European practice patterns for antiplatelet management in NSTE-ACS patients : Results from the REal-world ADoption survey focus on Acute antiPlatelet Treatment (READAPT) survey
(2023) In International Journal of Cardiology 386. p.8-16- Abstract
Background: The 2020 European Society of Cardiology (ESC) guidelines for the diagnosis and management of patients with non-ST elevation-acute coronary syndrome (NSTE-ACS) recommend early invasive coronary angiography in high-risk patients and no routine pre-treatment with oral P2Y12 receptor inhibitor in NSTE-ACS patients prior to defining coronary anatomy. Objective: To assess the implementation of this recommendation in the real-life setting. Methods: A web-survey in 17 European countries collected physician profiles and their perceptions of the diagnosis, medical and invasive management of NSTE-ACS patients at their hospital. A sample size of at least 1100 responders permitted the estimation of proportions with a precision of at... (More)
Background: The 2020 European Society of Cardiology (ESC) guidelines for the diagnosis and management of patients with non-ST elevation-acute coronary syndrome (NSTE-ACS) recommend early invasive coronary angiography in high-risk patients and no routine pre-treatment with oral P2Y12 receptor inhibitor in NSTE-ACS patients prior to defining coronary anatomy. Objective: To assess the implementation of this recommendation in the real-life setting. Methods: A web-survey in 17 European countries collected physician profiles and their perceptions of the diagnosis, medical and invasive management of NSTE-ACS patients at their hospital. A sample size of at least 1100 responders permitted the estimation of proportions with a precision of at least ±3.0%. Results: Among the 3024 targeted participants, 1154 provided valid feedback defined as a 50% response rate of answers to the survey questions. Overall, >60% of the participants declared full implementation of the guidelines at their institution. The time delay from admission to coronary angiography and PCI was reported to be <24 h in over 75% of the hospitals while pre-treatment was intended in >50% of NSTE-ACS patients. Ad-hoc percutaneous coronary intervention (PCI) was performed in >70% of the cases while intravenous platelet inhibition was rarely used (<10%). Between countries differences in practice patterns for antiplatelet management for NSTE-ACS were observed, suggesting heterogeneous implementation of the guidelines. Conclusions: This survey indicates that the implementation of 2020 NSTE-ACS guidelines on early invasive management and pre-treatment is heterogeneous, potentially due by local logistical constraints.
(Less)
- author
- Angiolillo, Dominick J. ; Erlinge, David LU ; Ferreiro, José Luis ; Gale, Chris P. ; Huber, Kurt ; Musumeci, Giuseppe and Collet, Jean Philippe
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Guidelines, NSTE-ACS, P2Y12 receptor inhibitors, PCI
- in
- International Journal of Cardiology
- volume
- 386
- pages
- 9 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:37201617
- scopus:85160418318
- ISSN
- 0167-5273
- DOI
- 10.1016/j.ijcard.2023.05.025
- language
- English
- LU publication?
- yes
- id
- 2804255b-cdb1-4faa-bc78-3aa758c9017e
- date added to LUP
- 2023-08-15 12:19:21
- date last changed
- 2024-04-20 01:37:24
@article{2804255b-cdb1-4faa-bc78-3aa758c9017e, abstract = {{<p>Background: The 2020 European Society of Cardiology (ESC) guidelines for the diagnosis and management of patients with non-ST elevation-acute coronary syndrome (NSTE-ACS) recommend early invasive coronary angiography in high-risk patients and no routine pre-treatment with oral P2Y12 receptor inhibitor in NSTE-ACS patients prior to defining coronary anatomy. Objective: To assess the implementation of this recommendation in the real-life setting. Methods: A web-survey in 17 European countries collected physician profiles and their perceptions of the diagnosis, medical and invasive management of NSTE-ACS patients at their hospital. A sample size of at least 1100 responders permitted the estimation of proportions with a precision of at least ±3.0%. Results: Among the 3024 targeted participants, 1154 provided valid feedback defined as a 50% response rate of answers to the survey questions. Overall, >60% of the participants declared full implementation of the guidelines at their institution. The time delay from admission to coronary angiography and PCI was reported to be <24 h in over 75% of the hospitals while pre-treatment was intended in >50% of NSTE-ACS patients. Ad-hoc percutaneous coronary intervention (PCI) was performed in >70% of the cases while intravenous platelet inhibition was rarely used (<10%). Between countries differences in practice patterns for antiplatelet management for NSTE-ACS were observed, suggesting heterogeneous implementation of the guidelines. Conclusions: This survey indicates that the implementation of 2020 NSTE-ACS guidelines on early invasive management and pre-treatment is heterogeneous, potentially due by local logistical constraints.</p>}}, author = {{Angiolillo, Dominick J. and Erlinge, David and Ferreiro, José Luis and Gale, Chris P. and Huber, Kurt and Musumeci, Giuseppe and Collet, Jean Philippe}}, issn = {{0167-5273}}, keywords = {{Guidelines; NSTE-ACS; P2Y12 receptor inhibitors; PCI}}, language = {{eng}}, pages = {{8--16}}, publisher = {{Elsevier}}, series = {{International Journal of Cardiology}}, title = {{European practice patterns for antiplatelet management in NSTE-ACS patients : Results from the REal-world ADoption survey focus on Acute antiPlatelet Treatment (READAPT) survey}}, url = {{http://dx.doi.org/10.1016/j.ijcard.2023.05.025}}, doi = {{10.1016/j.ijcard.2023.05.025}}, volume = {{386}}, year = {{2023}}, }