Early-term Birth (37-38 Weeks) and Mortality in Young Adulthood.
(2013) In Epidemiology- Abstract
- BACKGROUND:: Early-term birth (gestational age, 37-38 weeks) has been associated with increased infant mortality relative to later-term birth, but mortality beyond infancy has not been studied. We examined the association between early-term birth and mortality through young adulthood. METHODS:: We conducted a national cohort study of 679,981 singleton births in Sweden in 1973-1979, followed up for all-cause and cause-specific mortality through 2008 (ages 29-36 years). RESULTS:: There were 10,656 deaths in 21.5 million person-years of follow-up. Among those still alive at the beginning of each age range, early-term birth relative to those born at 39-42 weeks was associated with increased mortality in the neonatal period (0-27 days: adjusted... (More)
- BACKGROUND:: Early-term birth (gestational age, 37-38 weeks) has been associated with increased infant mortality relative to later-term birth, but mortality beyond infancy has not been studied. We examined the association between early-term birth and mortality through young adulthood. METHODS:: We conducted a national cohort study of 679,981 singleton births in Sweden in 1973-1979, followed up for all-cause and cause-specific mortality through 2008 (ages 29-36 years). RESULTS:: There were 10,656 deaths in 21.5 million person-years of follow-up. Among those still alive at the beginning of each age range, early-term birth relative to those born at 39-42 weeks was associated with increased mortality in the neonatal period (0-27 days: adjusted hazard ratio = 2.18 [95% confidence interval = 1.89-2.51]), postneonatal period (28-364 days: 1.66 [1.44-1.92]), early childhood (1-5 years: 1.29 [1.10-1.51]), and young adulthood (18-36 years: 1.14 [1.05-1.24]), but not in late childhood/adolescence (6-17 years: 0.97 [0.84-1.12]). In young adulthood, early-term birth was strongly associated with death from congenital anomalies and endocrine disorders, especially diabetes (2.89 [1.54-5.43]). CONCLUSIONS:: In this large national cohort study, early-term birth was independently associated with increased mortality in infancy, early childhood, and young adulthood. Lowest short-term and long-term mortality was among those born at 39-42 weeks. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3438516
- author
- Crump, Casey LU ; Sundquist, Kristina LU ; Winkleby, Marilyn LU and Sundquist, Jan LU
- organization
- publishing date
- 2013-01-18
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Epidemiology
- publisher
- Wolters Kluwer
- external identifiers
-
- wos:000314728000015
- pmid:23337240
- scopus:84873404778
- pmid:23337240
- ISSN
- 1531-5487
- DOI
- 10.1097/EDE.0b013e318280da0f
- language
- English
- LU publication?
- yes
- id
- 90f4ce07-c314-4640-a2ba-1348437cdc77 (old id 3438516)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23337240?dopt=Abstract
- date added to LUP
- 2016-04-04 07:12:25
- date last changed
- 2022-03-30 22:02:24
@article{90f4ce07-c314-4640-a2ba-1348437cdc77,
abstract = {{BACKGROUND:: Early-term birth (gestational age, 37-38 weeks) has been associated with increased infant mortality relative to later-term birth, but mortality beyond infancy has not been studied. We examined the association between early-term birth and mortality through young adulthood. METHODS:: We conducted a national cohort study of 679,981 singleton births in Sweden in 1973-1979, followed up for all-cause and cause-specific mortality through 2008 (ages 29-36 years). RESULTS:: There were 10,656 deaths in 21.5 million person-years of follow-up. Among those still alive at the beginning of each age range, early-term birth relative to those born at 39-42 weeks was associated with increased mortality in the neonatal period (0-27 days: adjusted hazard ratio = 2.18 [95% confidence interval = 1.89-2.51]), postneonatal period (28-364 days: 1.66 [1.44-1.92]), early childhood (1-5 years: 1.29 [1.10-1.51]), and young adulthood (18-36 years: 1.14 [1.05-1.24]), but not in late childhood/adolescence (6-17 years: 0.97 [0.84-1.12]). In young adulthood, early-term birth was strongly associated with death from congenital anomalies and endocrine disorders, especially diabetes (2.89 [1.54-5.43]). CONCLUSIONS:: In this large national cohort study, early-term birth was independently associated with increased mortality in infancy, early childhood, and young adulthood. Lowest short-term and long-term mortality was among those born at 39-42 weeks.}},
author = {{Crump, Casey and Sundquist, Kristina and Winkleby, Marilyn and Sundquist, Jan}},
issn = {{1531-5487}},
language = {{eng}},
month = {{01}},
publisher = {{Wolters Kluwer}},
series = {{Epidemiology}},
title = {{Early-term Birth (37-38 Weeks) and Mortality in Young Adulthood.}},
url = {{http://dx.doi.org/10.1097/EDE.0b013e318280da0f}},
doi = {{10.1097/EDE.0b013e318280da0f}},
year = {{2013}},
}