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Reproductive choices of haemophilia carriers

Tedgård, U. LU ; Ljung, R. LU and McNeil, T. F. LU (1999) In British Journal of Haematology 106(2). p.421-426
Abstract

The actual reproductive choices made by slightly over a quarter of all the carriers of severe or moderate haemophilia in Sweden were investigated and compared with those of a randomly selected age-matched group of women who were not carriers of haemophilia. In general, the 105 carriers had the same number of children as other women of similar age. However, carriers who did not choose prenatal diagnosis (PD) often abstained from further pregnancies after the birth of a haemophilic child, and they had significantly fewer children than the remainder of the carriers, as well as fewer children than women in the control group. Logistic regression analysis showed choice of PD to be correlated to a positive attitude towards abortion following... (More)

The actual reproductive choices made by slightly over a quarter of all the carriers of severe or moderate haemophilia in Sweden were investigated and compared with those of a randomly selected age-matched group of women who were not carriers of haemophilia. In general, the 105 carriers had the same number of children as other women of similar age. However, carriers who did not choose prenatal diagnosis (PD) often abstained from further pregnancies after the birth of a haemophilic child, and they had significantly fewer children than the remainder of the carriers, as well as fewer children than women in the control group. Logistic regression analysis showed choice of PD to be correlated to a positive attitude towards abortion following PD and a family history of haemophilia. Carriers who have experienced the complications of haemophilia or its treatment appear to be more in favor of PD than women whose haemophilic children have received modern treatment without complications.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Birth rate, Haemophilia, Prenatal diagnosis, Reproduction, Therapeutic abortion
in
British Journal of Haematology
volume
106
issue
2
pages
421 - 426
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • Scopus:0032870816
ISSN
0007-1048
DOI
10.1046/j.1365-2141.1999.01566.x
language
English
LU publication?
yes
id
30fc6602-bd2b-48b0-b0ab-4ca1752d2cd2
date added to LUP
2016-11-25 14:41:40
date last changed
2017-02-26 04:43:10
@article{30fc6602-bd2b-48b0-b0ab-4ca1752d2cd2,
  abstract     = {<p>The actual reproductive choices made by slightly over a quarter of all the carriers of severe or moderate haemophilia in Sweden were investigated and compared with those of a randomly selected age-matched group of women who were not carriers of haemophilia. In general, the 105 carriers had the same number of children as other women of similar age. However, carriers who did not choose prenatal diagnosis (PD) often abstained from further pregnancies after the birth of a haemophilic child, and they had significantly fewer children than the remainder of the carriers, as well as fewer children than women in the control group. Logistic regression analysis showed choice of PD to be correlated to a positive attitude towards abortion following PD and a family history of haemophilia. Carriers who have experienced the complications of haemophilia or its treatment appear to be more in favor of PD than women whose haemophilic children have received modern treatment without complications.</p>},
  author       = {Tedgård, U. and Ljung, R. and McNeil, T. F.},
  issn         = {0007-1048},
  keyword      = {Birth rate,Haemophilia,Prenatal diagnosis,Reproduction,Therapeutic abortion},
  language     = {eng},
  number       = {2},
  pages        = {421--426},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {British Journal of Haematology},
  title        = {Reproductive choices of haemophilia carriers},
  url          = {http://dx.doi.org/10.1046/j.1365-2141.1999.01566.x},
  volume       = {106},
  year         = {1999},
}