was used to calculate standardized incidence ratios for common cancers among immigrants compared to Swedes. Immigrants were classified into high-risk countries when their risk was increased, into low-risk when their risk was decreased and into other when their risk was nonsignificant. Among those who immigrated at younger age (<30 years), we found an increasing trend for colorectal cancer risk in low-risk men and high-risk women. Among those who immigrated at older age (=30 years), a decreasing lung cancer risk in high-risk men and an increasing breast cancer risk in low-risk women were observed. The increasing trend of prostate cancer risk was independent of age at immigration. The risk trends for other immigrants were between the risks of low- and high-risk countries. The gender-specific shifts in cancer risks in immigrants toward the risk in natives indicate a major role of sex, age at immigration and environmental exposures in colorectal and lung cancers risks. In contrast, the unchanged trend of breast cancer among those who immigrated at younger ages and an increasing trend for those who migrated at older ages may suggest a limited effect for environmental exposures, especially at younger age. Our study points out a role of age at immigration on the risk trend of cancer. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cancer, colorectal, breast, immigrants, lung, prostate, risks, Sweden, trends
in
International Journal of Cancer
volume
131
issue
2
pages
122 - 128
publisher
John Wiley & Sons
external identifiers
  • wos:000304350600013
  • scopus:84861586909
ISSN
0020-7136
DOI
10.1002/ijc.27334
language
English
LU publication?
yes
id
715fb7e7-980d-4627-93cf-0af7838acf18 (old id 2799566)
date added to LUP
2012-07-03 10:24:44
date last changed
2017-10-22 03:29:06
@article{715fb7e7-980d-4627-93cf-0af7838acf18,
  abstract     = {To examine the role of gender, age at immigration and length of stay on incidence trends of common cancers, we studied risk of colorectal, lung, breast and prostate cancers in immigrants to Sweden from 1958 to 2008. The nationwide Swedish Family-Cancer Database was used to calculate standardized incidence ratios for common cancers among immigrants compared to Swedes. Immigrants were classified into high-risk countries when their risk was increased, into low-risk when their risk was decreased and into other when their risk was nonsignificant. Among those who immigrated at younger age (&lt;30 years), we found an increasing trend for colorectal cancer risk in low-risk men and high-risk women. Among those who immigrated at older age (=30 years), a decreasing lung cancer risk in high-risk men and an increasing breast cancer risk in low-risk women were observed. The increasing trend of prostate cancer risk was independent of age at immigration. The risk trends for other immigrants were between the risks of low- and high-risk countries. The gender-specific shifts in cancer risks in immigrants toward the risk in natives indicate a major role of sex, age at immigration and environmental exposures in colorectal and lung cancers risks. In contrast, the unchanged trend of breast cancer among those who immigrated at younger ages and an increasing trend for those who migrated at older ages may suggest a limited effect for environmental exposures, especially at younger age. Our study points out a role of age at immigration on the risk trend of cancer.},
  author       = {Mousavi, Seyed Mohsen and Fallah, Mahdi and Sundquist, Kristina and Hemminki, Kari},
  issn         = {0020-7136},
  keyword      = {cancer,colorectal,breast,immigrants,lung,prostate,risks,Sweden,trends},
  language     = {eng},
  number       = {2},
  pages        = {122--128},
  publisher    = {John Wiley & Sons},
  series       = {International Journal of Cancer},
  title        = {Age- and time-dependent changes in cancer incidence among immigrants to Sweden: colorectal, lung, breast and prostate cancers},
  url          = {http://dx.doi.org/10.1002/ijc.27334},
  volume       = {131},
  year         = {2012},
}