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Molecular analysis of Philadelphia-positive childhood chronic myeloid leukemia.

Fioretos, Thoas LU ; Heim, Sverre LU ; Garwicz, Stanislaw LU ; Ludvigsson, J and Mitelman, Felix LU (1992) In Leukemia 6(7). p.723-725
Abstract
The breakpoints in chromosome 22 were determined in five children with Philadelphia-positive chronic myeloid leukemia. All had rearrangements within the major breakpoint cluster region (M-bcr). Four patients had breakpoints in the 5' region of M-bcr (zones 1-3), whereas one had a rearrangement in the 3' region (zone 4). The patient with the 3' rearrangement was the only one to develop a lymphoid blast crisis; he also had a substantially longer survival (102 months) than the others (11-54 months).
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Leukemia
volume
6
issue
7
pages
723 - 725
publisher
Nature Publishing Group
external identifiers
  • scopus:0026755447
ISSN
1476-5551
language
English
LU publication?
yes
id
82f19ac1-e6c7-43f4-a048-7fbd866b7574 (old id 30092)
date added to LUP
2007-06-11 08:33:26
date last changed
2017-01-01 07:09:57
@article{82f19ac1-e6c7-43f4-a048-7fbd866b7574,
  abstract     = {The breakpoints in chromosome 22 were determined in five children with Philadelphia-positive chronic myeloid leukemia. All had rearrangements within the major breakpoint cluster region (M-bcr). Four patients had breakpoints in the 5' region of M-bcr (zones 1-3), whereas one had a rearrangement in the 3' region (zone 4). The patient with the 3' rearrangement was the only one to develop a lymphoid blast crisis; he also had a substantially longer survival (102 months) than the others (11-54 months).},
  author       = {Fioretos, Thoas and Heim, Sverre and Garwicz, Stanislaw and Ludvigsson, J and Mitelman, Felix},
  issn         = {1476-5551},
  language     = {eng},
  number       = {7},
  pages        = {723--725},
  publisher    = {Nature Publishing Group},
  series       = {Leukemia},
  title        = {Molecular analysis of Philadelphia-positive childhood chronic myeloid leukemia.},
  volume       = {6},
  year         = {1992},
}