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European prospective investigation into cancer and nutrition (EPIC): study populations and data collection

Riboli, E; Hunt, KJ; Slimani, N; Ferrari, P; Norat, T; Fahey, M; Charrondiere, UR; Hemon, B; Casagrande, C and Vignat, J, et al. (2002) In Public Health Nutrition 5(6B). p.1113-1124
Abstract
The European Prospective Investigation into Cancer and. Nutrition (EPIC) is an ongoing multi-centre prospective cohort study designed to investigate the relationship between nutrition and cancer, with the potential for studying other diseases as well. The study currently includes 519 978 participants (366 521 women and 153457 men, mostly aged 35-70 years) in 23 centres located in 10 European countries, to be followed for cancer incidence and cause-specific mortality for several decades. At enrolment, which took place between 1992 and 2000 at each of the different centres, information was collected through a non-dietary questionnaire on lifestyle variables and through a dietary questionnaire addressing usual diet. Anthropometric... (More)
The European Prospective Investigation into Cancer and. Nutrition (EPIC) is an ongoing multi-centre prospective cohort study designed to investigate the relationship between nutrition and cancer, with the potential for studying other diseases as well. The study currently includes 519 978 participants (366 521 women and 153457 men, mostly aged 35-70 years) in 23 centres located in 10 European countries, to be followed for cancer incidence and cause-specific mortality for several decades. At enrolment, which took place between 1992 and 2000 at each of the different centres, information was collected through a non-dietary questionnaire on lifestyle variables and through a dietary questionnaire addressing usual diet. Anthropometric measurements were performed and blood samples taken, from which plasma, serum, red cells and buffy coat fractions were separated and aliquoted for long-term storage, mostly in liquid nitrogen. To calibrate dietary measurements, a standardised, computer-assisted 24-hour dietary recall was implemented at each centre on stratified random samples of the participants, for a total of 36 900 subjects. EPIC represents the largest single resource available today world-wide for prospective investigations on the aetiology of cancers (and other diseases) that can integrate questionnaire data on lifestyle and diet, biomarkers of diet and of endogenous metabolism (e.g. hormones and growth factors) and genetic polymorphisms. First results of case-control studies nested within the cohort are expected early in 2003. The present paper provides a description of the EPIC study, with the aim of simplifying reference to it in future papers reporting substantive or methodological studies carried out in the EPIC cohort. (Less)
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organization
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Contribution to journal
publication status
published
subject
keywords
EPIC study, biological samples, anthropometry, cohort study, chronic diseases, nutrition, cancer, Europe
in
Public Health Nutrition
volume
5
issue
6B
pages
1113 - 1124
publisher
Cambridge University Press
external identifiers
  • pmid:12639222
  • wos:000181402400002
  • scopus:0345700787
ISSN
1475-2727
DOI
10.1079/PHN2002394
language
English
LU publication?
yes
id
80622d0c-1c5b-424f-b2c0-6255d3b22f6c (old id 316426)
date added to LUP
2007-11-09 08:34:49
date last changed
2017-12-10 04:24:51
@article{80622d0c-1c5b-424f-b2c0-6255d3b22f6c,
  abstract     = {The European Prospective Investigation into Cancer and. Nutrition (EPIC) is an ongoing multi-centre prospective cohort study designed to investigate the relationship between nutrition and cancer, with the potential for studying other diseases as well. The study currently includes 519 978 participants (366 521 women and 153457 men, mostly aged 35-70 years) in 23 centres located in 10 European countries, to be followed for cancer incidence and cause-specific mortality for several decades. At enrolment, which took place between 1992 and 2000 at each of the different centres, information was collected through a non-dietary questionnaire on lifestyle variables and through a dietary questionnaire addressing usual diet. Anthropometric measurements were performed and blood samples taken, from which plasma, serum, red cells and buffy coat fractions were separated and aliquoted for long-term storage, mostly in liquid nitrogen. To calibrate dietary measurements, a standardised, computer-assisted 24-hour dietary recall was implemented at each centre on stratified random samples of the participants, for a total of 36 900 subjects. EPIC represents the largest single resource available today world-wide for prospective investigations on the aetiology of cancers (and other diseases) that can integrate questionnaire data on lifestyle and diet, biomarkers of diet and of endogenous metabolism (e.g. hormones and growth factors) and genetic polymorphisms. First results of case-control studies nested within the cohort are expected early in 2003. The present paper provides a description of the EPIC study, with the aim of simplifying reference to it in future papers reporting substantive or methodological studies carried out in the EPIC cohort.},
  author       = {Riboli, E and Hunt, KJ and Slimani, N and Ferrari, P and Norat, T and Fahey, M and Charrondiere, UR and Hemon, B and Casagrande, C and Vignat, J and Overvad, K and Tjonneland, A and Clavel-Chapelon, F and Thiebaut, A and Wahrendorf, J and Boeing, H and Trichopoulos, D and Trichopoulou, A and Vineis, P and Palli, D and Bueno-de-Mesquita, HB and Peeters, PHM and Lund, E and Engeset, D and Gonzalez, CA and Barricarte, A and Berglund, Göran and Hallmans, G and Day, NE and Key, TJ and Kaaks, R and Saracci, R},
  issn         = {1475-2727},
  keyword      = {EPIC study,biological samples,anthropometry,cohort study,chronic diseases,nutrition,cancer,Europe},
  language     = {eng},
  number       = {6B},
  pages        = {1113--1124},
  publisher    = {Cambridge University Press},
  series       = {Public Health Nutrition},
  title        = {European prospective investigation into cancer and nutrition (EPIC): study populations and data collection},
  url          = {http://dx.doi.org/10.1079/PHN2002394},
  volume       = {5},
  year         = {2002},
}