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Comparative study of antibacterial activity of pancreatic juice in six mammalian species

Pierzynowski, Stefan G. LU ; Sharma, Peeyush ; Sobczyk, Jerzy ; Garwacki, Stanislaw ; Barej, Wieslaw and Westrom, Bjorn LU (1993) In Pancreas 8(5). p.546-550
Abstract

A comparative study of antibacterial activity of pancreatic juice was conduced on six mammalian species. Pancreatic juice collections were conducted as acute (rabbit, guinea pig, rat) and chronic (pig, sheep, cattle) experiments, in the former before and after stimulation [cholecystokinin (CCK) and secretin] and in the latter under basal conditions alone. Antibacterial activity was tested on Micrococcus pyogenes and compared with that of neomycin. The samples were tested under normal conditions and after heating and dilution. The pancreatic juice of rat showed no activity against Micrococcus pyo-genes. The antibacterial activity of rabbit and guinea pig pancreatic juice under basal conditions was similar within the group but... (More)

A comparative study of antibacterial activity of pancreatic juice was conduced on six mammalian species. Pancreatic juice collections were conducted as acute (rabbit, guinea pig, rat) and chronic (pig, sheep, cattle) experiments, in the former before and after stimulation [cholecystokinin (CCK) and secretin] and in the latter under basal conditions alone. Antibacterial activity was tested on Micrococcus pyogenes and compared with that of neomycin. The samples were tested under normal conditions and after heating and dilution. The pancreatic juice of rat showed no activity against Micrococcus pyo-genes. The antibacterial activity of rabbit and guinea pig pancreatic juice under basal conditions was similar within the group but significantly higher than that of pig, sheep and cattle which also did not differ significantly within the group. On stimulation with CCK and secretin, no significant change could be observed in the potency of antimicrobial activity of pancreatic juice in the rabbit and guinea pig. The antibacterial activity remained unchanged after heating to 65°C and upon dilution to 1:10.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Antibacterial activity, Mammals, Micrococcus pyogenes, Neomycin, Pancreatic juice
in
Pancreas
volume
8
issue
5
pages
5 pages
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:8302790
  • scopus:0027326148
ISSN
0885-3177
DOI
10.1097/00006676-199309000-00003
language
English
LU publication?
yes
id
2c9b26a6-b9d2-457e-b794-cc7d69ce4758
date added to LUP
2024-12-05 15:22:41
date last changed
2025-04-04 15:03:31
@article{2c9b26a6-b9d2-457e-b794-cc7d69ce4758,
  abstract     = {{<p>A comparative study of antibacterial activity of pancreatic juice was conduced on six mammalian species. Pancreatic juice collections were conducted as acute (rabbit, guinea pig, rat) and chronic (pig, sheep, cattle) experiments, in the former before and after stimulation [cholecystokinin (CCK) and secretin] and in the latter under basal conditions alone. Antibacterial activity was tested on Micrococcus pyogenes and compared with that of neomycin. The samples were tested under normal conditions and after heating and dilution. The pancreatic juice of rat showed no activity against Micrococcus pyo-genes. The antibacterial activity of rabbit and guinea pig pancreatic juice under basal conditions was similar within the group but significantly higher than that of pig, sheep and cattle which also did not differ significantly within the group. On stimulation with CCK and secretin, no significant change could be observed in the potency of antimicrobial activity of pancreatic juice in the rabbit and guinea pig. The antibacterial activity remained unchanged after heating to 65°C and upon dilution to 1:10.</p>}},
  author       = {{Pierzynowski, Stefan G. and Sharma, Peeyush and Sobczyk, Jerzy and Garwacki, Stanislaw and Barej, Wieslaw and Westrom, Bjorn}},
  issn         = {{0885-3177}},
  keywords     = {{Antibacterial activity; Mammals; Micrococcus pyogenes; Neomycin; Pancreatic juice}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{546--550}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Pancreas}},
  title        = {{Comparative study of antibacterial activity of pancreatic juice in six mammalian species}},
  url          = {{http://dx.doi.org/10.1097/00006676-199309000-00003}},
  doi          = {{10.1097/00006676-199309000-00003}},
  volume       = {{8}},
  year         = {{1993}},
}