Single-fiber diffuse optical time-of-flight spectroscopy
(2012) In Optics Letters 37(14). p.2877-2879- Abstract
- We demonstrate interstitial diffuse optical time-of-fight spectroscopy based on a single fiber for both light delivery and detection. Detector saturation due to the massive short-time reflection is avoided by ultrafast gating of a single photon avalanche diode. We show that the effects of scattering and absorption are separable and that absorption can be assessed independently of scattering. Measurements on calibrated liquid phantoms and subsequent Monte Carlo-based evaluation illustrate that absorption coefficients can be accurately assessed over a wide range of medically relevant optical properties. Our findings pave the way to simplified and less invasive interstitial in vivo spectroscopy. (C) 2012 Optical Society of America
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3059858
- author
- Alerstam, Erik LU ; Svensson, Tomas LU ; Andersson-Engels, Stefan LU ; Spinelli, Lorenzo ; Contini, Davide ; Dalla Mora, Alberto ; Tosi, Alberto ; Zappa, Franco and Pifferi, Antonio
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Optics Letters
- volume
- 37
- issue
- 14
- pages
- 2877 - 2879
- publisher
- Optical Society of America
- external identifiers
-
- wos:000306709900036
- scopus:84864339037
- ISSN
- 0146-9592
- DOI
- 10.1364/OL.37.002877
- language
- English
- LU publication?
- yes
- id
- 83e6f46a-bafc-4add-a8a1-4af3e18f4e02 (old id 3059858)
- date added to LUP
- 2016-04-01 13:54:31
- date last changed
- 2022-02-26 23:48:31
@article{83e6f46a-bafc-4add-a8a1-4af3e18f4e02, abstract = {{We demonstrate interstitial diffuse optical time-of-fight spectroscopy based on a single fiber for both light delivery and detection. Detector saturation due to the massive short-time reflection is avoided by ultrafast gating of a single photon avalanche diode. We show that the effects of scattering and absorption are separable and that absorption can be assessed independently of scattering. Measurements on calibrated liquid phantoms and subsequent Monte Carlo-based evaluation illustrate that absorption coefficients can be accurately assessed over a wide range of medically relevant optical properties. Our findings pave the way to simplified and less invasive interstitial in vivo spectroscopy. (C) 2012 Optical Society of America}}, author = {{Alerstam, Erik and Svensson, Tomas and Andersson-Engels, Stefan and Spinelli, Lorenzo and Contini, Davide and Dalla Mora, Alberto and Tosi, Alberto and Zappa, Franco and Pifferi, Antonio}}, issn = {{0146-9592}}, language = {{eng}}, number = {{14}}, pages = {{2877--2879}}, publisher = {{Optical Society of America}}, series = {{Optics Letters}}, title = {{Single-fiber diffuse optical time-of-flight spectroscopy}}, url = {{https://lup.lub.lu.se/search/files/3660483/3131302.pdf}}, doi = {{10.1364/OL.37.002877}}, volume = {{37}}, year = {{2012}}, }