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Chromosomal abnormalities in inflammatory pseudotumor of the urinary bladder

Fadl-Elmula, I ; Gorunova, Ludmila LU ; Mandahl, Nils LU and Heim, S (2003) In Cancer Genetics and Cytogenetics 143(2). p.169-171
Abstract
Inflammatory pseudotumors of the urinary bladder are rare, benign, nonepithelial tumors. Fewer than 30 have been reported, and no data are available on their karyotypic characteristics and/or the molecular mechanisms of pathogenesis. We performed short-term culturing and cytogenetic analysis of an inflammatory pseudotumor of the bladder, finding a der(20)t(12;20)(q13similar toq15;q13) as the only cytogenetic aberration. The detection of a 12q13similar toq15 rearrangement in the inflammatory pseudotumor indicates that this lesion is pathogenetically related to other benign mesenchymal tumors displaying, for example, lipogenic or leiomyomatous differentiation, something that is in sharp contrast to the karyotypic profile of epithelial tumors... (More)
Inflammatory pseudotumors of the urinary bladder are rare, benign, nonepithelial tumors. Fewer than 30 have been reported, and no data are available on their karyotypic characteristics and/or the molecular mechanisms of pathogenesis. We performed short-term culturing and cytogenetic analysis of an inflammatory pseudotumor of the bladder, finding a der(20)t(12;20)(q13similar toq15;q13) as the only cytogenetic aberration. The detection of a 12q13similar toq15 rearrangement in the inflammatory pseudotumor indicates that this lesion is pathogenetically related to other benign mesenchymal tumors displaying, for example, lipogenic or leiomyomatous differentiation, something that is in sharp contrast to the karyotypic profile of epithelial tumors of the urinary bladder mucosa. (C) 2003 Elsevier Inc. All rights reserved. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cancer Genetics and Cytogenetics
volume
143
issue
2
pages
169 - 171
publisher
Elsevier
external identifiers
  • wos:000183263300011
  • pmid:12781452
  • scopus:0037716662
ISSN
0165-4608
DOI
10.1016/S0165-4608(02)00846-4
language
English
LU publication?
yes
id
8b75399f-0fd1-4f33-a30f-30bae6f25dcf (old id 309649)
date added to LUP
2016-04-01 16:41:36
date last changed
2022-01-28 21:28:34
@article{8b75399f-0fd1-4f33-a30f-30bae6f25dcf,
  abstract     = {{Inflammatory pseudotumors of the urinary bladder are rare, benign, nonepithelial tumors. Fewer than 30 have been reported, and no data are available on their karyotypic characteristics and/or the molecular mechanisms of pathogenesis. We performed short-term culturing and cytogenetic analysis of an inflammatory pseudotumor of the bladder, finding a der(20)t(12;20)(q13similar toq15;q13) as the only cytogenetic aberration. The detection of a 12q13similar toq15 rearrangement in the inflammatory pseudotumor indicates that this lesion is pathogenetically related to other benign mesenchymal tumors displaying, for example, lipogenic or leiomyomatous differentiation, something that is in sharp contrast to the karyotypic profile of epithelial tumors of the urinary bladder mucosa. (C) 2003 Elsevier Inc. All rights reserved.}},
  author       = {{Fadl-Elmula, I and Gorunova, Ludmila and Mandahl, Nils and Heim, S}},
  issn         = {{0165-4608}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{169--171}},
  publisher    = {{Elsevier}},
  series       = {{Cancer Genetics and Cytogenetics}},
  title        = {{Chromosomal abnormalities in inflammatory pseudotumor of the urinary bladder}},
  url          = {{http://dx.doi.org/10.1016/S0165-4608(02)00846-4}},
  doi          = {{10.1016/S0165-4608(02)00846-4}},
  volume       = {{143}},
  year         = {{2003}},
}