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Risk-adapted Prostate Cancer Screening Achieves Mammography-like Benefits : Evidence and Implications for Europe

Carlsson, Sigrid V. LU ; Krilaviciute, Agne ; Al-Monajjed, Rouvier ; Seibold, Petra ; Kuczyk, Markus ; Gschwend, Jürgen E. ; Debus, Jürgen ; Antoch, Gerald ; Schimmöller, Lars and Schlemmer, Heinz Peter , et al. (2026) In European Urology 89(3). p.193-195
Abstract

Take Home Message Using Germany as a case example, a comparison between organized mammography screening and contemporary, risk-adapted screening for prostate cancer suggests that prostate-specific antigen–based early detection with incorporation of magnetic resonance imaging and active surveillance can achieve benefits comparable to those of mammography while addressing previous concerns about overdiagnosis and overtreatment. Findings from the PROBASE trial support the potential of such an approach to provide a favorable balance between benefit and harm when initiated at younger ages.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Urology
volume
89
issue
3
pages
3 pages
publisher
Elsevier
external identifiers
  • scopus:105025112470
  • pmid:41419391
ISSN
0302-2838
DOI
10.1016/j.eururo.2025.12.002
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2025 European Association of Urology.
id
2e07b157-650d-4c5b-be3f-fdede8aa3938
date added to LUP
2026-03-02 13:48:05
date last changed
2026-06-09 03:17:56
@misc{2e07b157-650d-4c5b-be3f-fdede8aa3938,
  abstract     = {{<p>Take Home Message Using Germany as a case example, a comparison between organized mammography screening and contemporary, risk-adapted screening for prostate cancer suggests that prostate-specific antigen–based early detection with incorporation of magnetic resonance imaging and active surveillance can achieve benefits comparable to those of mammography while addressing previous concerns about overdiagnosis and overtreatment. Findings from the PROBASE trial support the potential of such an approach to provide a favorable balance between benefit and harm when initiated at younger ages.</p>}},
  author       = {{Carlsson, Sigrid V. and Krilaviciute, Agne and Al-Monajjed, Rouvier and Seibold, Petra and Kuczyk, Markus and Gschwend, Jürgen E. and Debus, Jürgen and Antoch, Gerald and Schimmöller, Lars and Schlemmer, Heinz Peter and Kristiansen, Glen and Kaaks, Rudolf and Becker, Nikolaus and Albers, Peter}},
  issn         = {{0302-2838}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{193--195}},
  publisher    = {{Elsevier}},
  series       = {{European Urology}},
  title        = {{Risk-adapted Prostate Cancer Screening Achieves Mammography-like Benefits : Evidence and Implications for Europe}},
  url          = {{http://dx.doi.org/10.1016/j.eururo.2025.12.002}},
  doi          = {{10.1016/j.eururo.2025.12.002}},
  volume       = {{89}},
  year         = {{2026}},
}