Determination of optical scattering properties of highly-scattering media in optical coherence tomography images
(2004) In Optics Express 12(2). p.249-259- Abstract
- We developed a new algorithm that fits optical coherence tomography (OCT) signals as a function of depth to a general theoretical OCT model which takes into account multiple scattering effects. With use of this algorithm, it was possible to extract both the scattering coefficient and anisotropy factor from a particular region of interest in an OCT image. The extraction algorithm was evaluated against measurements from an integrating sphere on a set of tissue phantoms and yielded valid results. Finally, a preliminary ex vivo OCT investigation on human aortic specimen indicated that the algorithm may contribute importantly to differentiation between normal and atherosclerotic arteries. We conclude that this algorithm may facilitate tissue... (More)
- We developed a new algorithm that fits optical coherence tomography (OCT) signals as a function of depth to a general theoretical OCT model which takes into account multiple scattering effects. With use of this algorithm, it was possible to extract both the scattering coefficient and anisotropy factor from a particular region of interest in an OCT image. The extraction algorithm was evaluated against measurements from an integrating sphere on a set of tissue phantoms and yielded valid results. Finally, a preliminary ex vivo OCT investigation on human aortic specimen indicated that the algorithm may contribute importantly to differentiation between normal and atherosclerotic arteries. We conclude that this algorithm may facilitate tissue characterization by OCT. (C) 2004 Optical Society of America. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/288578
- author
- Levitz, D ; Thrane, L ; Frosz, MH ; Andersen, PE ; Andersen, CB ; Valanciunaite, J ; Swartling, Johannes LU ; Andersson-Engels, Stefan LU and Hansen, PR
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Optics Express
- volume
- 12
- issue
- 2
- pages
- 249 - 259
- publisher
- Optical Society of America
- external identifiers
-
- wos:000188383200003
- scopus:1942487924
- ISSN
- 1094-4087
- language
- English
- LU publication?
- yes
- id
- 7dffa0d1-14ab-4fbb-8b70-8581bff488a5 (old id 288578)
- alternative location
- http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-2-249
- date added to LUP
- 2016-04-01 15:41:19
- date last changed
- 2022-01-28 06:33:05
@article{7dffa0d1-14ab-4fbb-8b70-8581bff488a5, abstract = {{We developed a new algorithm that fits optical coherence tomography (OCT) signals as a function of depth to a general theoretical OCT model which takes into account multiple scattering effects. With use of this algorithm, it was possible to extract both the scattering coefficient and anisotropy factor from a particular region of interest in an OCT image. The extraction algorithm was evaluated against measurements from an integrating sphere on a set of tissue phantoms and yielded valid results. Finally, a preliminary ex vivo OCT investigation on human aortic specimen indicated that the algorithm may contribute importantly to differentiation between normal and atherosclerotic arteries. We conclude that this algorithm may facilitate tissue characterization by OCT. (C) 2004 Optical Society of America.}}, author = {{Levitz, D and Thrane, L and Frosz, MH and Andersen, PE and Andersen, CB and Valanciunaite, J and Swartling, Johannes and Andersson-Engels, Stefan and Hansen, PR}}, issn = {{1094-4087}}, language = {{eng}}, number = {{2}}, pages = {{249--259}}, publisher = {{Optical Society of America}}, series = {{Optics Express}}, title = {{Determination of optical scattering properties of highly-scattering media in optical coherence tomography images}}, url = {{https://lup.lub.lu.se/search/files/4449584/2370333.pdf}}, volume = {{12}}, year = {{2004}}, }