The impact of parenthood on risk of registration for alcohol use disorder in married individuals : A Swedish population-based analysis
(2019) In Psychological Medicine 49(13). p.2141-2148- Abstract
BackgroundAlthough being married with children is associated with a reduced rate of alcohol use disorder (AUD), is this finding independent of a marital effect, different in mothers and fathers and potentially causal in effect.MethodsUsing Cox proportional hazards, we examined, in 1 252 237 married individuals, the association between a resident younger and older child and risk for AUD registration in national medical, criminal, and pharmacy registers. Using logistic regression, we analyzed, in 600 219 parents, within-person models comparing risk for AUD prior to first pregnancy v. with young children. We examined whether risk for AUD in 1302 parents after a first spousal AUD registration was reduced by having a young resident... (More)
BackgroundAlthough being married with children is associated with a reduced rate of alcohol use disorder (AUD), is this finding independent of a marital effect, different in mothers and fathers and potentially causal in effect.MethodsUsing Cox proportional hazards, we examined, in 1 252 237 married individuals, the association between a resident younger and older child and risk for AUD registration in national medical, criminal, and pharmacy registers. Using logistic regression, we analyzed, in 600 219 parents, within-person models comparing risk for AUD prior to first pregnancy v. with young children. We examined whether risk for AUD in 1302 parents after a first spousal AUD registration was reduced by having a young resident child.ResultsCompared with childless married individuals, resident younger children were associated with a reduced risk for AUD in mothers [hazard ratio (HR) 0.36, 95% confidence interval 0.31-0.41] and fathers (HR 0.66, 0.60-0.73). The reduced risk was attenuated but still significant for older children. Within-person models confirmed the protective effect of young children in mothers [odds ratio (OR) 0.49, 0.30-0.80] but yielded inconclusive results in fathers (OR 0.85, 0.58-1.25). After a first spousal registration for AUD, a resident young child was associated with a substantial reduction in risk for mothers and a weaker marginal effect in fathers.ConclusionIn married individuals, resident children are associated with a reduction in basal risk for AUD which is stronger in mothers than fathers and with younger v. older children. This effect is also evident during high-risk periods. In mothers, our results are consistent with a largely causal effect.
(Less)
- author
- Kendler, Kenneth S. LU ; Larsson Lönn, Sara LU ; Salvatore, Jessica E. ; Sundquist, Jan LU and Sundquist, Kristina LU
- organization
- publishing date
- 2019-10
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Alcohol use disorder, children, epidemiology, marriage
- in
- Psychological Medicine
- volume
- 49
- issue
- 13
- pages
- 8 pages
- publisher
- Cambridge University Press
- external identifiers
-
- pmid:30355386
- scopus:85055552255
- ISSN
- 0033-2917
- DOI
- 10.1017/S0033291718002969
- language
- English
- LU publication?
- yes
- id
- 2c285396-2615-4794-9ee7-323a9cfae046
- date added to LUP
- 2018-12-10 14:27:09
- date last changed
- 2024-09-17 09:39:57
@article{2c285396-2615-4794-9ee7-323a9cfae046, abstract = {{<p>BackgroundAlthough being married with children is associated with a reduced rate of alcohol use disorder (AUD), is this finding independent of a marital effect, different in mothers and fathers and potentially causal in effect.MethodsUsing Cox proportional hazards, we examined, in 1 252 237 married individuals, the association between a resident younger and older child and risk for AUD registration in national medical, criminal, and pharmacy registers. Using logistic regression, we analyzed, in 600 219 parents, within-person models comparing risk for AUD prior to first pregnancy v. with young children. We examined whether risk for AUD in 1302 parents after a first spousal AUD registration was reduced by having a young resident child.ResultsCompared with childless married individuals, resident younger children were associated with a reduced risk for AUD in mothers [hazard ratio (HR) 0.36, 95% confidence interval 0.31-0.41] and fathers (HR 0.66, 0.60-0.73). The reduced risk was attenuated but still significant for older children. Within-person models confirmed the protective effect of young children in mothers [odds ratio (OR) 0.49, 0.30-0.80] but yielded inconclusive results in fathers (OR 0.85, 0.58-1.25). After a first spousal registration for AUD, a resident young child was associated with a substantial reduction in risk for mothers and a weaker marginal effect in fathers.ConclusionIn married individuals, resident children are associated with a reduction in basal risk for AUD which is stronger in mothers than fathers and with younger v. older children. This effect is also evident during high-risk periods. In mothers, our results are consistent with a largely causal effect.</p>}}, author = {{Kendler, Kenneth S. and Larsson Lönn, Sara and Salvatore, Jessica E. and Sundquist, Jan and Sundquist, Kristina}}, issn = {{0033-2917}}, keywords = {{Alcohol use disorder; children; epidemiology; marriage}}, language = {{eng}}, number = {{13}}, pages = {{2141--2148}}, publisher = {{Cambridge University Press}}, series = {{Psychological Medicine}}, title = {{The impact of parenthood on risk of registration for alcohol use disorder in married individuals : A Swedish population-based analysis}}, url = {{http://dx.doi.org/10.1017/S0033291718002969}}, doi = {{10.1017/S0033291718002969}}, volume = {{49}}, year = {{2019}}, }