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A Statistical DOI Estimation Algorithm for a SiPM-Based Clinical SPECT Insert

DrAdda, Ilenia ; Morahan, Ashley J. ; Carminati, Marco ; Erlandsson, Kjell ; Ljungberg, Michael LU orcid ; Hutton, Brian F. and Fiorini, Carlo (2022) In IEEE Transactions on Radiation and Plasma Medical Sciences 6(7). p.771-777
Abstract

A prototype clinical brain SPECT insert has been designed for use in simultaneous SPECT/MRI. The system utilises novel slit-slat collimators which, like pinhole collimators, suffers from parallax errors due to the large incident angle of photons. A statistical algorithm has been developed to determine the depth-of-interaction (DOI) with a view to improving image performance. The importance of DOI correction was demonstrated using Monte Carlo simulation. This simulation also indicated that 4 DOI layers (3×1.5 mm+3.5 mm) may be sufficient. The improvement in event localisation was demonstrated on a single detector before implementing the algorithm on the full clinical prototype where some limitations in event localisation in... (More)

A prototype clinical brain SPECT insert has been designed for use in simultaneous SPECT/MRI. The system utilises novel slit-slat collimators which, like pinhole collimators, suffers from parallax errors due to the large incident angle of photons. A statistical algorithm has been developed to determine the depth-of-interaction (DOI) with a view to improving image performance. The importance of DOI correction was demonstrated using Monte Carlo simulation. This simulation also indicated that 4 DOI layers (3×1.5 mm+3.5 mm) may be sufficient. The improvement in event localisation was demonstrated on a single detector before implementing the algorithm on the full clinical prototype where some limitations in event localisation in layers close to the readout plane were observed. Nevertheless DOI enabled the rejection of poorly localised events with improved resolution in reconstructed line sources.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Biomedical imaging, Calibration, Collimators, depth-of-interaction, Detectors, event localisation., Image reconstruction, Plasmas, Single photon emission computed tomography, SPECT
in
IEEE Transactions on Radiation and Plasma Medical Sciences
volume
6
issue
7
pages
771 - 777
publisher
IEEE - Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • scopus:85122572817
ISSN
2469-7311
DOI
10.1109/TRPMS.2022.3140411
language
English
LU publication?
yes
id
32b07629-bb82-4dae-8af1-f41df2ac9962
date added to LUP
2022-02-18 14:22:49
date last changed
2024-11-19 23:28:11
@article{32b07629-bb82-4dae-8af1-f41df2ac9962,
  abstract     = {{<p>A prototype clinical brain SPECT insert has been designed for use in simultaneous SPECT/MRI. The system utilises novel slit-slat collimators which, like pinhole collimators, suffers from parallax errors due to the large incident angle of photons. A statistical algorithm has been developed to determine the depth-of-interaction (DOI) with a view to improving image performance. The importance of DOI correction was demonstrated using Monte Carlo simulation. This simulation also indicated that 4 DOI layers (3&amp;#x00D7;1.5 mm+3.5 mm) may be sufficient. The improvement in event localisation was demonstrated on a single detector before implementing the algorithm on the full clinical prototype where some limitations in event localisation in layers close to the readout plane were observed. Nevertheless DOI enabled the rejection of poorly localised events with improved resolution in reconstructed line sources.</p>}},
  author       = {{DrAdda, Ilenia and Morahan, Ashley J. and Carminati, Marco and Erlandsson, Kjell and Ljungberg, Michael and Hutton, Brian F. and Fiorini, Carlo}},
  issn         = {{2469-7311}},
  keywords     = {{Biomedical imaging; Calibration; Collimators; depth-of-interaction; Detectors; event localisation.; Image reconstruction; Plasmas; Single photon emission computed tomography; SPECT}},
  language     = {{eng}},
  number       = {{7}},
  pages        = {{771--777}},
  publisher    = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}},
  series       = {{IEEE Transactions on Radiation and Plasma Medical Sciences}},
  title        = {{A Statistical DOI Estimation Algorithm for a SiPM-Based Clinical SPECT Insert}},
  url          = {{http://dx.doi.org/10.1109/TRPMS.2022.3140411}},
  doi          = {{10.1109/TRPMS.2022.3140411}},
  volume       = {{6}},
  year         = {{2022}},
}