Successful treatment of fulminant hepatitis B and fulminant hepatitis B and D coinfection explained by inhibitory effect on the immune response?
(1991) In Progress in Clinical and Biological Research 364. p.421-427- Abstract
Foscarnet has been shown to inhibit the proliferation of human T and B lymphocytes in vitro. The production of lymphokines was more strongly affected than the DNA synthesis. Monocyte function was only partly inhibited by the highest foscarnet concentration tried. The influence of foscarnet on the immune system could explain the beneficial effect observed in patients with HBV-related fulminant hepatitis treated with foscarnet.
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https://lup.lub.lu.se/record/311f2e2c-8781-4d8d-a483-4327b6cfd416
- author
- Hansson, B. G. LU ; Riesbeck, K. LU ; Nordenfelt, E. and Weiland, O.
- organization
- publishing date
- 1991-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Progress in Clinical and Biological Research
- volume
- 364
- pages
- 421 - 427
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:0025983029
- pmid:1826956
- ISSN
- 0361-7742
- language
- English
- LU publication?
- yes
- id
- 311f2e2c-8781-4d8d-a483-4327b6cfd416
- date added to LUP
- 2019-03-27 14:27:47
- date last changed
- 2024-01-01 00:27:27
@article{311f2e2c-8781-4d8d-a483-4327b6cfd416, abstract = {{<p>Foscarnet has been shown to inhibit the proliferation of human T and B lymphocytes in vitro. The production of lymphokines was more strongly affected than the DNA synthesis. Monocyte function was only partly inhibited by the highest foscarnet concentration tried. The influence of foscarnet on the immune system could explain the beneficial effect observed in patients with HBV-related fulminant hepatitis treated with foscarnet.</p>}}, author = {{Hansson, B. G. and Riesbeck, K. and Nordenfelt, E. and Weiland, O.}}, issn = {{0361-7742}}, language = {{eng}}, month = {{01}}, pages = {{421--427}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Progress in Clinical and Biological Research}}, title = {{Successful treatment of fulminant hepatitis B and fulminant hepatitis B and D coinfection explained by inhibitory effect on the immune response?}}, volume = {{364}}, year = {{1991}}, }