Telomere terminating with centromere-specific repeats is closely associated with a transposon derived gene in Chironomus pallidivittatus
(2002) In Chromosoma 110(8). p.532-541- Abstract
- We provide evidence that centromere-specific 155 bp DNA repeats terminate one pair of telomeres at the telocentric, left end of the short fourth chromosome in Chironomus pallidivittatus. Earlier evidence indicated that all other telomeres are terminated by 340 bp telomere-specific repeats. DNA that borders the 155 bp repeat contains a transcriptionally active 396 codon open reading frame (ORF) a few kilobases away from the repeat array. The conceptual product of the ORF has regions with similarities to transposase, DNA binding and endonuclease motifs and is likely to have an evolutionary origin in a transposon. It is flanked, within degenerate inverted repeats, by a modified form of an element. Cp80, that has previously been found to... (More)
- We provide evidence that centromere-specific 155 bp DNA repeats terminate one pair of telomeres at the telocentric, left end of the short fourth chromosome in Chironomus pallidivittatus. Earlier evidence indicated that all other telomeres are terminated by 340 bp telomere-specific repeats. DNA that borders the 155 bp repeat contains a transcriptionally active 396 codon open reading frame (ORF) a few kilobases away from the repeat array. The conceptual product of the ORF has regions with similarities to transposase, DNA binding and endonuclease motifs and is likely to have an evolutionary origin in a transposon. It is flanked, within degenerate inverted repeats, by a modified form of an element. Cp80, that has previously been found to insert only into 155 bp repeats and that contains a putative CENP-B box and a region that is prone to recombine. The ORF may therefore have a functional relation to the centromeric region. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/341221
- author
- Rosén, Monika LU ; Castillejo-Lopez, Casimiro LU and Edström, Jan-Erik LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Chromosoma
- volume
- 110
- issue
- 8
- pages
- 532 - 541
- publisher
- Springer
- external identifiers
-
- pmid:12068970
- wos:000174681400003
- scopus:0036185473
- ISSN
- 0009-5915
- DOI
- 10.1007/s00412-001-0176-y
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Genetics (Closed 2011) (011005100), Invertebral Developmental Biology, Udo Haecker's group (013212048)
- id
- 0bab175a-a51a-401a-8a89-e92def93c370 (old id 341221)
- date added to LUP
- 2016-04-01 16:17:29
- date last changed
- 2022-02-27 20:14:17
@article{0bab175a-a51a-401a-8a89-e92def93c370, abstract = {{We provide evidence that centromere-specific 155 bp DNA repeats terminate one pair of telomeres at the telocentric, left end of the short fourth chromosome in Chironomus pallidivittatus. Earlier evidence indicated that all other telomeres are terminated by 340 bp telomere-specific repeats. DNA that borders the 155 bp repeat contains a transcriptionally active 396 codon open reading frame (ORF) a few kilobases away from the repeat array. The conceptual product of the ORF has regions with similarities to transposase, DNA binding and endonuclease motifs and is likely to have an evolutionary origin in a transposon. It is flanked, within degenerate inverted repeats, by a modified form of an element. Cp80, that has previously been found to insert only into 155 bp repeats and that contains a putative CENP-B box and a region that is prone to recombine. The ORF may therefore have a functional relation to the centromeric region.}}, author = {{Rosén, Monika and Castillejo-Lopez, Casimiro and Edström, Jan-Erik}}, issn = {{0009-5915}}, language = {{eng}}, number = {{8}}, pages = {{532--541}}, publisher = {{Springer}}, series = {{Chromosoma}}, title = {{Telomere terminating with centromere-specific repeats is closely associated with a transposon derived gene in Chironomus pallidivittatus}}, url = {{http://dx.doi.org/10.1007/s00412-001-0176-y}}, doi = {{10.1007/s00412-001-0176-y}}, volume = {{110}}, year = {{2002}}, }