Advanced

Characterization of Hox genes in the bichir, Polypterus palmas

Ledje, Christina LU ; Kim, Chang-aeB and Ruddle, Francis H (2002) In Journal of Experimental Zoology 294(2). p.107-111
Abstract
It has been suggested that the increase in the number of Hox genes may have been one of the key events in vertebrate evolution. Invertebrates have one Hox cluster, while mammals have four. Interestingly, the number of Hox gene clusters is greater in the teleost fishes, zebrafish and medaka, than in mouse and human. The greater number of Hox clusters in the teleosts suggests that Hox gene duplication events have occurred during the radiation of ray-finned fishes. The question is when the Hox gene duplication event(s) that lead to seven Hox clusters in the teleosts actually occurred. We have addressed this question by studying the Hox genes in the bichir, Polypterus palmas. A preliminary PCR-estimation of the number of Hox genes suggests... (More)
It has been suggested that the increase in the number of Hox genes may have been one of the key events in vertebrate evolution. Invertebrates have one Hox cluster, while mammals have four. Interestingly, the number of Hox gene clusters is greater in the teleost fishes, zebrafish and medaka, than in mouse and human. The greater number of Hox clusters in the teleosts suggests that Hox gene duplication events have occurred during the radiation of ray-finned fishes. The question is when the Hox gene duplication event(s) that lead to seven Hox clusters in the teleosts actually occurred. We have addressed this question by studying the Hox genes in the bichir, Polypterus palmas. A preliminary PCR-estimation of the number of Hox genes suggests that Polypterus has five different Hox9 cognate group genes, which may be an indication of more than four Hox clusters in the bichir. (Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Experimental Zoology
volume
294
issue
2
pages
107 - 111
publisher
John Wiley and Sons Inc.
external identifiers
  • wos:000177187600003
  • pmid:12210111
  • scopus:0037103614
ISSN
0022-104X
DOI
10.1002/jez.10152
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Genetics (Closed 2011) (011005100)
id
247a416a-6792-42ad-8f8d-57c4c47f4086 (old id 332290)
date added to LUP
2016-04-01 15:20:32
date last changed
2020-01-22 05:24:40
@article{247a416a-6792-42ad-8f8d-57c4c47f4086,
  abstract     = {It has been suggested that the increase in the number of Hox genes may have been one of the key events in vertebrate evolution. Invertebrates have one Hox cluster, while mammals have four. Interestingly, the number of Hox gene clusters is greater in the teleost fishes, zebrafish and medaka, than in mouse and human. The greater number of Hox clusters in the teleosts suggests that Hox gene duplication events have occurred during the radiation of ray-finned fishes. The question is when the Hox gene duplication event(s) that lead to seven Hox clusters in the teleosts actually occurred. We have addressed this question by studying the Hox genes in the bichir, Polypterus palmas. A preliminary PCR-estimation of the number of Hox genes suggests that Polypterus has five different Hox9 cognate group genes, which may be an indication of more than four Hox clusters in the bichir.},
  author       = {Ledje, Christina and Kim, Chang-aeB and Ruddle, Francis H},
  issn         = {0022-104X},
  language     = {eng},
  number       = {2},
  pages        = {107--111},
  publisher    = {John Wiley and Sons Inc.},
  series       = {Journal of Experimental Zoology},
  title        = {Characterization of Hox genes in the bichir, Polypterus palmas},
  url          = {http://dx.doi.org/10.1002/jez.10152},
  doi          = {10.1002/jez.10152},
  volume       = {294},
  year         = {2002},
}