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Ultrasonic agitation in microchannels

Bengtsson, Martin LU and Laurell, Thomas LU (2004) In Analytical and Bioanalytical Chemistry 378(7). p.1716-1721
Abstract
This paper describes an acoustic method for inducing rotating vortex flows in microchannels. An ultrasonic crystal is used to create an acoustic standing wave field in the channel and thus induce a Rayleigh flow transverse to the laminar flow in the channel. Mixing in microchannels is strictly diffusion-limited because of the laminar flow, a transverse flow will greatly enhance mixing of the reactants. This is especially evident in chemical microsystems in which the chemical reaction is performed on a solid phase and only one reactant is actually diffusing. The method has been evaluated on two different systems, a mixing channel with two parallel flows and a porous silicon micro enzyme reactor for protein digestion. In both systems a... (More)
This paper describes an acoustic method for inducing rotating vortex flows in microchannels. An ultrasonic crystal is used to create an acoustic standing wave field in the channel and thus induce a Rayleigh flow transverse to the laminar flow in the channel. Mixing in microchannels is strictly diffusion-limited because of the laminar flow, a transverse flow will greatly enhance mixing of the reactants. This is especially evident in chemical microsystems in which the chemical reaction is performed on a solid phase and only one reactant is actually diffusing. The method has been evaluated on two different systems, a mixing channel with two parallel flows and a porous silicon micro enzyme reactor for protein digestion. In both systems a significant increase of the mixing ratio is detected in a narrow band of frequency for the actuating ultrasound. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
acoustics, Rayleigh flow, microchannels, rotating vortex flow, ultrasonic agitation, reagent mixing
in
Analytical and Bioanalytical Chemistry
volume
378
issue
7
pages
1716 - 1721
publisher
Springer
external identifiers
  • wos:000220458400009
  • pmid:14689151
  • scopus:21144436524
ISSN
1618-2642
DOI
10.1007/s00216-003-2334-y
language
English
LU publication?
yes
id
67efbbfa-fc1a-4218-8cdd-606c211eb0c9 (old id 284124)
date added to LUP
2007-10-17 08:17:45
date last changed
2017-09-24 03:36:47
@article{67efbbfa-fc1a-4218-8cdd-606c211eb0c9,
  abstract     = {This paper describes an acoustic method for inducing rotating vortex flows in microchannels. An ultrasonic crystal is used to create an acoustic standing wave field in the channel and thus induce a Rayleigh flow transverse to the laminar flow in the channel. Mixing in microchannels is strictly diffusion-limited because of the laminar flow, a transverse flow will greatly enhance mixing of the reactants. This is especially evident in chemical microsystems in which the chemical reaction is performed on a solid phase and only one reactant is actually diffusing. The method has been evaluated on two different systems, a mixing channel with two parallel flows and a porous silicon micro enzyme reactor for protein digestion. In both systems a significant increase of the mixing ratio is detected in a narrow band of frequency for the actuating ultrasound.},
  author       = {Bengtsson, Martin and Laurell, Thomas},
  issn         = {1618-2642},
  keyword      = {acoustics,Rayleigh flow,microchannels,rotating vortex flow,ultrasonic agitation,reagent mixing},
  language     = {eng},
  number       = {7},
  pages        = {1716--1721},
  publisher    = {Springer},
  series       = {Analytical and Bioanalytical Chemistry},
  title        = {Ultrasonic agitation in microchannels},
  url          = {http://dx.doi.org/10.1007/s00216-003-2334-y},
  volume       = {378},
  year         = {2004},
}