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Pulmonell hypertension vanligt vid kronisk lungsjukdom : Europeiska riktlinjer kring utredning och behandling

Kylhammar, David and Rådegran, Göran LU (2017) In Lakartidningen 114.
Abstract

Pulmonary hypertension due to lung diseases In 2015 the European Society of Cardiology and European Respiratory Society published new guidelines on the diagnosis and treatment of pulmonary hypertension (PH). PH due to lung diseases and/or hypoxia was classified as a separate entity. PH is common in lung diseases, but seldom severe. Nevertheless, the presence of PH in a patient with lung disease is associated with worse outcome. If there is clinical suspicion of PH in a patient with lung disease, echocardiography is recommended, and if there are signs of severe PH and/or severe right ventricular dysfunction the patient should be referred to a PH expert centre. Patients may have lung disease and e.g. pulmonary arterial hypertension or... (More)

Pulmonary hypertension due to lung diseases In 2015 the European Society of Cardiology and European Respiratory Society published new guidelines on the diagnosis and treatment of pulmonary hypertension (PH). PH due to lung diseases and/or hypoxia was classified as a separate entity. PH is common in lung diseases, but seldom severe. Nevertheless, the presence of PH in a patient with lung disease is associated with worse outcome. If there is clinical suspicion of PH in a patient with lung disease, echocardiography is recommended, and if there are signs of severe PH and/or severe right ventricular dysfunction the patient should be referred to a PH expert centre. Patients may have lung disease and e.g. pulmonary arterial hypertension or chronic thromboembolic PH simultaneously, and targeted treatments are available in such cases. PH-targeted drugs should, however, not be used to treat PH due to lung diseases, since there are no robust data speaking for their benefit and a risk of impaired arterial oxygenation due to inhibition of hypoxic pulmonary vasoconstriction. Instead, the underlying lung disease should be optimally treated, including long-term oxygen therapy in case of chronic hypoxemia.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Lakartidningen
volume
114
publisher
Swedish Medical Association
external identifiers
  • scopus:85033399216
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
3312512f-9641-4883-a056-9d0a5417b97d
date added to LUP
2017-11-27 16:36:39
date last changed
2018-01-07 12:26:51
@article{3312512f-9641-4883-a056-9d0a5417b97d,
  abstract     = {<p>Pulmonary hypertension due to lung diseases In 2015 the European Society of Cardiology and European Respiratory Society published new guidelines on the diagnosis and treatment of pulmonary hypertension (PH). PH due to lung diseases and/or hypoxia was classified as a separate entity. PH is common in lung diseases, but seldom severe. Nevertheless, the presence of PH in a patient with lung disease is associated with worse outcome. If there is clinical suspicion of PH in a patient with lung disease, echocardiography is recommended, and if there are signs of severe PH and/or severe right ventricular dysfunction the patient should be referred to a PH expert centre. Patients may have lung disease and e.g. pulmonary arterial hypertension or chronic thromboembolic PH simultaneously, and targeted treatments are available in such cases. PH-targeted drugs should, however, not be used to treat PH due to lung diseases, since there are no robust data speaking for their benefit and a risk of impaired arterial oxygenation due to inhibition of hypoxic pulmonary vasoconstriction. Instead, the underlying lung disease should be optimally treated, including long-term oxygen therapy in case of chronic hypoxemia.</p>},
  author       = {Kylhammar, David and Rådegran, Göran},
  issn         = {0023-7205},
  language     = {swe},
  month        = {07},
  publisher    = {Swedish Medical Association},
  series       = {Lakartidningen},
  title        = {Pulmonell hypertension vanligt vid kronisk lungsjukdom : Europeiska riktlinjer kring utredning och behandling},
  volume       = {114},
  year         = {2017},
}