Inertia induced breakdown of acoustic sorting efficiency at high flow rates
(2021) 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 p.895-896- Abstract
We investigated the impact of inertial forces on acoustic sorting at high sample throughputs. Above a critical flow rate, we observed an unexpected inertia induced breakdown of the sorting efficiency that is not due to the wall induced lift force and was not previously described in the literature. We analyzed the effect experimentally and theoretically, providing an explanation to the phenomena, and suggest conditions to maximize the sample throughput, while keeping the sorting efficiency intact. The observed phenomena is generic to all separation techniques that rely on field based (electrical, magnetic, acoustic) forces acting on cells/particles.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/339a1dbc-7b2b-48eb-8bb8-1d3ec1ef2435
- author
- Undvall, Eva LU ; Garofalo, Fabio LU ; Procopio, Giuseppe ; Lenshof, Andreas LU ; Laurell, Thomas LU and Baasch, Thierry LU
- organization
- publishing date
- 2021
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Acoustic particle manipulation, Fluid mechanics, High throughput, Inertia, Microfluidic sorting
- host publication
- MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- pages
- 2 pages
- publisher
- Chemical and Biological Microsystems Society
- conference name
- 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
- conference location
- Palm Springs, Virtual, United States
- conference dates
- 2021-10-10 - 2021-10-14
- external identifiers
-
- scopus:85136941020
- ISBN
- 9781733419031
- language
- English
- LU publication?
- yes
- id
- 339a1dbc-7b2b-48eb-8bb8-1d3ec1ef2435
- date added to LUP
- 2022-11-08 11:37:08
- date last changed
- 2023-10-23 06:29:03
@inproceedings{339a1dbc-7b2b-48eb-8bb8-1d3ec1ef2435, abstract = {{<p>We investigated the impact of inertial forces on acoustic sorting at high sample throughputs. Above a critical flow rate, we observed an unexpected inertia induced breakdown of the sorting efficiency that is not due to the wall induced lift force and was not previously described in the literature. We analyzed the effect experimentally and theoretically, providing an explanation to the phenomena, and suggest conditions to maximize the sample throughput, while keeping the sorting efficiency intact. The observed phenomena is generic to all separation techniques that rely on field based (electrical, magnetic, acoustic) forces acting on cells/particles.</p>}}, author = {{Undvall, Eva and Garofalo, Fabio and Procopio, Giuseppe and Lenshof, Andreas and Laurell, Thomas and Baasch, Thierry}}, booktitle = {{MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences}}, isbn = {{9781733419031}}, keywords = {{Acoustic particle manipulation; Fluid mechanics; High throughput; Inertia; Microfluidic sorting}}, language = {{eng}}, pages = {{895--896}}, publisher = {{Chemical and Biological Microsystems Society}}, title = {{Inertia induced breakdown of acoustic sorting efficiency at high flow rates}}, year = {{2021}}, }