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Soluble Urokinase Plasminogen Activator Receptor is Associated With Inflammation in the Vulnerable Human Atherosclerotic Plaque.

Edsfeldt, Andreas LU ; Nitulescu, Mihaela LU ; Grufman, Helena LU ; Grönberg, Caitriona LU ; Persson, Ana LU ; Nilsson, Marie MN LU ; Persson, Margaretha LU ; Björkbacka, Harry LU and Goncalves, Isabel LU (2012) In Stroke; a journal of cerebral circulation 43(12). p.3305-3312
Abstract
Recently, plasma soluble urokinase plasminogen activator receptor (suPAR) has gained interest as a marker of cardiovascular risk. suPAR is released through the cleavage of urokinase plasminogen activator receptor (uPAR), which is found in monocytes, activated T-lymphocytes and endothelial cells, all involved in atherosclerosis. suPAR levels have been well studied in plasma, but no studies have focused on suPAR in human atherosclerotic plaques. The aim of this study was to determine whether suPAR measured in the plaque is associated with symptomatic plaques and plaque inflammation.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Stroke; a journal of cerebral circulation
volume
43
issue
12
pages
3305 - 3312
publisher
American Heart Association
external identifiers
  • WOS:000311497600035
  • PMID:23150653
  • Scopus:84870876982
ISSN
1524-4628
DOI
10.1161/STROKEAHA.112.664094
language
English
LU publication?
yes
id
aaf0c8d5-fb55-4e60-90da-78908533e062 (old id 3218966)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23150653?dopt=Abstract
date added to LUP
2012-12-03 15:00:03
date last changed
2017-02-12 04:23:55
@article{aaf0c8d5-fb55-4e60-90da-78908533e062,
  abstract     = {Recently, plasma soluble urokinase plasminogen activator receptor (suPAR) has gained interest as a marker of cardiovascular risk. suPAR is released through the cleavage of urokinase plasminogen activator receptor (uPAR), which is found in monocytes, activated T-lymphocytes and endothelial cells, all involved in atherosclerosis. suPAR levels have been well studied in plasma, but no studies have focused on suPAR in human atherosclerotic plaques. The aim of this study was to determine whether suPAR measured in the plaque is associated with symptomatic plaques and plaque inflammation.},
  author       = {Edsfeldt, Andreas and Nitulescu, Mihaela and Grufman, Helena and Grönberg, Caitriona and Persson, Ana and Nilsson, Marie MN and Persson, Margaretha and Björkbacka, Harry and Goncalves, Isabel},
  issn         = {1524-4628},
  language     = {eng},
  number       = {12},
  pages        = {3305--3312},
  publisher    = {American Heart Association},
  series       = {Stroke; a journal of cerebral circulation},
  title        = {Soluble Urokinase Plasminogen Activator Receptor is Associated With Inflammation in the Vulnerable Human Atherosclerotic Plaque.},
  url          = {http://dx.doi.org/10.1161/STROKEAHA.112.664094},
  volume       = {43},
  year         = {2012},
}