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Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells.

Rosendahl, Ann LU ; Sun, Chen LU ; Wu, Dequan and Andersson, Roland LU (2012) In Pancreatology 12(6). p.467-474
Abstract
Polysaccharide-K (PSK, Krestin(®)) is a natural remedy and one of the most commonly used medicinal mushroom extracts. It has been used as oral adjuvant treatment in cancer therapy in Japan and other Asian countries for more than 40 years. PSK is thought to be an immune modulator, however, its antitumor actions remain undefined. The aim of the present study was to investigate underlying mechanisms by which PSK exerts its antitumor effects on malignant epithelial cells.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pancreatology
volume
12
issue
6
pages
467 - 474
publisher
Karger
external identifiers
  • wos:000313026700001
  • pmid:23217280
  • scopus:84873085234
ISSN
1424-3903
DOI
10.1016/j.pan.2012.09.004
language
English
LU publication?
yes
id
44267a54-c39d-4895-8646-18368bc966af (old id 3347524)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23217280?dopt=Abstract
date added to LUP
2013-01-02 14:37:14
date last changed
2017-02-12 04:19:09
@article{44267a54-c39d-4895-8646-18368bc966af,
  abstract     = {Polysaccharide-K (PSK, Krestin(®)) is a natural remedy and one of the most commonly used medicinal mushroom extracts. It has been used as oral adjuvant treatment in cancer therapy in Japan and other Asian countries for more than 40 years. PSK is thought to be an immune modulator, however, its antitumor actions remain undefined. The aim of the present study was to investigate underlying mechanisms by which PSK exerts its antitumor effects on malignant epithelial cells.},
  author       = {Rosendahl, Ann and Sun, Chen and Wu, Dequan and Andersson, Roland},
  issn         = {1424-3903},
  language     = {eng},
  number       = {6},
  pages        = {467--474},
  publisher    = {Karger},
  series       = {Pancreatology},
  title        = {Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells.},
  url          = {http://dx.doi.org/10.1016/j.pan.2012.09.004},
  volume       = {12},
  year         = {2012},
}