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Metal-on-metal joint bearings and hematopoetic malignancy A review

Wagner, Philippe LU ; Olsson, Håkan LU ; Ranstam, Jonas LU ; Robertsson, Otto LU ; Zheng, Ming Hao and Lidgren, Lars LU (2012) In Acta Orthopaedica 83(6). p.553-558
Abstract
This is a review of the hip arthroplasty era. We concentrate on new metal bearings, surface replacements, and the lessons not learned, and we highlight recent reports on malignancies and joint implants. A low incidence of blood malignancies has been found in bone marrow taken at prosthetic surgery. The incidence is increased after replacement with knee implants that release very low systemic levels of metal ions. A carcinogenic effect of the high levels of metal ions released by large metal-on-metal implants cannot be excluded. Ongoing Swedish implant registry studies going back to 1975 can serve as a basis for evaluation of this risk.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica
volume
83
issue
6
pages
553 - 558
publisher
Taylor & Francis
external identifiers
  • wos:000311679900002
  • scopus:84870277385
ISSN
1745-3682
DOI
10.3109/17453674.2012.747055
language
English
LU publication?
yes
id
6c69944e-af35-473b-8f22-60e384001458 (old id 3372602)
date added to LUP
2013-02-01 06:59:56
date last changed
2017-04-30 11:33:01
@article{6c69944e-af35-473b-8f22-60e384001458,
  abstract     = {This is a review of the hip arthroplasty era. We concentrate on new metal bearings, surface replacements, and the lessons not learned, and we highlight recent reports on malignancies and joint implants. A low incidence of blood malignancies has been found in bone marrow taken at prosthetic surgery. The incidence is increased after replacement with knee implants that release very low systemic levels of metal ions. A carcinogenic effect of the high levels of metal ions released by large metal-on-metal implants cannot be excluded. Ongoing Swedish implant registry studies going back to 1975 can serve as a basis for evaluation of this risk.},
  author       = {Wagner, Philippe and Olsson, Håkan and Ranstam, Jonas and Robertsson, Otto and Zheng, Ming Hao and Lidgren, Lars},
  issn         = {1745-3682},
  language     = {eng},
  number       = {6},
  pages        = {553--558},
  publisher    = {Taylor & Francis},
  series       = {Acta Orthopaedica},
  title        = {Metal-on-metal joint bearings and hematopoetic malignancy A review},
  url          = {http://dx.doi.org/10.3109/17453674.2012.747055},
  volume       = {83},
  year         = {2012},
}