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A Contemporary Update on Pathology Reporting for Prostate Cancer: Biopsy and Radical Prostatectomy Specimens

Fine, Samson W.; Amin, Mahul B.; Berney, Daniel M.; Bjartell, Anders LU ; Egevad, Lars; Epstein, Jonathan I.; Humphrey, Peter A.; Magi-Galluzzi, Christina; Montironi, Rodolfo and Stief, Christian (2012) In European Urology 62(1). p.20-39
Abstract
Context: The diagnosis of and reporting parameters for prostate cancer (PCa) have evolved over time, yet they remain key components in predicting clinical outcomes. Objective: Update pathology reporting standards for PCa. Evidence acquisition: A thorough literature review was performed for articles discussing PCa handling, grading, staging, and reporting published as of September 15, 2011. Electronic articles published ahead of print were also considered. Proceedings of recent international conferences addressing these areas were extensively reviewed. Evidence synthesis: Two main areas of reporting were examined: (1) prostatic needle biopsy, including handling, contemporary Gleason grading, extent of involvement, and high-risk... (More)
Context: The diagnosis of and reporting parameters for prostate cancer (PCa) have evolved over time, yet they remain key components in predicting clinical outcomes. Objective: Update pathology reporting standards for PCa. Evidence acquisition: A thorough literature review was performed for articles discussing PCa handling, grading, staging, and reporting published as of September 15, 2011. Electronic articles published ahead of print were also considered. Proceedings of recent international conferences addressing these areas were extensively reviewed. Evidence synthesis: Two main areas of reporting were examined: (1) prostatic needle biopsy, including handling, contemporary Gleason grading, extent of involvement, and high-risk lesions/precursors and (2) radical prostatectomy (RP), including sectioning, multifocality, Gleason grading, staging of organ-confined and extraprostatic disease, lymph node involvement, tumor volume, and lymphovascular invasion. For each category, consensus views, controversial areas, and clinical import were reviewed. Conclusions: Modern prostate needle biopsy and RP reports are extremely detailed so as to maximize clinical utility. Accurate diagnosis of cancer-specific features requires up-to-date knowledge of grading, quantitation, and staging criteria. While some areas remain controversial, efforts to codify existing knowledge have had a significant impact on pathology practice. (C) 2012 European Association of Urology. Published by Elsevier B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Gleason grading, Needle biopsy, Prostate cancer, Radical prostatectomy, Reporting, Staging
in
European Urology
volume
62
issue
1
pages
20 - 39
publisher
Elsevier
external identifiers
  • wos:000304487900018
  • scopus:84861599138
ISSN
1873-7560
DOI
10.1016/j.eururo.2012.02.055
language
English
LU publication?
yes
id
5398d4a2-78b9-47db-b6ee-db9ea5e26f74 (old id 2906413)
date added to LUP
2012-08-01 09:45:59
date last changed
2017-11-05 03:56:58
@article{5398d4a2-78b9-47db-b6ee-db9ea5e26f74,
  abstract     = {Context: The diagnosis of and reporting parameters for prostate cancer (PCa) have evolved over time, yet they remain key components in predicting clinical outcomes. Objective: Update pathology reporting standards for PCa. Evidence acquisition: A thorough literature review was performed for articles discussing PCa handling, grading, staging, and reporting published as of September 15, 2011. Electronic articles published ahead of print were also considered. Proceedings of recent international conferences addressing these areas were extensively reviewed. Evidence synthesis: Two main areas of reporting were examined: (1) prostatic needle biopsy, including handling, contemporary Gleason grading, extent of involvement, and high-risk lesions/precursors and (2) radical prostatectomy (RP), including sectioning, multifocality, Gleason grading, staging of organ-confined and extraprostatic disease, lymph node involvement, tumor volume, and lymphovascular invasion. For each category, consensus views, controversial areas, and clinical import were reviewed. Conclusions: Modern prostate needle biopsy and RP reports are extremely detailed so as to maximize clinical utility. Accurate diagnosis of cancer-specific features requires up-to-date knowledge of grading, quantitation, and staging criteria. While some areas remain controversial, efforts to codify existing knowledge have had a significant impact on pathology practice. (C) 2012 European Association of Urology. Published by Elsevier B.V. All rights reserved.},
  author       = {Fine, Samson W. and Amin, Mahul B. and Berney, Daniel M. and Bjartell, Anders and Egevad, Lars and Epstein, Jonathan I. and Humphrey, Peter A. and Magi-Galluzzi, Christina and Montironi, Rodolfo and Stief, Christian},
  issn         = {1873-7560},
  keyword      = {Gleason grading,Needle biopsy,Prostate cancer,Radical prostatectomy,Reporting,Staging},
  language     = {eng},
  number       = {1},
  pages        = {20--39},
  publisher    = {Elsevier},
  series       = {European Urology},
  title        = {A Contemporary Update on Pathology Reporting for Prostate Cancer: Biopsy and Radical Prostatectomy Specimens},
  url          = {http://dx.doi.org/10.1016/j.eururo.2012.02.055},
  volume       = {62},
  year         = {2012},
}