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Anthropometric measures in relation to risk of heart failure hospitalization: a Swedish population-based cohort study.

Borné, Yan LU ; Hedblad, Bo LU ; Essén, Birgitta LU and Engström, Gunnar LU (2014) In European Journal of Public Health 24(2). p.215-220
Abstract
BACKGROUND: It is unclear which anthropometric measure is most useful for assessment of the cardiovascular risk. We investigated the association between different anthropometric measures and risk of heart failure (HF) hospitalization. METHODS: BMI, waist-hip ratio (WHR), waist circumference (WC), body fat percentage (BF%), weight and height were measured among 26 653 subjects (aged 45-73 years) without history of myocardial infarction (MI), stroke or HF from the Malmö Diet and Cancer cohort at baseline in 1991-96. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years. RESULTS: Seven hundred and twenty-seven subjects were hospitalized with HF as primary diagnosis, of whom 157 had an MI before or concurrent with... (More)
BACKGROUND: It is unclear which anthropometric measure is most useful for assessment of the cardiovascular risk. We investigated the association between different anthropometric measures and risk of heart failure (HF) hospitalization. METHODS: BMI, waist-hip ratio (WHR), waist circumference (WC), body fat percentage (BF%), weight and height were measured among 26 653 subjects (aged 45-73 years) without history of myocardial infarction (MI), stroke or HF from the Malmö Diet and Cancer cohort at baseline in 1991-96. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years. RESULTS: Seven hundred and twenty-seven subjects were hospitalized with HF as primary diagnosis, of whom 157 had an MI before or concurrent with the HF. After adjustment for potential confounding factors, the hazard ratios of HF hospitalization (fourth vs. first sex-specific quartile) were 1.80 (95% CI: 1.45-2.24) for BMI, 1.87 (1.50-2.34) for WC, 1.77 (1.43-2.19) for WHR, 1.35 (1.09-1.68) for BF%, 1.93 (1.57-2.39) for weight and 1.18 (0.96-1.44) for height. Significant interactions between BMI and WC and WHR, respectively, were observed, and the joint exposure of high BMI and high WC or high WHR further increased the risk. The results were similar in secondary analyses, i.e. excluding incident HF with previous MI during the follow-up. CONCLUSION: Our results support the view that raised BMI, WC, WHR or BF% increases the risk of HF hospitalization. The joint exposure of high BMI and high WHR or high WC further increased the risk in an additive way. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Public Health
volume
24
issue
2
pages
215 - 220
publisher
Oxford University Press
external identifiers
  • pmid:23183497
  • wos:000334101000012
  • scopus:84897442703
ISSN
1101-1262
DOI
10.1093/eurpub/cks161
language
English
LU publication?
yes
id
f338f146-3149-4239-bf07-c42f633cd91a (old id 3218481)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23183497?dopt=Abstract
date added to LUP
2012-12-03 22:05:38
date last changed
2017-08-20 03:12:00
@article{f338f146-3149-4239-bf07-c42f633cd91a,
  abstract     = {BACKGROUND: It is unclear which anthropometric measure is most useful for assessment of the cardiovascular risk. We investigated the association between different anthropometric measures and risk of heart failure (HF) hospitalization. METHODS: BMI, waist-hip ratio (WHR), waist circumference (WC), body fat percentage (BF%), weight and height were measured among 26 653 subjects (aged 45-73 years) without history of myocardial infarction (MI), stroke or HF from the Malmö Diet and Cancer cohort at baseline in 1991-96. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years. RESULTS: Seven hundred and twenty-seven subjects were hospitalized with HF as primary diagnosis, of whom 157 had an MI before or concurrent with the HF. After adjustment for potential confounding factors, the hazard ratios of HF hospitalization (fourth vs. first sex-specific quartile) were 1.80 (95% CI: 1.45-2.24) for BMI, 1.87 (1.50-2.34) for WC, 1.77 (1.43-2.19) for WHR, 1.35 (1.09-1.68) for BF%, 1.93 (1.57-2.39) for weight and 1.18 (0.96-1.44) for height. Significant interactions between BMI and WC and WHR, respectively, were observed, and the joint exposure of high BMI and high WC or high WHR further increased the risk. The results were similar in secondary analyses, i.e. excluding incident HF with previous MI during the follow-up. CONCLUSION: Our results support the view that raised BMI, WC, WHR or BF% increases the risk of HF hospitalization. The joint exposure of high BMI and high WHR or high WC further increased the risk in an additive way.},
  author       = {Borné, Yan and Hedblad, Bo and Essén, Birgitta and Engström, Gunnar},
  issn         = {1101-1262},
  language     = {eng},
  number       = {2},
  pages        = {215--220},
  publisher    = {Oxford University Press},
  series       = {European Journal of Public Health},
  title        = {Anthropometric measures in relation to risk of heart failure hospitalization: a Swedish population-based cohort study.},
  url          = {http://dx.doi.org/10.1093/eurpub/cks161},
  volume       = {24},
  year         = {2014},
}