A method for MR quantification of flow velocities in blood and CSF using interleaved gradient-echo pulse sequences
(1989) In Magnetic Resonance Imaging 7(6). p.655-667- Abstract
The aim of this study was to establish a rapid method for in vivo quantification of a large range of flow velocities using phase information. A basic gradient-echo sequence was constructed, in which flow was encoded along the slice selection direction by variation of the amplitude of a bipolar gradient without changes in sequence timings. The influence of field inhomogeneities and eddy currents was studied in a 1.5 T scanner. From the basic sequence, interleaved sequences for calibration and in vivo flow determination were constructed, and flow information was obtained by pairwise subtraction of velocity-encoded from velocity non-encoded phase images. Calibration was performed in a nongated mode using flow phantoms, and the results were... (More)
The aim of this study was to establish a rapid method for in vivo quantification of a large range of flow velocities using phase information. A basic gradient-echo sequence was constructed, in which flow was encoded along the slice selection direction by variation of the amplitude of a bipolar gradient without changes in sequence timings. The influence of field inhomogeneities and eddy currents was studied in a 1.5 T scanner. From the basic sequence, interleaved sequences for calibration and in vivo flow determination were constructed, and flow information was obtained by pairwise subtraction of velocity-encoded from velocity non-encoded phase images. Calibration was performed in a nongated mode using flow phantoms, and the results were compared with theoretically calculated encoding efficiencies. In vivo flow was studied in healthy volunteers in three different areas using cardiac gating; central blood flow in the great thoracic vessels, peripheral blood flow in the popliteal vessels, and flow of cerebrospinal fluid (CSF) in the cerebral aqueduct. The results show good agreement with results obtained with other techniques. The proposed method for flow determination was shown to be rapid and flexible, and we thus conclude that it seems well suited for routine clinical MR examinations.
(Less)
- author
- organization
- publishing date
- 1989-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Blood, CSF, Flow, Gradient echo, MR, Phase image, Quantification
- in
- Magnetic Resonance Imaging
- volume
- 7
- issue
- 6
- pages
- 13 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:2698430
- scopus:0024948220
- ISSN
- 0730-725X
- DOI
- 10.1016/0730-725X(89)90535-3
- language
- English
- LU publication?
- yes
- id
- 2910d1d6-88e3-482b-b6a8-23fedbda5530
- date added to LUP
- 2020-05-16 12:56:01
- date last changed
- 2024-01-02 11:00:58
@article{2910d1d6-88e3-482b-b6a8-23fedbda5530, abstract = {{<p>The aim of this study was to establish a rapid method for in vivo quantification of a large range of flow velocities using phase information. A basic gradient-echo sequence was constructed, in which flow was encoded along the slice selection direction by variation of the amplitude of a bipolar gradient without changes in sequence timings. The influence of field inhomogeneities and eddy currents was studied in a 1.5 T scanner. From the basic sequence, interleaved sequences for calibration and in vivo flow determination were constructed, and flow information was obtained by pairwise subtraction of velocity-encoded from velocity non-encoded phase images. Calibration was performed in a nongated mode using flow phantoms, and the results were compared with theoretically calculated encoding efficiencies. In vivo flow was studied in healthy volunteers in three different areas using cardiac gating; central blood flow in the great thoracic vessels, peripheral blood flow in the popliteal vessels, and flow of cerebrospinal fluid (CSF) in the cerebral aqueduct. The results show good agreement with results obtained with other techniques. The proposed method for flow determination was shown to be rapid and flexible, and we thus conclude that it seems well suited for routine clinical MR examinations.</p>}}, author = {{Ståhlberg, Freddy and Mogelvang, Jens and Thomsen, Carsten and Nordell, Bo and Stubgaard, Max and Ericsson, Anders and Sperber, Göran and Greitz, Dan and Larsson, Henrik and Henriksen, Ole and Persson, Bertil}}, issn = {{0730-725X}}, keywords = {{Blood; CSF; Flow; Gradient echo; MR; Phase image; Quantification}}, language = {{eng}}, month = {{01}}, number = {{6}}, pages = {{655--667}}, publisher = {{Elsevier}}, series = {{Magnetic Resonance Imaging}}, title = {{A method for MR quantification of flow velocities in blood and CSF using interleaved gradient-echo pulse sequences}}, url = {{http://dx.doi.org/10.1016/0730-725X(89)90535-3}}, doi = {{10.1016/0730-725X(89)90535-3}}, volume = {{7}}, year = {{1989}}, }