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The impact of parenthood on risk of registration for alcohol use disorder in married individuals : A Swedish population-based analysis

Kendler, Kenneth S. LU ; Larsson Lönn, Sara LU ; Salvatore, Jessica E. ; Sundquist, Jan LU and Sundquist, Kristina LU (2019) In Psychological Medicine 49(13). p.2141-2148
Abstract

BackgroundAlthough being married with children is associated with a reduced rate of alcohol use disorder (AUD), is this finding independent of a marital effect, different in mothers and fathers and potentially causal in effect.MethodsUsing Cox proportional hazards, we examined, in 1 252 237 married individuals, the association between a resident younger and older child and risk for AUD registration in national medical, criminal, and pharmacy registers. Using logistic regression, we analyzed, in 600 219 parents, within-person models comparing risk for AUD prior to first pregnancy v. with young children. We examined whether risk for AUD in 1302 parents after a first spousal AUD registration was reduced by having a young resident... (More)

BackgroundAlthough being married with children is associated with a reduced rate of alcohol use disorder (AUD), is this finding independent of a marital effect, different in mothers and fathers and potentially causal in effect.MethodsUsing Cox proportional hazards, we examined, in 1 252 237 married individuals, the association between a resident younger and older child and risk for AUD registration in national medical, criminal, and pharmacy registers. Using logistic regression, we analyzed, in 600 219 parents, within-person models comparing risk for AUD prior to first pregnancy v. with young children. We examined whether risk for AUD in 1302 parents after a first spousal AUD registration was reduced by having a young resident child.ResultsCompared with childless married individuals, resident younger children were associated with a reduced risk for AUD in mothers [hazard ratio (HR) 0.36, 95% confidence interval 0.31-0.41] and fathers (HR 0.66, 0.60-0.73). The reduced risk was attenuated but still significant for older children. Within-person models confirmed the protective effect of young children in mothers [odds ratio (OR) 0.49, 0.30-0.80] but yielded inconclusive results in fathers (OR 0.85, 0.58-1.25). After a first spousal registration for AUD, a resident young child was associated with a substantial reduction in risk for mothers and a weaker marginal effect in fathers.ConclusionIn married individuals, resident children are associated with a reduction in basal risk for AUD which is stronger in mothers than fathers and with younger v. older children. This effect is also evident during high-risk periods. In mothers, our results are consistent with a largely causal effect.

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; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Alcohol use disorder, children, epidemiology, marriage
in
Psychological Medicine
volume
49
issue
13
pages
8 pages
publisher
Cambridge University Press
external identifiers
  • scopus:85055552255
  • pmid:30355386
ISSN
0033-2917
DOI
10.1017/S0033291718002969
language
English
LU publication?
yes
id
2c285396-2615-4794-9ee7-323a9cfae046
date added to LUP
2018-12-10 14:27:09
date last changed
2021-05-11 04:29:13
@article{2c285396-2615-4794-9ee7-323a9cfae046,
  abstract     = {<p>BackgroundAlthough being married with children is associated with a reduced rate of alcohol use disorder (AUD), is this finding independent of a marital effect, different in mothers and fathers and potentially causal in effect.MethodsUsing Cox proportional hazards, we examined, in 1 252 237 married individuals, the association between a resident younger and older child and risk for AUD registration in national medical, criminal, and pharmacy registers. Using logistic regression, we analyzed, in 600 219 parents, within-person models comparing risk for AUD prior to first pregnancy v. with young children. We examined whether risk for AUD in 1302 parents after a first spousal AUD registration was reduced by having a young resident child.ResultsCompared with childless married individuals, resident younger children were associated with a reduced risk for AUD in mothers [hazard ratio (HR) 0.36, 95% confidence interval 0.31-0.41] and fathers (HR 0.66, 0.60-0.73). The reduced risk was attenuated but still significant for older children. Within-person models confirmed the protective effect of young children in mothers [odds ratio (OR) 0.49, 0.30-0.80] but yielded inconclusive results in fathers (OR 0.85, 0.58-1.25). After a first spousal registration for AUD, a resident young child was associated with a substantial reduction in risk for mothers and a weaker marginal effect in fathers.ConclusionIn married individuals, resident children are associated with a reduction in basal risk for AUD which is stronger in mothers than fathers and with younger v. older children. This effect is also evident during high-risk periods. In mothers, our results are consistent with a largely causal effect.</p>},
  author       = {Kendler, Kenneth S. and Larsson Lönn, Sara and Salvatore, Jessica E. and Sundquist, Jan and Sundquist, Kristina},
  issn         = {0033-2917},
  language     = {eng},
  number       = {13},
  pages        = {2141--2148},
  publisher    = {Cambridge University Press},
  series       = {Psychological Medicine},
  title        = {The impact of parenthood on risk of registration for alcohol use disorder in married individuals : A Swedish population-based analysis},
  url          = {http://dx.doi.org/10.1017/S0033291718002969},
  doi          = {10.1017/S0033291718002969},
  volume       = {49},
  year         = {2019},
}