Molecular genetic characterization of the 11q13 breakpoint in a desmoplastic fibroma of bone
(2012) In Cancer Genetics 205(7-8). p.410-413- Abstract
- Desmoplastic fibroma (DFB) is a benign primary bone tumor that usually occurs in adolescents and young adults. The genetic information on DFB is very limited. We here present cytogenetic, fluorescence in situ hybridization and single nucleotide polymorphism array findings in a case that had a rearrangement involving chromosomes 11 and 19 at G-banding analysis. The results showed that the breakpoint in 11q was different from that in desmoplastic fibroblastomas, and a segment containing five genes was hemizygously deleted from 11q13.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3191551
- author
- Trombetta, Domenico ; Macchia, Gemma ; Mandahl, Nils LU ; Hansén Nord, Karolin LU and Mertens, Fredrik LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Desmoplastic fibroma, desmoplastic fibroblastoma, FISH, SNP array, 11q13
- in
- Cancer Genetics
- volume
- 205
- issue
- 7-8
- pages
- 410 - 413
- publisher
- Elsevier
- external identifiers
-
- wos:000307685700008
- scopus:84867162632
- pmid:22868002
- ISSN
- 2210-7762
- DOI
- 10.1016/j.cancergen.2012.05.002
- language
- English
- LU publication?
- yes
- id
- aa517614-cb68-4c18-ad5d-dbc6816f955d (old id 3191551)
- date added to LUP
- 2016-04-01 10:06:20
- date last changed
- 2022-01-25 19:45:49
@article{aa517614-cb68-4c18-ad5d-dbc6816f955d, abstract = {{Desmoplastic fibroma (DFB) is a benign primary bone tumor that usually occurs in adolescents and young adults. The genetic information on DFB is very limited. We here present cytogenetic, fluorescence in situ hybridization and single nucleotide polymorphism array findings in a case that had a rearrangement involving chromosomes 11 and 19 at G-banding analysis. The results showed that the breakpoint in 11q was different from that in desmoplastic fibroblastomas, and a segment containing five genes was hemizygously deleted from 11q13.}}, author = {{Trombetta, Domenico and Macchia, Gemma and Mandahl, Nils and Hansén Nord, Karolin and Mertens, Fredrik}}, issn = {{2210-7762}}, keywords = {{Desmoplastic fibroma; desmoplastic fibroblastoma; FISH; SNP array; 11q13}}, language = {{eng}}, number = {{7-8}}, pages = {{410--413}}, publisher = {{Elsevier}}, series = {{Cancer Genetics}}, title = {{Molecular genetic characterization of the 11q13 breakpoint in a desmoplastic fibroma of bone}}, url = {{http://dx.doi.org/10.1016/j.cancergen.2012.05.002}}, doi = {{10.1016/j.cancergen.2012.05.002}}, volume = {{205}}, year = {{2012}}, }