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Chromosomal abnormalities in inflammatory pseudotumor of the urinary bladder

Fadl-Elmula, I; Gorunova, Ludmila LU ; Mandahl, Nils LU and Heim, S (2003) In Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00 143(2). p.169-171
Abstract
Inflammatory pseudotumors of the urinary bladder are rare, benign, nonepithelial tumors. Fewer than 30 have been reported, and no data are available on their karyotypic characteristics and/or the molecular mechanisms of pathogenesis. We performed short-term culturing and cytogenetic analysis of an inflammatory pseudotumor of the bladder, finding a der(20)t(12;20)(q13similar toq15;q13) as the only cytogenetic aberration. The detection of a 12q13similar toq15 rearrangement in the inflammatory pseudotumor indicates that this lesion is pathogenetically related to other benign mesenchymal tumors displaying, for example, lipogenic or leiomyomatous differentiation, something that is in sharp contrast to the karyotypic profile of epithelial tumors... (More)
Inflammatory pseudotumors of the urinary bladder are rare, benign, nonepithelial tumors. Fewer than 30 have been reported, and no data are available on their karyotypic characteristics and/or the molecular mechanisms of pathogenesis. We performed short-term culturing and cytogenetic analysis of an inflammatory pseudotumor of the bladder, finding a der(20)t(12;20)(q13similar toq15;q13) as the only cytogenetic aberration. The detection of a 12q13similar toq15 rearrangement in the inflammatory pseudotumor indicates that this lesion is pathogenetically related to other benign mesenchymal tumors displaying, for example, lipogenic or leiomyomatous differentiation, something that is in sharp contrast to the karyotypic profile of epithelial tumors of the urinary bladder mucosa. (C) 2003 Elsevier Inc. All rights reserved. (Less)
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published
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in
Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00
volume
143
issue
2
pages
169 - 171
publisher
Elsevier
external identifiers
  • wos:000183263300011
  • pmid:12781452
  • scopus:0037716662
ISSN
0165-4608
DOI
language
English
LU publication?
yes
id
8b75399f-0fd1-4f33-a30f-30bae6f25dcf (old id 309649)
date added to LUP
2007-09-03 07:19:56
date last changed
2018-05-29 12:32:22
@article{8b75399f-0fd1-4f33-a30f-30bae6f25dcf,
  abstract     = {Inflammatory pseudotumors of the urinary bladder are rare, benign, nonepithelial tumors. Fewer than 30 have been reported, and no data are available on their karyotypic characteristics and/or the molecular mechanisms of pathogenesis. We performed short-term culturing and cytogenetic analysis of an inflammatory pseudotumor of the bladder, finding a der(20)t(12;20)(q13similar toq15;q13) as the only cytogenetic aberration. The detection of a 12q13similar toq15 rearrangement in the inflammatory pseudotumor indicates that this lesion is pathogenetically related to other benign mesenchymal tumors displaying, for example, lipogenic or leiomyomatous differentiation, something that is in sharp contrast to the karyotypic profile of epithelial tumors of the urinary bladder mucosa. (C) 2003 Elsevier Inc. All rights reserved.},
  author       = {Fadl-Elmula, I and Gorunova, Ludmila and Mandahl, Nils and Heim, S},
  issn         = {0165-4608},
  language     = {eng},
  number       = {2},
  pages        = {169--171},
  publisher    = {Elsevier},
  series       = {Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00},
  title        = {Chromosomal abnormalities in inflammatory pseudotumor of the urinary bladder},
  url          = {http://dx.doi.org/},
  volume       = {143},
  year         = {2003},
}