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Clinical outcome of erythema migrans after treatment with phenoxymethyl penicillin

Bennet, Louise LU ; Danell, S and Berglund, Johan LU (2003) In Scandinavian Journal of Infectious Diseases 35(2). p.129-131
Abstract
In a 5 y retrospective follow-up study in southern Sweden of 708 adult individuals with erythema migrans as the single manifestation of Lyme borreliosis, the clinical outcome and the antibiotic treatment were studied. 80%, were treated with phenoxymethyl penicillin, 15% with doxycycline and 5% with other antibiotics. Phenoxymethyl penicillin and doxycycline were extremely effective: 98 and 94% of the individuals reported complete recovery without complications. Few individuals reported the development of new symptoms following treatment and none developed any late manifestation of Lyme borreliosis during the observation period. Thus, in the area studied the treatment of the early localized manifestation of Lyme borreliosis (erythema... (More)
In a 5 y retrospective follow-up study in southern Sweden of 708 adult individuals with erythema migrans as the single manifestation of Lyme borreliosis, the clinical outcome and the antibiotic treatment were studied. 80%, were treated with phenoxymethyl penicillin, 15% with doxycycline and 5% with other antibiotics. Phenoxymethyl penicillin and doxycycline were extremely effective: 98 and 94% of the individuals reported complete recovery without complications. Few individuals reported the development of new symptoms following treatment and none developed any late manifestation of Lyme borreliosis during the observation period. Thus, in the area studied the treatment of the early localized manifestation of Lyme borreliosis (erythema migrans) with antibiotics was extremely successful. The current Swedish recommendation to use phenoxymethyl penicillin, when no sign of disseminated infection or coinfection with other tick-borne pathogens is present, seems excellent. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scandinavian Journal of Infectious Diseases
volume
35
issue
2
pages
129 - 131
publisher
Informa Healthcare
external identifiers
  • wos:000182079500011
  • scopus:0037244223
ISSN
1651-1980
DOI
10.1080/0036554021000027009
language
English
LU publication?
yes
id
74051047-213b-473f-9b86-9319ea6081f0 (old id 313911)
date added to LUP
2007-08-23 07:56:55
date last changed
2018-01-07 09:27:25
@misc{74051047-213b-473f-9b86-9319ea6081f0,
  abstract     = {In a 5 y retrospective follow-up study in southern Sweden of 708 adult individuals with erythema migrans as the single manifestation of Lyme borreliosis, the clinical outcome and the antibiotic treatment were studied. 80%, were treated with phenoxymethyl penicillin, 15% with doxycycline and 5% with other antibiotics. Phenoxymethyl penicillin and doxycycline were extremely effective: 98 and 94% of the individuals reported complete recovery without complications. Few individuals reported the development of new symptoms following treatment and none developed any late manifestation of Lyme borreliosis during the observation period. Thus, in the area studied the treatment of the early localized manifestation of Lyme borreliosis (erythema migrans) with antibiotics was extremely successful. The current Swedish recommendation to use phenoxymethyl penicillin, when no sign of disseminated infection or coinfection with other tick-borne pathogens is present, seems excellent.},
  author       = {Bennet, Louise and Danell, S and Berglund, Johan},
  issn         = {1651-1980},
  language     = {eng},
  number       = {2},
  pages        = {129--131},
  publisher    = {Informa Healthcare},
  series       = {Scandinavian Journal of Infectious Diseases},
  title        = {Clinical outcome of erythema migrans after treatment with phenoxymethyl penicillin},
  url          = {http://dx.doi.org/10.1080/0036554021000027009},
  volume       = {35},
  year         = {2003},
}