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Carbon dioxide rebreathing with the anaesthetic conserving device, AnaConDa

Walther Sturesson, Louise LU ; Malmkvist, Gunnar LU ; Bodelsson, Mikael LU ; Niklason, Lisbet LU and Jonson, Björn LU (2012) In British Journal of Anaesthesia 109(2). p.279-283
Abstract
The anaesthetic conserving device (ACD) AnaConDa was developed to allow the reduced use of inhaled agents by conserving exhaled agent and allowing rebreathing. Elevated has been observed in patients when using this ACD, despite tidal volume compensation for the larger apparatus dead space. The aim of the present study was to determine whether CO2, like inhaled anaesthetics, adsorbs to the ACD during expiration and returns to a test lung during the following inspiration. The ACD was attached to an experimental test lung. Apparent dead space by the single-breath test for CO2 and the amount of CO2 adsorbed to the carbon filter of the ACD was measured with infrared spectrometry. Apparent dead space was 230 ml larger using the ACD compared with... (More)
The anaesthetic conserving device (ACD) AnaConDa was developed to allow the reduced use of inhaled agents by conserving exhaled agent and allowing rebreathing. Elevated has been observed in patients when using this ACD, despite tidal volume compensation for the larger apparatus dead space. The aim of the present study was to determine whether CO2, like inhaled anaesthetics, adsorbs to the ACD during expiration and returns to a test lung during the following inspiration. The ACD was attached to an experimental test lung. Apparent dead space by the single-breath test for CO2 and the amount of CO2 adsorbed to the carbon filter of the ACD was measured with infrared spectrometry. Apparent dead space was 230 ml larger using the ACD compared with a conventional heat and moisture exchanger (internal volumes 100 and 50 ml, respectively). Varying CO2 flux to the test lung (85375 ml min(1)) did not change the measured dead space nor did varying respiratory rate (1224 bpm). The ACD contained 3.3 times more CO2 than the predicted amount present in its internal volume of 100 ml. Our measurements show a CO2 reservoir effect of 180 ml in excess of the ACD internal volume. This is due to adsorption of CO2 in the ACD during expiration and return of CO2 during the following inspiration. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
airway, dead space, anaesthetic techniques, inhalation, carbon dioxide, rebreathing, equipment, heatmoisture exchanger
in
British Journal of Anaesthesia
volume
109
issue
2
pages
279 - 283
publisher
Elsevier
external identifiers
  • wos:000306363900023
  • scopus:84863951797
ISSN
1471-6771
DOI
10.1093/bja/aes102
language
English
LU publication?
yes
id
b11bc778-4202-4fde-964b-01b50327e8c3 (old id 2994840)
date added to LUP
2016-04-01 11:12:57
date last changed
2022-04-28 08:06:40
@article{b11bc778-4202-4fde-964b-01b50327e8c3,
  abstract     = {{The anaesthetic conserving device (ACD) AnaConDa was developed to allow the reduced use of inhaled agents by conserving exhaled agent and allowing rebreathing. Elevated has been observed in patients when using this ACD, despite tidal volume compensation for the larger apparatus dead space. The aim of the present study was to determine whether CO2, like inhaled anaesthetics, adsorbs to the ACD during expiration and returns to a test lung during the following inspiration. The ACD was attached to an experimental test lung. Apparent dead space by the single-breath test for CO2 and the amount of CO2 adsorbed to the carbon filter of the ACD was measured with infrared spectrometry. Apparent dead space was 230 ml larger using the ACD compared with a conventional heat and moisture exchanger (internal volumes 100 and 50 ml, respectively). Varying CO2 flux to the test lung (85375 ml min(1)) did not change the measured dead space nor did varying respiratory rate (1224 bpm). The ACD contained 3.3 times more CO2 than the predicted amount present in its internal volume of 100 ml. Our measurements show a CO2 reservoir effect of 180 ml in excess of the ACD internal volume. This is due to adsorption of CO2 in the ACD during expiration and return of CO2 during the following inspiration.}},
  author       = {{Walther Sturesson, Louise and Malmkvist, Gunnar and Bodelsson, Mikael and Niklason, Lisbet and Jonson, Björn}},
  issn         = {{1471-6771}},
  keywords     = {{airway; dead space; anaesthetic techniques; inhalation; carbon dioxide; rebreathing; equipment; heatmoisture exchanger}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{279--283}},
  publisher    = {{Elsevier}},
  series       = {{British Journal of Anaesthesia}},
  title        = {{Carbon dioxide rebreathing with the anaesthetic conserving device, AnaConDa}},
  url          = {{https://lup.lub.lu.se/search/files/2478485/3164722.pdf}},
  doi          = {{10.1093/bja/aes102}},
  volume       = {{109}},
  year         = {{2012}},
}