Embedding DNA in surfactant mesophases: The phase diagram of the ternary system dodecyltrimethylammonium-DNA/monoolein/water in comparison to the DNA-free analogue.
(2013) In Journal of Colloid and Interface Science 394(Online 28 December 2012). p.360-367- Abstract
- The self-assembly of a true ternary mixture comprising an electroneutral complex of DNA anions and surfactant cations (dodecyltrimethylammonium cations, DTA), water, and nonionic surfactant (monoolein, MO) has been studied. The phase diagrams of two systems, DTA-DNA/MO/water and, for comparison, dodecyltrimethylammonium bromide (DTAB)/MO/water, were obtained by visual inspection, microscopic examination under polarized light, small-angle X-ray scattering (SAXS) and deuterium NMR ((2)H NMR) at 298K and normal pressure. The isothermal phase diagram of the DTA-DNA/MO/water system contains four liquid crystalline (LC) phase regions (reversed hexagonal, Pn3m, Ia3d, lamellar). The supramolecular assemblies evolve from a bicontinuous cubic... (More)
- The self-assembly of a true ternary mixture comprising an electroneutral complex of DNA anions and surfactant cations (dodecyltrimethylammonium cations, DTA), water, and nonionic surfactant (monoolein, MO) has been studied. The phase diagrams of two systems, DTA-DNA/MO/water and, for comparison, dodecyltrimethylammonium bromide (DTAB)/MO/water, were obtained by visual inspection, microscopic examination under polarized light, small-angle X-ray scattering (SAXS) and deuterium NMR ((2)H NMR) at 298K and normal pressure. The isothermal phase diagram of the DTA-DNA/MO/water system contains four liquid crystalline (LC) phase regions (reversed hexagonal, Pn3m, Ia3d, lamellar). The supramolecular assemblies evolve from a bicontinuous cubic structure of the reversed type to the two-dimensional hexagonal phase as the content of DTA-DNA is increased. While DTA-DNA tends to form a reversed hexagonal phase, DTAB is incorporated into the existing lamellar phase formed by MO and water giving rise to swelling and to significant extension of the lamellar phase region. There is only a small tendency of the cubic phases existing in the binary system MO/water to accommodate DTAB or DTA-DNA. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3438354
- author
- Bilalov, Azat LU ; Elsing, Jonas LU ; Haas, Eva ; Schmidt, Claudia and Olsson, Ulf LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Colloid and Interface Science
- volume
- 394
- issue
- Online 28 December 2012
- pages
- 360 - 367
- publisher
- Elsevier
- external identifiers
-
- wos:000315325400046
- pmid:23347998
- scopus:84873705258
- pmid:23347998
- ISSN
- 1095-7103
- DOI
- 10.1016/j.jcis.2012.11.067
- language
- English
- LU publication?
- yes
- id
- 867f7870-b6db-4d88-97e2-6bbd006a4019 (old id 3438354)
- date added to LUP
- 2016-04-01 10:12:09
- date last changed
- 2022-04-04 03:25:27
@article{867f7870-b6db-4d88-97e2-6bbd006a4019,
abstract = {{The self-assembly of a true ternary mixture comprising an electroneutral complex of DNA anions and surfactant cations (dodecyltrimethylammonium cations, DTA), water, and nonionic surfactant (monoolein, MO) has been studied. The phase diagrams of two systems, DTA-DNA/MO/water and, for comparison, dodecyltrimethylammonium bromide (DTAB)/MO/water, were obtained by visual inspection, microscopic examination under polarized light, small-angle X-ray scattering (SAXS) and deuterium NMR ((2)H NMR) at 298K and normal pressure. The isothermal phase diagram of the DTA-DNA/MO/water system contains four liquid crystalline (LC) phase regions (reversed hexagonal, Pn3m, Ia3d, lamellar). The supramolecular assemblies evolve from a bicontinuous cubic structure of the reversed type to the two-dimensional hexagonal phase as the content of DTA-DNA is increased. While DTA-DNA tends to form a reversed hexagonal phase, DTAB is incorporated into the existing lamellar phase formed by MO and water giving rise to swelling and to significant extension of the lamellar phase region. There is only a small tendency of the cubic phases existing in the binary system MO/water to accommodate DTAB or DTA-DNA.}},
author = {{Bilalov, Azat and Elsing, Jonas and Haas, Eva and Schmidt, Claudia and Olsson, Ulf}},
issn = {{1095-7103}},
language = {{eng}},
number = {{Online 28 December 2012}},
pages = {{360--367}},
publisher = {{Elsevier}},
series = {{Journal of Colloid and Interface Science}},
title = {{Embedding DNA in surfactant mesophases: The phase diagram of the ternary system dodecyltrimethylammonium-DNA/monoolein/water in comparison to the DNA-free analogue.}},
url = {{http://dx.doi.org/10.1016/j.jcis.2012.11.067}},
doi = {{10.1016/j.jcis.2012.11.067}},
volume = {{394}},
year = {{2013}},
}