Advanced

Electrocochleographic signal analysis : condensation and rarefaction click stimulation contributes to diagnosis in Menière's disorder

Sass, K LU ; Densert, Barbara; Magnusson, M LU and Whitaker, S. (1998) In Audiology 37(4). p.198-206
Abstract

Thirty patients with Menière's disorder, 11 patients with cochlear hearing loss of other aetiologies and 10 normally-hearing subjects, were investigated using transtympanic electrocochleography (TT ECochG). Alternating polarity clicks, condensation and rarefaction clicks and long tone-bursts of 1 kHz were used for stimulation. The latencies of the AP responses to click stimulation were evaluated. It was found that the latency differences between the condensation and rarefaction click-evoked responses were significantly larger in patients with Menière's disorder as compared to normal subjects and to patients with other cochlear hearing losses. It was found that the sensitivity of TT ECochG, obtained by using measurements of SP-AP ratios... (More)

Thirty patients with Menière's disorder, 11 patients with cochlear hearing loss of other aetiologies and 10 normally-hearing subjects, were investigated using transtympanic electrocochleography (TT ECochG). Alternating polarity clicks, condensation and rarefaction clicks and long tone-bursts of 1 kHz were used for stimulation. The latencies of the AP responses to click stimulation were evaluated. It was found that the latency differences between the condensation and rarefaction click-evoked responses were significantly larger in patients with Menière's disorder as compared to normal subjects and to patients with other cochlear hearing losses. It was found that the sensitivity of TT ECochG, obtained by using measurements of SP-AP ratios and the SP amplitude at 1 kHz burst stimulation, increased from 83 per cent to 87 per cent by addition of the con-rar shift measurement. The specificity of TT ECochG obtained by this combination of variables was 100 per cent in our material. The results of the study indicate that the latency shift found in responses evoked by clicks of opposite polarities in TT ECochG, can be a useful parameter in the detection of suspected endolymphatic hydrops.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Acoustic Stimulation, Adult, Audiometry, Evoked Response, Audiometry, Pure-Tone, Cochlea, Female, Hearing Loss, Sensorineural, Humans, Male, Meniere Disease, Middle Aged, Comparative Study, Journal Article
in
Audiology
volume
37
issue
4
pages
9 pages
publisher
Karger
external identifiers
  • scopus:0031694589
ISSN
0020-6091
language
English
LU publication?
yes
id
2e44b6b2-5764-4287-8887-b3c9a15e2e45
date added to LUP
2017-05-03 12:23:15
date last changed
2017-05-08 10:08:22
@article{2e44b6b2-5764-4287-8887-b3c9a15e2e45,
  abstract     = {<p>Thirty patients with Menière's disorder, 11 patients with cochlear hearing loss of other aetiologies and 10 normally-hearing subjects, were investigated using transtympanic electrocochleography (TT ECochG). Alternating polarity clicks, condensation and rarefaction clicks and long tone-bursts of 1 kHz were used for stimulation. The latencies of the AP responses to click stimulation were evaluated. It was found that the latency differences between the condensation and rarefaction click-evoked responses were significantly larger in patients with Menière's disorder as compared to normal subjects and to patients with other cochlear hearing losses. It was found that the sensitivity of TT ECochG, obtained by using measurements of SP-AP ratios and the SP amplitude at 1 kHz burst stimulation, increased from 83 per cent to 87 per cent by addition of the con-rar shift measurement. The specificity of TT ECochG obtained by this combination of variables was 100 per cent in our material. The results of the study indicate that the latency shift found in responses evoked by clicks of opposite polarities in TT ECochG, can be a useful parameter in the detection of suspected endolymphatic hydrops.</p>},
  author       = {Sass, K and Densert, Barbara and Magnusson, M and Whitaker, S.},
  issn         = {0020-6091},
  keyword      = {Acoustic Stimulation,Adult,Audiometry, Evoked Response,Audiometry, Pure-Tone,Cochlea,Female,Hearing Loss, Sensorineural,Humans,Male,Meniere Disease,Middle Aged,Comparative Study,Journal Article},
  language     = {eng},
  month        = {09},
  number       = {4},
  pages        = {198--206},
  publisher    = {Karger},
  series       = {Audiology},
  title        = {Electrocochleographic signal analysis : condensation and rarefaction click stimulation contributes to diagnosis in Menière's disorder},
  volume       = {37},
  year         = {1998},
}