Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells.
(2012) In Pancreatology 12(6). p.467-474- Abstract
- Polysaccharide-K (PSK, Krestin(®)) is a natural remedy and one of the most commonly used medicinal mushroom extracts. It has been used as oral adjuvant treatment in cancer therapy in Japan and other Asian countries for more than 40 years. PSK is thought to be an immune modulator, however, its antitumor actions remain undefined. The aim of the present study was to investigate underlying mechanisms by which PSK exerts its antitumor effects on malignant epithelial cells.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3347524
- author
- Rosendahl, Ann LU ; Sun, Chen LU ; Wu, Dequan and Andersson, Roland LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Pancreatology
- volume
- 12
- issue
- 6
- pages
- 467 - 474
- publisher
- Karger
- external identifiers
-
- wos:000313026700001
- pmid:23217280
- scopus:84873085234
- pmid:23217280
- ISSN
- 1424-3903
- DOI
- 10.1016/j.pan.2012.09.004
- language
- English
- LU publication?
- yes
- id
- 44267a54-c39d-4895-8646-18368bc966af (old id 3347524)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23217280?dopt=Abstract
- date added to LUP
- 2016-04-04 08:47:39
- date last changed
- 2022-02-28 05:27:53
@article{44267a54-c39d-4895-8646-18368bc966af, abstract = {{Polysaccharide-K (PSK, Krestin(®)) is a natural remedy and one of the most commonly used medicinal mushroom extracts. It has been used as oral adjuvant treatment in cancer therapy in Japan and other Asian countries for more than 40 years. PSK is thought to be an immune modulator, however, its antitumor actions remain undefined. The aim of the present study was to investigate underlying mechanisms by which PSK exerts its antitumor effects on malignant epithelial cells.}}, author = {{Rosendahl, Ann and Sun, Chen and Wu, Dequan and Andersson, Roland}}, issn = {{1424-3903}}, language = {{eng}}, number = {{6}}, pages = {{467--474}}, publisher = {{Karger}}, series = {{Pancreatology}}, title = {{Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells.}}, url = {{http://dx.doi.org/10.1016/j.pan.2012.09.004}}, doi = {{10.1016/j.pan.2012.09.004}}, volume = {{12}}, year = {{2012}}, }