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Incidence of limb fracture across Europe: Results from the European Prospective Osteoporosis Study (EPOS)

Ismail, AA; Pye, SR; Cockerill, WC; Lunt, M; Silman, AJ; Reeve, J; Banzer, D; Benevolenskaya, LI; Bhalla, A and Armas, JB, et al. (2002) In Osteoporosis International 13(7). p.565-571
Abstract
The aim of this population-based prospective study was to determine the incidence of limb fracture by site and gender in different regions of Europe. Men and women aged 50-79 years were recruited from population registers in 31 European centers. Subjects were invited to attend for an interviewer-administered questionnaire and lateral spinal radiographs. Subjects were subsequently followed up using an annual postal questionnaire which included questions concerning the occurrence of new fractures. Self-reported fractures were confirmed where possible by radiograph, attending physician or subject interview. There were 6451 men and 6936 women followed for a median of 3.0 years. During this time there were 140 incident limb fractures in men and... (More)
The aim of this population-based prospective study was to determine the incidence of limb fracture by site and gender in different regions of Europe. Men and women aged 50-79 years were recruited from population registers in 31 European centers. Subjects were invited to attend for an interviewer-administered questionnaire and lateral spinal radiographs. Subjects were subsequently followed up using an annual postal questionnaire which included questions concerning the occurrence of new fractures. Self-reported fractures were confirmed where possible by radiograph, attending physician or subject interview. There were 6451 men and 6936 women followed for a median of 3.0 years. During this time there were 140 incident limb fractures in men and 391 in women. The age-adjusted incidence of any limb fracture was 7,3/1000 person-years [pyrs] in men and 19 per 1000 pyrs in women, equivalent to a 2,5 times excess in women. Among women, the incidence of hip, humerus and distal forearm fracture, though not 'other' limb fracture, increased with age, while in men only the incidence of hip and humerus fracture increased with age. Among women, there was evidence of significant variation in the occurrence of hip, distal forearm and humerus fractures across Europe, with incidence rates higher in Scandinavia than in other European regions. though for distal forearm fracture the incidence in east Europe was similar to that observed in Scandinavia. Among men, there was no evidence of significant geographic variation in the occurrence of these fractures. This is the first large population-based study to characterize the incidence of limb fracture in men and women over 50 years of age across Europe. There are substantial differences in the descriptive epidemiology of limb fracture by region and gender. (Less)
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publication status
published
subject
keywords
limb fracture, incidence, epidemiology, Europe, osteoporosis
in
Osteoporosis International
volume
13
issue
7
pages
565 - 571
publisher
Springer
external identifiers
  • wos:000176999400007
  • pmid:12111017
  • scopus:0036068426
ISSN
1433-2965
DOI
10.1007/s001980200074
language
English
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yes
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4ca25d08-3e12-4304-9d33-ec53f04806c3 (old id 332558)
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2007-10-23 10:48:43
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2017-12-03 03:40:21
@article{4ca25d08-3e12-4304-9d33-ec53f04806c3,
  abstract     = {The aim of this population-based prospective study was to determine the incidence of limb fracture by site and gender in different regions of Europe. Men and women aged 50-79 years were recruited from population registers in 31 European centers. Subjects were invited to attend for an interviewer-administered questionnaire and lateral spinal radiographs. Subjects were subsequently followed up using an annual postal questionnaire which included questions concerning the occurrence of new fractures. Self-reported fractures were confirmed where possible by radiograph, attending physician or subject interview. There were 6451 men and 6936 women followed for a median of 3.0 years. During this time there were 140 incident limb fractures in men and 391 in women. The age-adjusted incidence of any limb fracture was 7,3/1000 person-years [pyrs] in men and 19 per 1000 pyrs in women, equivalent to a 2,5 times excess in women. Among women, the incidence of hip, humerus and distal forearm fracture, though not 'other' limb fracture, increased with age, while in men only the incidence of hip and humerus fracture increased with age. Among women, there was evidence of significant variation in the occurrence of hip, distal forearm and humerus fractures across Europe, with incidence rates higher in Scandinavia than in other European regions. though for distal forearm fracture the incidence in east Europe was similar to that observed in Scandinavia. Among men, there was no evidence of significant geographic variation in the occurrence of these fractures. This is the first large population-based study to characterize the incidence of limb fracture in men and women over 50 years of age across Europe. There are substantial differences in the descriptive epidemiology of limb fracture by region and gender.},
  author       = {Ismail, AA and Pye, SR and Cockerill, WC and Lunt, M and Silman, AJ and Reeve, J and Banzer, D and Benevolenskaya, LI and Bhalla, A and Armas, JB and Cannata, JB and Cooper, C and Delmas, PD and Dequeker, J and Dilsen, G and Falch, JA and Felsch, B and Felsenberg, D and Finn, JD and Gennari, C and Hoszowski, K and Jajic, I and Janott, J and Johnell, Olof and Kanis, JA and Kragl, G and Vaz, AL and Lorenc, R and Lyritis, G and Marchand, F and Masaryk, P and Matthis, C and Miazgowski, T and Naves-Diaz, M and Pols, HAP and Poor, G and Rapado, A and Raspe, HH and Reid, DM and Reisinger, W and Scheidt-Nave, C and Stepan, J and Todd, C and Weber, K and Woolf, AD and O'Neill, TW},
  issn         = {1433-2965},
  keyword      = {limb fracture,incidence,epidemiology,Europe,osteoporosis},
  language     = {eng},
  number       = {7},
  pages        = {565--571},
  publisher    = {Springer},
  series       = {Osteoporosis International},
  title        = {Incidence of limb fracture across Europe: Results from the European Prospective Osteoporosis Study (EPOS)},
  url          = {http://dx.doi.org/10.1007/s001980200074},
  volume       = {13},
  year         = {2002},
}