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Molecular genetic characterization of the 11q13 breakpoint in a desmoplastic fibroma of bone

Trombetta, Domenico; Macchia, Gemma; Mandahl, Nils LU ; Hansén Nord, Karolin LU and Mertens, Fredrik LU (2012) In Cancer genetics 205(7-8). p.410-413
Abstract
Desmoplastic fibroma (DFB) is a benign primary bone tumor that usually occurs in adolescents and young adults. The genetic information on DFB is very limited. We here present cytogenetic, fluorescence in situ hybridization and single nucleotide polymorphism array findings in a case that had a rearrangement involving chromosomes 11 and 19 at G-banding analysis. The results showed that the breakpoint in 11q was different from that in desmoplastic fibroblastomas, and a segment containing five genes was hemizygously deleted from 11q13.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Desmoplastic fibroma, desmoplastic fibroblastoma, FISH, SNP array, 11q13
in
Cancer genetics
volume
205
issue
7-8
pages
410 - 413
publisher
Elsevier
external identifiers
  • wos:000307685700008
  • scopus:84867162632
ISSN
2210-7762
DOI
10.1016/j.cancergen.2012.05.002
language
English
LU publication?
yes
id
aa517614-cb68-4c18-ad5d-dbc6816f955d (old id 3191551)
date added to LUP
2012-12-03 07:12:37
date last changed
2017-06-11 03:05:07
@article{aa517614-cb68-4c18-ad5d-dbc6816f955d,
  abstract     = {Desmoplastic fibroma (DFB) is a benign primary bone tumor that usually occurs in adolescents and young adults. The genetic information on DFB is very limited. We here present cytogenetic, fluorescence in situ hybridization and single nucleotide polymorphism array findings in a case that had a rearrangement involving chromosomes 11 and 19 at G-banding analysis. The results showed that the breakpoint in 11q was different from that in desmoplastic fibroblastomas, and a segment containing five genes was hemizygously deleted from 11q13.},
  author       = {Trombetta, Domenico and Macchia, Gemma and Mandahl, Nils and Hansén Nord, Karolin and Mertens, Fredrik},
  issn         = {2210-7762},
  keyword      = {Desmoplastic fibroma,desmoplastic fibroblastoma,FISH,SNP array,11q13},
  language     = {eng},
  number       = {7-8},
  pages        = {410--413},
  publisher    = {Elsevier},
  series       = {Cancer genetics},
  title        = {Molecular genetic characterization of the 11q13 breakpoint in a desmoplastic fibroma of bone},
  url          = {http://dx.doi.org/10.1016/j.cancergen.2012.05.002},
  volume       = {205},
  year         = {2012},
}