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The costs of exacerbations in chronic obstructive pulmonary disease (COPD)

Andersson, F; Borg, S; Jansson, SA; Jonsson, AC; Ericsson, A; Prütz, Christin LU ; Ronmark, E and Lundback, B (2002) In Respiratory Medicine 96(9). p.700-708
Abstract
Exacerbations are the key drivers in the costs of chronic obstructive pulmonary disease (COPD). The objective was to examine the costs of COPD exacerbations in relation to differing degrees of severity of exacerbations and of COPD. We identified 202 subjects with COPD, defined according to the BTS and ERS criteria. Exacerbations were divided into mild (self-managed), mild/moderate (telephone contact with a health-care centre and/or the use of anti biotics/systemic corticosteroids), moderate (health-care centre visits) and severe (emergency care visit or hospital admission). Exacerbations were identified by sending the subjects a letter inquiring whether they had any additional respiratory problems or influenza the previous winter. At least... (More)
Exacerbations are the key drivers in the costs of chronic obstructive pulmonary disease (COPD). The objective was to examine the costs of COPD exacerbations in relation to differing degrees of severity of exacerbations and of COPD. We identified 202 subjects with COPD, defined according to the BTS and ERS criteria. Exacerbations were divided into mild (self-managed), mild/moderate (telephone contact with a health-care centre and/or the use of anti biotics/systemic corticosteroids), moderate (health-care centre visits) and severe (emergency care visit or hospital admission). Exacerbations were identified by sending the subjects a letter inquiring whether they had any additional respiratory problems or influenza the previous winter. At least one exacerbation was reported by 61 subjects, who were then interviewed about resource use for these events. The average health-care costs per exacerbation were SEK 120(95% CI = 39-246), SEK 354 (252-475), SEK 2111 (1673-2612) and SEK 21852 (14436-29825) for mild, mild/moderate, moderate and severe exacerbations, respectively. Subjects with impaired lung function experienced more severe exacerbations, which was also reflected in the cost of exacerbations per severity of the disease during the 41 month study period (ranging from SEK 224 for mild to SEK 13708 for severe cases, median SEK 940). Exacerbations account for 35-45% of the total per capita health-care costs for COPD. In conclusion, costs varied considerably with the severity of the exacerbation as well as with the severity of COPD. The prevention of moderate-to-severe exacerbations could be very cost-effective and improve the quality of life. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
OLIN studies, frequency, severity, costs, COPD, exacerbations
in
Respiratory Medicine
volume
96
issue
9
pages
700 - 708
publisher
Elsevier
external identifiers
  • wos:000177862200008
  • pmid:12243316
  • scopus:0036739118
ISSN
1532-3064
DOI
10.1053/rmed.2002.1334
language
English
LU publication?
yes
id
9f23ec11-2dfb-441b-a624-2e20a6ac99a7 (old id 329359)
date added to LUP
2007-08-07 08:59:33
date last changed
2017-11-19 04:03:29
@article{9f23ec11-2dfb-441b-a624-2e20a6ac99a7,
  abstract     = {Exacerbations are the key drivers in the costs of chronic obstructive pulmonary disease (COPD). The objective was to examine the costs of COPD exacerbations in relation to differing degrees of severity of exacerbations and of COPD. We identified 202 subjects with COPD, defined according to the BTS and ERS criteria. Exacerbations were divided into mild (self-managed), mild/moderate (telephone contact with a health-care centre and/or the use of anti biotics/systemic corticosteroids), moderate (health-care centre visits) and severe (emergency care visit or hospital admission). Exacerbations were identified by sending the subjects a letter inquiring whether they had any additional respiratory problems or influenza the previous winter. At least one exacerbation was reported by 61 subjects, who were then interviewed about resource use for these events. The average health-care costs per exacerbation were SEK 120(95% CI = 39-246), SEK 354 (252-475), SEK 2111 (1673-2612) and SEK 21852 (14436-29825) for mild, mild/moderate, moderate and severe exacerbations, respectively. Subjects with impaired lung function experienced more severe exacerbations, which was also reflected in the cost of exacerbations per severity of the disease during the 41 month study period (ranging from SEK 224 for mild to SEK 13708 for severe cases, median SEK 940). Exacerbations account for 35-45% of the total per capita health-care costs for COPD. In conclusion, costs varied considerably with the severity of the exacerbation as well as with the severity of COPD. The prevention of moderate-to-severe exacerbations could be very cost-effective and improve the quality of life.},
  author       = {Andersson, F and Borg, S and Jansson, SA and Jonsson, AC and Ericsson, A and Prütz, Christin and Ronmark, E and Lundback, B},
  issn         = {1532-3064},
  keyword      = {OLIN studies,frequency,severity,costs,COPD,exacerbations},
  language     = {eng},
  number       = {9},
  pages        = {700--708},
  publisher    = {Elsevier},
  series       = {Respiratory Medicine},
  title        = {The costs of exacerbations in chronic obstructive pulmonary disease (COPD)},
  url          = {http://dx.doi.org/10.1053/rmed.2002.1334},
  volume       = {96},
  year         = {2002},
}