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Oligomeric acylphloroglucinols from myrtle (Myrtus communis)

Appendino, G; Bianchi, F; Minassi, A; Sterner, Olov LU ; Ballero, M and Gibbons, S (2002) In Journal of Natural Products 65(3). p.334-338
Abstract
The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Natural Products
volume
65
issue
3
pages
334 - 338
publisher
The American Chemical Society
external identifiers
  • pmid:11908974
  • wos:000174627400016
  • scopus:0036201069
ISSN
0163-3864
DOI
10.1021/np010441b
language
English
LU publication?
yes
id
edc6007c-78cc-47b8-a855-5154b06283d0 (old id 341064)
date added to LUP
2007-08-07 15:34:19
date last changed
2017-11-05 04:38:57
@article{edc6007c-78cc-47b8-a855-5154b06283d0,
  abstract     = {The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.},
  author       = {Appendino, G and Bianchi, F and Minassi, A and Sterner, Olov and Ballero, M and Gibbons, S},
  issn         = {0163-3864},
  language     = {eng},
  number       = {3},
  pages        = {334--338},
  publisher    = {The American Chemical Society},
  series       = {Journal of Natural Products},
  title        = {Oligomeric acylphloroglucinols from myrtle (Myrtus communis)},
  url          = {http://dx.doi.org/10.1021/np010441b},
  volume       = {65},
  year         = {2002},
}