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Interstitial laser coagulation versus transurethral resection of the prostate for benign prostatic enlargement - A prospective Randomized study

Liedberg, Fredrik LU ; Adell, L; Hagberg, G and Palmqvist, IB (2003) In Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00 37(6). p.494-497
Abstract
Objective: Interstitial laser coagulation (ILC) of the prostate is a minimally invasive method for treating symptomatic benign prostatic enlargement (BPE). We performed a prospective randomized study to compare the clinical outcomes of ILC and transurethral resection of the prostate (TURP). Material and Methods: Between December 1997 and February 2000, 38 patients with moderate-to-severe symptomatic BPE were included in the study. Seven were subsequently excluded due to intercurrent disease or protocol violation and the remaining 31 were randomized to either TURP (n = 11) or ILC (n = 20). A suprapubic tube was inserted in all ILC-treated patients, and ILC was performed as an outpatient procedure when feasible. Data were recorded... (More)
Objective: Interstitial laser coagulation (ILC) of the prostate is a minimally invasive method for treating symptomatic benign prostatic enlargement (BPE). We performed a prospective randomized study to compare the clinical outcomes of ILC and transurethral resection of the prostate (TURP). Material and Methods: Between December 1997 and February 2000, 38 patients with moderate-to-severe symptomatic BPE were included in the study. Seven were subsequently excluded due to intercurrent disease or protocol violation and the remaining 31 were randomized to either TURP (n = 11) or ILC (n = 20). A suprapubic tube was inserted in all ILC-treated patients, and ILC was performed as an outpatient procedure when feasible. Data were recorded preoperatively and at 3-month and 1-year follow-up. The assessment parameters were International Prostate Symptom Score (IPSS), uroflow, prostate volume determined by means of transrectal ultrasound and postvoid residue. Results: At 1-year follow-up, uroflowmetry indicated a more pronounced increase in peak urinary flow rate (Q(max) ) in the TURP patients than in the ILC subjects (p < 0.02). Differences in postvoid residue, IPSS and prostate volume between the two treatments could not be evaluated due to the small number of patients in each group. Postoperative urinary tract infections occurred in 13 ILC patients but in only one TURP subject, and catheterization was done for 24 days after ILC and for 2 days after TURP. The study was ended prematurely due to the prolonged postoperative catheterization and the high rate of urinary tract infections in the ILC patients. Conclusions: At 1-year follow-up, the increase in Q(max) was smaller in the ILC subjects than in the TURP patients. The ILC subjects had comparatively more postoperative urinary tract infections and more prolonged postoperative catheterization than the TURP patients. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
transurethral resection of the prostate, benign prostatic enlargement, interstitial laser coagulation
in
Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00
volume
37
issue
6
pages
494 - 497
publisher
Taylor & Francis
external identifiers
  • wos:000187296700009
  • pmid:14675923
  • scopus:0345865048
ISSN
0036-5599
DOI
10.1080/00365590310001773
language
English
LU publication?
yes
id
09b3833f-24c7-431e-98c5-2c955cbae52c (old id 292278)
date added to LUP
2007-09-16 12:22:09
date last changed
2018-05-29 09:53:06
@article{09b3833f-24c7-431e-98c5-2c955cbae52c,
  abstract     = {Objective: Interstitial laser coagulation (ILC) of the prostate is a minimally invasive method for treating symptomatic benign prostatic enlargement (BPE). We performed a prospective randomized study to compare the clinical outcomes of ILC and transurethral resection of the prostate (TURP). Material and Methods: Between December 1997 and February 2000, 38 patients with moderate-to-severe symptomatic BPE were included in the study. Seven were subsequently excluded due to intercurrent disease or protocol violation and the remaining 31 were randomized to either TURP (n = 11) or ILC (n = 20). A suprapubic tube was inserted in all ILC-treated patients, and ILC was performed as an outpatient procedure when feasible. Data were recorded preoperatively and at 3-month and 1-year follow-up. The assessment parameters were International Prostate Symptom Score (IPSS), uroflow, prostate volume determined by means of transrectal ultrasound and postvoid residue. Results: At 1-year follow-up, uroflowmetry indicated a more pronounced increase in peak urinary flow rate (Q(max) ) in the TURP patients than in the ILC subjects (p &lt; 0.02). Differences in postvoid residue, IPSS and prostate volume between the two treatments could not be evaluated due to the small number of patients in each group. Postoperative urinary tract infections occurred in 13 ILC patients but in only one TURP subject, and catheterization was done for 24 days after ILC and for 2 days after TURP. The study was ended prematurely due to the prolonged postoperative catheterization and the high rate of urinary tract infections in the ILC patients. Conclusions: At 1-year follow-up, the increase in Q(max) was smaller in the ILC subjects than in the TURP patients. The ILC subjects had comparatively more postoperative urinary tract infections and more prolonged postoperative catheterization than the TURP patients.},
  author       = {Liedberg, Fredrik and Adell, L and Hagberg, G and Palmqvist, IB},
  issn         = {0036-5599},
  keyword      = {transurethral resection of the prostate,benign prostatic enlargement,interstitial laser coagulation},
  language     = {eng},
  number       = {6},
  pages        = {494--497},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00},
  title        = {Interstitial laser coagulation versus transurethral resection of the prostate for benign prostatic enlargement - A prospective Randomized study},
  url          = {http://dx.doi.org/10.1080/00365590310001773},
  volume       = {37},
  year         = {2003},
}