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Subthalamic deep brain stimulation improves smooth pursuit and saccade performance in patients with Parkinson's disease.

Nilsson, Maria H LU ; Patel, Mitesh LU ; Rehncrona, Stig LU ; Magnusson, Måns LU and Fransson, Per-Anders LU (2013) In Journal of NeuroEngineering and Rehabilitation 10(April,3).
Abstract
Deep brain stimulation (DBS) in the subthalamic nucleus (STN) significantly reduces symptoms of Parkinson's disease (PD) such as bradykinesia, tremor and rigidity. It also reduces the need for anti-PD medication, and thereby potential side-effects of L-Dopa. Although DBS in the STN is a highly effective therapeutic intervention in PD, its mechanism and effects on oculomotor eye movement control and particularly smooth pursuit eye movements have to date rarely been investigated. Furthermore, previous reports provide conflicting information. The aim was to investigate how DBS in STN affected oculomotor performance in persons with PD using novel analysis techniques.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of NeuroEngineering and Rehabilitation
volume
10
issue
April,3
publisher
BioMed Central
external identifiers
  • wos:000317228300001
  • pmid:23551890
  • scopus:84875636184
ISSN
1743-0003
DOI
10.1186/1743-0003-10-33
language
English
LU publication?
yes
id
2f4164f2-32c8-4e98-97d0-807463d88065 (old id 3734253)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23551890?dopt=Abstract
date added to LUP
2013-05-02 10:27:21
date last changed
2019-01-20 04:19:27
@article{2f4164f2-32c8-4e98-97d0-807463d88065,
  abstract     = {Deep brain stimulation (DBS) in the subthalamic nucleus (STN) significantly reduces symptoms of Parkinson's disease (PD) such as bradykinesia, tremor and rigidity. It also reduces the need for anti-PD medication, and thereby potential side-effects of L-Dopa. Although DBS in the STN is a highly effective therapeutic intervention in PD, its mechanism and effects on oculomotor eye movement control and particularly smooth pursuit eye movements have to date rarely been investigated. Furthermore, previous reports provide conflicting information. The aim was to investigate how DBS in STN affected oculomotor performance in persons with PD using novel analysis techniques.},
  articleno    = {33},
  author       = {Nilsson, Maria H and Patel, Mitesh and Rehncrona, Stig and Magnusson, Måns and Fransson, Per-Anders},
  issn         = {1743-0003},
  language     = {eng},
  number       = {April,3},
  publisher    = {BioMed Central},
  series       = {Journal of NeuroEngineering and Rehabilitation},
  title        = {Subthalamic deep brain stimulation improves smooth pursuit and saccade performance in patients with Parkinson's disease.},
  url          = {http://dx.doi.org/10.1186/1743-0003-10-33},
  volume       = {10},
  year         = {2013},
}