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Neosordarin and hydroxysordarin, two new antifungal agents from Sordaria araneosa

Davoli, P; Engel, G; Werle, A; Sterner, Olov LU and Anke, T (2002) In Journal of Antibiotics 55(4). p.377-382
Abstract
Two novel antifungal agents belonging to the sordarin family have been isolated from fermentations of Sordaria araneosa by bioassay-guided purification and their structures elucidated by NMR techniques. Neosordarin (1) is closely related to the recently discovered hypoxysordarin (2), with only small differences on the aliphatic side chain acylating the hydroxyl in the 3'-position of the sordarose moiety. Hydroxysordarin (3) closely resembles sordarin (4), the only slight difference being the replacement of sordarose with altrose as the sugar unit.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Antibiotics
volume
55
issue
4
pages
377 - 382
publisher
Japan Antibiotics Research Association
external identifiers
  • pmid:12061545
  • wos:000175224300004
  • scopus:0036253108
ISSN
0021-8820
language
English
LU publication?
yes
id
bbfba442-5edf-40e5-b75c-dd9985f2fcca (old id 339571)
date added to LUP
2007-08-15 16:29:20
date last changed
2017-01-01 06:42:59
@article{bbfba442-5edf-40e5-b75c-dd9985f2fcca,
  abstract     = {Two novel antifungal agents belonging to the sordarin family have been isolated from fermentations of Sordaria araneosa by bioassay-guided purification and their structures elucidated by NMR techniques. Neosordarin (1) is closely related to the recently discovered hypoxysordarin (2), with only small differences on the aliphatic side chain acylating the hydroxyl in the 3'-position of the sordarose moiety. Hydroxysordarin (3) closely resembles sordarin (4), the only slight difference being the replacement of sordarose with altrose as the sugar unit.},
  author       = {Davoli, P and Engel, G and Werle, A and Sterner, Olov and Anke, T},
  issn         = {0021-8820},
  language     = {eng},
  number       = {4},
  pages        = {377--382},
  publisher    = {Japan Antibiotics Research Association},
  series       = {Journal of Antibiotics},
  title        = {Neosordarin and hydroxysordarin, two new antifungal agents from Sordaria araneosa},
  volume       = {55},
  year         = {2002},
}